Products & Reviews

This HTRF kit detects changes of cAMP accumulation in response to Gs coupled GPCR activation or inhibition.

Universal Assay for Serine/Threonine KinasesCisbio's line of HTRF® KinEASE™ STK kits are based on our patented HTRF® technology and can be used as a universal tool for assessing Serine/Threonine kinase activity. These assays use a proprietary antibody and a choice of three biotinylated substrates developed by Upstate to rapidly produce high quality kinase results. Our HTRF KinEASE™ STK kits have been validated on more than 107…

Cisbio offers a line of three ready-to-use assays for measuring cAMP using HTRF® technology. Each kit is optimized for detecting a specific range of cAMP concentrations to allow fine tuning of assay sensitivity. These kits enable high quality, cell-based assay screening in 96-, 384- or 1536-well formats.

An easy way to assess tag accessibilityThe production of fusion proteins often raises the issues not only of their structural integrity after isolation, but also of the accessibility of the associated tag. In the case of GST or 6HIS tagged proteins, this verification can be achieved with HTRF® GST and 6HIS check kits. These two assays are competitive immunoassays in which the anti-GST or anti-6HIS Cryptate conjugates bind dire…

A new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic advantages of an HTRF® system: totally homogeneous, detection via fluorescence, signal stab…

A team of experts for outsourcing your assay developmentsOur Service Team at Cisbio international is highly trained in protein chemistry and fluorescent technology, and offers you its expertise in assay development to build HTRF® assays adapted to your specific targets or to convert existing assays to HTRF® technology.Assays may be developed using HTRF® toolbox reagents, custom labeled molecules or a combination of both. Most…

Cisbio's HTRF® KinEASE™ platform has expanded to include a universal assay for tyrosine kinases. The HTRF KinEASE TK assay is based on our patented HTRF technology and uses a unique tyrosine peptide substrate in combination with a Europium-labeled monoclonal antibody. The HTRF KinEASE™ TK assay has been validated on 59 tyrosine kinases to-date including both receptor and cytoplasmic TKs. A proprietary substrate stabilizing buf…

IP-One ELISA assay kit from Cisbio Bioassays - Simple and highly accurate measurement of IP1 IP1, a downstream metabolite of IP3, accumulates in cells following activation of Phospholipase C (PLC) coupled receptors. Among them, the Gq coupled GPCRs represent the most important family of receptors which can activate the β subtype of the PLC family. Other receptor types, like protein tyrosine kinase receptors, antigen or immuno…

Do you - have trouble finding an assay that fits your needs perfectly or do you want to convert your ELISA into an homogeneous method? Through Assays on demand, Cisbio gives you a list of its latest developments for the Drug Discovery field. To discover the extent of our expertise and know-how, and find a solution to your specific needs, see our service offer.These assays on demand are sold frozen and available in 1,000 and 20…

An acetyl-biotinylated substrate recognized by a Eu3+ anti-acetyl MAb and SA-XL665, which is used in activator screening or to test an High Throughput SIRT1 inhibitor.  The level of enzymatic activity is inversely proportional to the amount of signal produced in the system. For more information please visit Cisbio Bioassays website.