Bond Elut C2 is a fairly nonpolar sorbent because of the short chain length of the functional group. C2 is often used during the process of method development if analytes are retained too strongly on a C8 or C18 phase. The polarity of C2 is slightly lower than a cyano phase for polar interactions.
Bond Elut C8 is very similar in property to C18, but is not as retentive for nonpolar compounds due to its shorter hydrocarbon chain and therefore reduced carbon loading. C8 is an excellent replacement for C18 when analytes are too strongly retained for effective elution.
Bond Elut Carbon cartridges are packed with ultrapure graphitized carbon particles that have been optimized for the absorption of pigments in food, fruits and vegetables, and small organic residues in wastewater. The powerful retention mechanisms of these products are appropriate for a broad range of analytes. In addition, careful manufacturing techniques result in lower carbon fines on the wall of the device.
CBA is a midpolarity sorbent and weak cation exchanger (pKa 4.8). It can be used with a wider range of counterions than lower pKa sorbents like SCX, and will demonstrate easier elution of quaternary amine functionalized analytes.
Bond Elut Cellulose columns utilize a pure microgranular cellulose powder that is packed between two, 20 µm polyethylene frits. The cellulose phase is very stable over a wide pH range and contains an extremely low metal content (Fe and CU content less than 5 ppm).
The Bond Elut Certify extraction cartridge utilizes a packed bed consisting of a special, nonpolar C8 sorbent and a strong cation exchanger (SCX). Certify is most commonly used to extract basic (cationic) drugs from urine and blood, but it is also very effective for extracting a wide range of compounds from a diverse number of aqueous matrices.
Bond Elut Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with nonpolar C8 and strong anion-exchange (SAX) sorbent. It has been optimized for acidic drugs, such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen, and other compounds tha…
Bond Elut CH is a midpolarity sorbent that exhibits unique selectivities for certain analytes. When employed as a nonpolar sorbent, CH has the approximate polarity of a C2 sorbent. Bond Elut CH is often a good choice when nonpolar sorbents, such as C18, C8, or C2, do not provide the desired selectivity.
A medium polarity sorbent with many uses, Bond Elut Cyano (CN) is ideal for applications in which extremely nonpolar compounds would be irreversibly retained on high carbon load sorbents, such as C8 and C18. This endcapped version of the cyano sorbent is best utilized when extracting analytes from an aqueous matrix.
Bond Elut DEA bears some resemblance to Bond Elut NH2 in its properties, but with a slightly lower capacity as an anion-exchange sorbent. DEA has a moderately nonpolar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C8, but less polar than C2 or CN-E.
