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Custom cGMP Oligos

Merck

If you commercialize Molecular Diagnostics (MDx), create Laboratory Developed Tests (LDTs), or conduct preclinical research, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards. In the case of oligonucleotide raw materials available with custom specifications, the only option you should consider is Custom cGMP Oligos.

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Sure Blot® Nylon Membrane - Roll

Merck

Sure Blot® Hybridization Membrane is a positively charged nylon membrane for rapid ionic bonding of nucleic acids. Due to its high nucleic acid retention capacity, Sure Blot® can be stripped and reprobed up to 10 times without altering its performance characteristics. A proprietary casting process ensures uniform surface characteristics and lot-to-lot consistency.

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Magna GrIP™ Rack (8 well)

Merck

The Magna GrIP™ Rack is a polyethylene rack containing 4 neodinium magnets. The rack is designed to rapidly and easily pellet samples bound to magnetic particles from the supernatant. In its horizontal position, the rack contains 8 holes suitable for 1.5-2.0 ml tubes or spin columns. The rack is versatile, and may also be used with either 15 ml or alternately, 0.5 ml tubes, simply by standing the rack on either side.

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OxyBlot™ Protein Standard

Merck

OxyBlot™ Protein Standard is composed of five proteins (phosphorylase B, BSA, ovalbumin, carbonic anhydrase, trypsin inhibitor) containing 1-3 dinitrophenylhydrazone (DNP) residues per protein. These attached DNP moieties permit the visualization of the proteins by the detection system of the OxyBlot™ Protein Oxidation Detection Kit. OxyBlot™ Protein Standard serves as an internal control for the electrophoresis, western trans…

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Non-organic DNA Extraction Kit

Merck

DNA Extraction Kit is a simple, non-toxic and efficient way to isolate high molecular weight genomic DNA from a wide variety of mammalian cell sources including: whole blood, body fluids, bone marrow, isolated mononuclear cells, tissue culture cells and solid tissues. Sufficient reagents are supplied for 20 DNA extractions of 2.5-5.0 x 107 cells or 40 DNA extractions of 2.5 x 107 cells. The kit can also be used for apoptotic D…

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Immobilon Transfer Membranes, Sandwiches, and Blotting Filter Paper

Merck

EMD Millipore offers three different Immobilon PVDF membranes, each optimized for different protein blotting applications. We also now offer blotting sandwiches that feature pre-cut sheets of membrane and blotting filter paper.Immobilon membranes provide a number of advantages compared to nitrocellulose. They won’t crack or curl, and they can be cut without fracturing. They also have low background, broad solvent compatibility…

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CpG WIZ® p16 Amplification Kit

Merck

The CpG WIZ® p16 Amplification Kit is used for determining the methylation status of the p16 promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified such that all primer sets in the kit amplify under the same conditions. Control genomic DNA samples (methylated and unmethylated)…

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CpG WIZ® p15 Amplification Kit

Merck

The CpG WIZ® p15 Amplification Kit is used for determining the methylation status of the p15 promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the p15 promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified so that all primer sets in the kit amplify template under the same conditions. Control genomic DNA samples (methylated and unm…

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CpG WIZ® E-Cadherin Amplification Kit

Merck

The CpG WIZ® E-cahedrin Amplification Kit is used for determining the methylation of status of the E-cadherin promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified so that all primer sets in the kit amplify under the same conditions. Control genomic DNA samples (methylated and…

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CpG WIZ® Prader-Willi/Angelman Amplification Kit

Merck

The CpG WIZ® Prader-Willi/Angelman Amplification Kit is used for determining the methylation status of this region by methylation -specific PCR (MSP). The kit contains primers targeted to the CpG island on the SNRPN gene. PCR parameters have been identified such that both primer sets in the kit amplify template under the same conditions. Normal control genomic DNA, which will generate a product with both primer sets, is also i…

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CpGenome Universal Methylated DNA

Merck

CpGenome™ Universal Methylated DNA is enzymatically methylated human male genomic DNA. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) or with amplification primers. It can be used as a methylation-positive control for gene methylation studies.

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CpGenome Universal Unmethylated DNA

Merck

CpGenome™ Universal Unmethylated DNA Set provides 2 separate genomic DNA controls for gene methylation studies. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) and can be subsequently used as an unmethylated DNA control for gene methylation studies.

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CpG WIZ® BRCA1 Amplification Kit

Merck

The CpGenome™ DNA Modification Kit (Cat. No. S7820) contains the reagents necessary to perform the initial bisulfite reactions, while the CpG WIZ® BRCA1 Amplification Kit contains the reagents required for the PCR amplification reactions.

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Direct Detect® Spectrometer

Merck

Introducing Direct Detect™, the first infrared (IR)-based biomolecular quantitation system. Just spot your sample, blank, and read! No sample prep, standard curves, messy cuvettes or liquid waste. With inherent amide bond detection, the Direct Detect™ system distinguishes proteins and peptides from interfering sample components, providing more accurate results without the pitfalls of colorimetric assays. Technology: FTIR Spe…

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MagniSolv™ deuterated solvent

Merck

Indispensable for NMR spectroscopy Unlocking the molecular structure of organic molecules is central to understanding how they interact with other molecules. This is especially critical in genomics, proteomics and drug discovery research. The Nuclear Magnetic Resonance (NMR) technique allows scientists to “see” molecular structure and dynamics. MagniSolv™ deuterated solvents are a key tool for the NMR technique. MagniSolv™ deu…

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PureGenome™ On-Spot Tissue DNA Kit

Merck

The PureGenome™ On-Spot Tissue DNA kit allows for convenient isolation of genomic DNA in any targeted microscopic tissue area on a slide. The system combines a powerful area-specific tissue sampling technology with a one-step DNA extraction method and makes targeted tissue genomic DNA isolation easy and simple. The kit efficiently recovers genomic DNA from paraffin archives or fresh tissue sections for PCR analysis. Unlike a c…

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