ZR-75-1
Human breast carcinoma cell line. Frozen cryovial. 1.5 Mio. cells/ml.
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Human breast carcinoma cell line ZR-75-1
Organism: Homo sapiens (human)
Ethnicity: Caucasian
Age: 63 years old
Gender: Female
Tissue: Breast (mammary gland); metastatic site: ascites
Morphology: Epithelial
Cell type: Ductal carcinoma
Growth Properties: Adherent
Description: This cell line was established in 1978 by Engel et al. from a malignant ascetic effusion. The cells produce high levels of MUC-1 mucin mRNA, low levels of MUC-2 mRNA but do not express the MUC-3 gene.
References:
Kohrmann et al. 2009; Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature