Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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MultiScreen Solubility Filter Plates

Merck

96-well filter plate designed and optimized for aqueous solubility assaysDetermining a compound's aqueous solubility has become an essential early measurement to make in the drug discovery process. Poor water solubility can cause problems in many different in vitro testing techniques leading to unreliable results and/or reproducibility problems; insoluble precipitates have been shown to cause false positives in bioassays poten…

4.2/5.0
|3 Reviews

PureProteome™ Magnetic Beads

Merck

Magnetic Bead-Based Isolation of Proteins Millipore’s new PureProteome magnetic beads ensure the rapid and reproducible isolation of proteins. Unlike conventional methods that require centrifugation to pellet the beads then careful aspiration to avoid sample loss, PureProteome magnetic beads are isolated using a magnetic rack. This allows for the total removal of buffers for complete recovery of beads no sample dilution. You…

3.7/5.0
|1 Review

SMCxPRO™ Immunoassay System

Merck

Detect low-abundant proteins at the femtogram/mL level with the sensitivity and speed of the SMCxPRO™ immunoassay system – a powerful, compact and affordably priced protein quantifier. Discovery depends on detection. When the success of your research requires finding and quantifying low-level proteins, you need equipment you can rely on to detect your target.  This compact, benchtop instrument will fit seamlessly into your…

4.3/5.0
|1 Review
  • Best New Life Sciences Product of the Year
  • Life Sciences Product of the Year Award


Fetal Bovine Serum (FBS)

Merck

Take steps to prevent cell death and avoid poor cell growth by sourcing serum from reputable suppliers who can verify quality and origin - like MilliporeSigma.

4.3/5.0
|1 Review


siRNA

Merck

siRNA ranking are listed in order of expected efficacy (1 being the best) as predicted by the Rosetta algorithm. All predesigned siRNA carry the Sigma-Aldrich guarantee. NM_005194 - human NM_024125 - rat NM_009883 - mouse

4.0/5.0
|1 Review

Casein from bovine milk

Merck

Casein from bovine milk is a phosphoprotein. There are four main types of Casein which make up approximately 80% of the total protein in bovine milk: α-s1 Casein, α-s2 Casein, β-Casein, and κ-Casein. Casein is proposed to be the main protective constituent in milk.

3.7/5.0
|1 Review