Merck Products & Reviews

Modulation of gene expression with modified oligos

The VOC Pak is designed to produce water with VOC concentration below the analytical detection limit. VOCs are industrial contaminants that may cause health safety issues and therefore should be detected in the environment. VOCs are routinely analyzed in water, soil, gas and air. Specifications for VOCs in drinking water have been established by different regulatory agencies in many countries.The VOC-Pak cartridge is designed…

Final purification step at the ultrapure water point-of-delivery provides pyrogen- and nuclease-free water at a high flow rate when you need it. The BioPak® unit is a disposable ultrafiltration cartridge typically used in cell culture, biochemistry or molecular biology applications. It can be installed at the outlet of Type I water purification systems such as the Milli-Q®, Direct-Q®, Simplicity® or Synergy® systems, to produ…

The LC-Pak is designed to provide scientists with the certitude that the ultrapure water that they are using in critical organic molecules analysis at trace and ultra-trace levels will be adequate. Recent advances in analytical techniques such as UPLC, LC-MS, LC-MS / MS have considerably improved the sensitivity of organic and biochemical molecule detection. As a result, these techniques now require improved water quality for…

The EDS-Pak is a disposable point-of-use cartridge developed by Millipore to meet the needs of researchers who require ultrapure water free of endocrine disrupters (EDS). The EDS-Pak cartridge contains a specific type of activated carbon that has been validated for the removal of several endocrine disrupters. The cartridge’s housing and connector materials also have been validated for the absence of endocrine disrupters.The E…

A10 TOC Monitor Provides a Complete Picture of Water Purity.

Reliably pure water for results reproducibility & lab productivity

Get the best performance from your water purification system from the people who designed and built it. We provide best-in-class service plans and maintenance options to meet your individual needs. Plus, MyMilli-Q™ Digital Services simplifies system management and allows remote monitoring and support.

Modern-day heroes deserve the authentic Milli-Q ® Ultrapure Experience. The new Milli-Q ® EQ 7000 water purification system delivers consistent quality ultrapure water, ease of use, and agile dispensing. Plus ensure flexibility to adapt to your lab’s changing needs and constraints.

The FRETWorks™ S•Tag™ Assay is a FRET-based method that enables extremely sensitive detection of S•Tag fusion proteins in minutes with a homogeneous format.

CHEMICON's ES Cell Characterization Kit (Catalog number SCR001) is a specific and sensitive tool for the phenotypic assessment of the differentiation status of ES cells by measuring their AP activity, cell-surface stage-specific antigens (SSEA-1, SSEA-4) as well as expression of TRA-1-60, TRA-1-81 antigens.

The ES Cell Marker Sample Kit includes six monoclonal antibodies for the analysis of ES cell marker expression. CHEMICON®'s ES Cell Marker Sample Kit (Catalog number SCR002) contains monoclonal antibodies for the detection of the cell-surface Stage-Specific Embryonic Antigens (SSEA-1, SSEA-3 & SSEA-4), expression of TRA-1-60, TRA-1-81 antigens and Oct-4. This kit permits the phenotypic analysis of the differentiation status of…

EMD Millipore's Alkaline Phosphatase Detection Kit is a specific and sensitive tool for the phenotypic assessment of ES cell differentiation by the determination of AP activity.

EMD Millipore's Mesenchymal Stem Cell Characterization Kit (Catalog Number SCR018) contains a panel of positive and negative selection markers for the characterization of the mesenchymal stem cell population in rat. Positive cell markers include antibodies directed against cell-surface molecules (integrin beta1 and CD54) (Pittenger, M. F., and Marshak, D. R., & Pittenger, M.F., et al.) present on mesenchymal stem cells along w…

CHEMICON®'s Mesenchymal Stem Cell Osteogenesis Kit contains all the reagents necessary to readily differentiate mesenchymal stem cells to an osteogenic lineage as assessed by Alizarin Red staining. Reagents in the kit include two ECM coating molecules (collagen Type I and vitronectin) that have been shown to promote osteogenic differentiation of mesenchymal stem cells (Salasznyk, 2004) along with inducing reagents, dexamethaso…

The Rodent Neuron Differentiation Kit is a system designed for the optimal differentiation of neural stem cells derived from rodents into neurons. Included in the kit are two neural inducers that when added to the Neural Stem Cell Basal Medium allows for the preferential differentiation of rodent neural stem cells to a neuronal lineage. Other components of the kit include reagents for the fixation and two antibodies for the im…

The Pancreatic Islet Cell Characterization Kit (SCR045) provides a convenient set of validated antibodies that allows researchers to reliably identify mature pancreatic islets cells. Along with antibodies generated against discrete hormones secreted by alpha, beta, delta and gamma cells of the pancreatic islets, the kit includes PDX-1 (pancreatic duodenal homeobox gene-1), a master regulator of islet cell development and GLUT-…

Protein A from Staphylococcus aureus has a very high affinity for the Fc regions of IgG molecules. Immoblisation of protein A on beads creates an affinity resin which can be used to purify IgG fractions from crude serum, ascites fluid or cell cuture media.

FOPflash: Transfection grade T cell factor (TCF) reporter plasmid containing two full and one incomplete copy of the TCF binding site (mutated) followed by three copies in the reverse orientation, upstream of the Thymidine Kinase (TK) minimal promoter and Luciferase open reading frame. This plasmid serves as a negative control to TOPflash which contains wild type TCF binding sites.

The H2A.X Phosphorylation Assay Kit (Flow cytometry) is a cell based assay formatted for flow cytometric detection of levels of phosphorylated Histone H2A.X. Cells are cultured in microplates, treated with agents that induce DNA damage or apoptosis, which stimulates H2A.X phosphorylation. Cells are then fixed and permeabilized in preparation for staining and detection. Histone H2A.X phosphorylated at serine 139 is detected by…

TOPglow (TCF reporter plasmid): Transfection grade T cell factor (TCF) reporter plasmid containing four copies of the Tcf binding site (wt) upstream of E1B TATA box and Luciferase open reading frame.

The ApopTag ISOL Fluorescence Apoptosis Detection (DNase Types I & II) technique is based upon the biochemical specificity of the enzymes T4 DNA ligase and Vaccinia Virus DNA Topoisomerase I and the unique, dual labeled, dual hairpin oligonucleotide

The CHEMICON APO-DIRECT™ Kit is a single-step staining method for labeling DNA breaks to detect apoptotic cells by flow cytometry (Li et al. 1995). The kit contains all the reagents required for measuring apoptosis in cells including positive and negative control cells; washing, reaction, and rinsing buffers; and propidium iodide/RNase A solution for counter staining the total DNA.

The MitoLight™ Apoptosis Detection Kit utilizes a lipophilic cation, termed as MitoLight™, as a mitochondrial activity marker. MitoLight™ is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. The monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. MitoLight™ partitions differently i…

The CHEMICON In Situ FLICA Pan-Caspase Detection Kit is a fluorescent-based assay for detection of active caspases in cells undergoing apoptosis. The kit is for research use only. Not for use in diagnostic or therapeutic procedures.