NanoTemper Technologies Products & Reviews

His-Tag specific labeling for MST using RED-tris-NTA

Prometheus Panta monitors the thermal stability, turbidity, and dispersity of a protein sample, and provides the highest-resolution, highest-quality data for ranking and selecting candidates. Prometheus Panta outputs critical quality parameters about your therapeutic proteins of interest, including: their hydrodynamic radius, molecular weight, self-association propensity, and deltaG of unfolding.

Dianthus is a plate-based, microfluidics-free affinity screening platform that measures under controlled equilibrium conditions and in-solution. With two biophysical modalities - Spectral Shift and TRIC - Dianthus excels at challenging interactions that involve molecules like PROTAC ternary complexes, intrinsically disordered proteins, and fragment libraries.

Monolith X is a capillary-based system that enables you to measure the strength of molecular interactions in solution, without the need for immobilization. Minimal impact fluorescent labelling empowers you to measure Kds between a wide variety of targets and ligands using low amounts of sample. Enjoy approachable assay development with a fully guided process embedded in the default software.  

Prometheus Panta + RA monitors the thermal stability, turbidity, and dispersity of a protein sample. It also measures the hydrodynamic radius, molecular weight, and self-association propensity of your protein-based therapeutics for developability profiling. The Panta uses dye-free, buffer-independent measurements from nanoDSF (nano Differential Scanning Fluorimetry), DLS (Dynamic Light Scattering), and backreflection technolo…