Drug discovery > Lead Discovery Products & Reviews

Universal, HTS Kinase Screening Assays Use higher ATP concentrations: Linear response up to 500μM ATP. Use any kinase and kinase-substrate combination, including peptide, protein, lipid, and sugar substrates. Perform the assay without substrate modifications. Obtain reliable results: Z´-factor values routinely >0.7. Reduce false hits: Luminescence is much less susceptible to interference from library compounds t…

The QuantiFluor™ RNA System contains a fluorescent RNA-binding dye that enables sensitive quantitation of small amounts of RNA in solution. Detecting and quantitating small amounts of RNA is a very important step used in many biological applications, particularly in molecular biology techniques. These include measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot anal…

This ready-to-use multimode detection system includes: high-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities.   The GloMax® Discover System is a high-performance multimode detection instrument developed with Promega reagent chemistries to provide a simple means of detecting advanced chemistries. This instrument provides…

The mass spectrometry-compatible yeast and human protein extracts are designed specifically for mass spectrometry applications.   The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC/MS) analysis. Both the yeast and human extracts also are available in an intact undigested form to provide a test material for optimizing mass spec protei…

The GloMax® Explorer System is the newest member of the GloMax® System detection instruments. This multimode reader allows you to get up and running quickly, generating the data you need from your experiments. Simply unpack it, plug it in, and begin your experiments.

Automated Nucleic Acid Purification with Integrated Quantitation

Easy-to-Use, Dedicated Microplate Developed and optimized with our cell and gene reporter assays

Ultrasensitive Single Tube Luminometer Two fluorescence modules available

A Complete Solution for Monitoring LC and MS Instrument Quality Control and Performance. In combination with an accompanying software tool, the 6 × 5 LC-MS/MS Peptide Reference Mix provides a convenient way to assess LC column performance and MS instrument parameters, including sensitivity and dynamic range. Consists of 30 peptides; 6 sets of 5 isotopologues of the same peptide sequence, differing only in the number o…

Measure Chymotrypsin-, Trypsin- and Caspase-Like Activities