Thermo Scientific™ Q Exactive™ BioPharma Platform
The Thermo Scientific™ Q Exactive™ Plus and Q Exactive™ HF Hybrid Quadrupole-Orbitrap™ mass spectrometers adds superior denatured and native MS intact analysis and subunit top/middle-down analysis capabilities to the most powerful benchtop peptide mapping instruments available. When combined with Thermo Scientific™ BioPharma Finder™ software it provides a complete integrated hardware and software solution for BioPharma chara…
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Great results
Proteomics
Easy to use, user friendly, great results for disulfide linkage analysis.
Review Date: 23 May 2022 | Thermo Fisher Scientific
Great instrument.
Biopharma analytical assays
Very easy to use instrument. The quality of the data is astonishing which makes it very easy to understand and to analyze.
Review Date: 12 Apr 2021 | Thermo Fisher Scientific
Outstanding results.
Metabolite profiling in biological matrices
Remarkable specificity and reproducible results without sacrificing sensitivity. More accurate and reliable results for doping analysis for small and large molecules. It's east to use and handle. Very good customer feedback and troubleshooting on instrument complaints within week days.
Review Date: 17 Mar 2021 | Thermo Fisher Scientific
The best.
Clinical samples, qualitative and quantitative
The best instrument ever made. Period. I believe this is the ultimate frontier in mass spectrometry.
Review Date: 9 Dec 2019 | Thermo Fisher Scientific
The Thermo Scientific™ Q Exactive™ Plus and Q Exactive™ HF Hybrid Quadrupole-Orbitrap™ mass spectrometers adds superior denatured and native MS intact analysis and subunit top/middle-down analysis capabilities to the most powerful benchtop peptide mapping instruments available.
When combined with Thermo Scientific™ BioPharma Finder™ software it provides a complete integrated hardware and software solution for BioPharma characterization.
The Thermo Scientific™ Q Exactive™ BioPharma platform offers distinct operational modes that have been optimized for the top 3 protein characterization workflows:
- High Mass Range (HMR) mode was designed specifically for intact therapeutic protein workflows with the aim of providing ease of use an flexibility as needed. HMR mode is optimized for both conventional intact monoclonal antibody analysis performed in denaturing conditions, as well as native MS analysis which is ideal for antibody drug conjugates (ADCs) and other heterogeneous antibody samples
- Protein mode on the Q Exactive HF is a powerful combination that has set the standard for the highest quality isotopically resolved data achievable on a benchtop mass spectrometer. Deconvolution of subunit MS spectra is easy and powerful with Thermo Scientific™ BioPharma Finder™ Software
- Peptide mapping with Standard mode is state-of-the-art with the Q Exactive BioPharma, which is a culmination of decades of leadership in the development of data dependent acquisition (DDA)
