Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
Cas9 Nuclease protein NLS, in complex with guide RNA, offers benefits for CRISPR/Cas9 technology over plasmid or mRNA transfection: Off-target mutations rarely occur Prolonged expression of Cas9 increases off-target editing but RNP delivery is naturally transient Transfection/injection is easy Cas9-NLS bypasses transcription and translation by delivering the protein directly The efficiency of the guide RNA in vit…
Perform MeDIP (Methylated DNA Immunoprecipitation) followed by qPCR to estimate DNA methylation status of your sample using 5-methylcytosine antibody. Our kit contains high quality reagents to get the highest enrichment of methylated DNA with an optimized user-friendly protocol. Characteristics Generate highly consistent results with internal controls in 24h Minimize error with many reagents in 1 tube Optimized pu…
Perform MeDIP (Methylated DNA Immunoprecipitation) followed by sequencing to get DNA methylation status of your sample using 5-methylcytosine antibody and magnetic beads. Our kit contains high quality reagents to get the highest enrichment of methylated DNA with an optimized user-friendly protocol. This package contains everything you need from gDNA extraction to library preparation and quality check. It allows you to perfo…
Assessing the genome-wide chromatin accessibility from individual cells provides unique insights of gene expression regulation for a number of fields such as development, oncology, and neurology. Bio-Rad’s SureCell ATAC-seq provides a fast, robust, and sensitive analysis of the epigenome at single-cell resolution. This method is powered by the combination of both Bio-Rad’s droplet-based microfluidic and a hyperactive Tn5 t…
Single-base resolution CpG detection with our popular Premium RRBS kit (internal bisulfite conversion controls included) Latest technology in bisulfite-seq using Illumina sequencers: > 10x coverage per CpG More than 4 million CpGs detected in human samples As little as 100 ng in mammals, birds, fish ,and more Complete end-to-end service: wet lab to bioinformatics for only 550 per sample!
The Infinium MethylationEPIC Array is a genome-wide DNA methylation analysis technique based on bisulfite conversion and Illumina® technology. It allows to quantitatively detect the methylation level of over 850,000 human CpG positions throughout the genome with single nucleotide resolution. Briefly, upon treatment with bisulfite, unmethylated cytosine bases are converted to uracil, while methylated cytosine bases remain…
Integrative or individual analyses for chromatin with ENCODE standards. End-to-end wet lab service and full ChIP-seq analysis Collaborative and customized project design to meet your needs Dedicated in-house expert Integrative epigenomics data analysis and presentation-ready graphs Expert, extensive bioinformatics
