Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Exosome Isolation and Studies

BioIVT

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

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RUO and GMP Leukopaks

BioIVT

BioIVT offers high quality, normal and disease state, fresh mobilized and cryopreserved leukopaks, custom collected or sourced from extensive inventory, featuring a diverse donor pool including over 600 HLA-typed recallable, consented donors near biotech hubs in the US and UK.

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Normal and Disease State Tissue

BioIVT

BioIVT’s extensive, highly characterized, normal and disease-state tissue samples are collected and prepared under strict ethical and QC policies and feature detailed clinical data as well as pathologist verification of disease tissue blocks to help ensure the accuracy of your research. Custom collections or extensive inventory are available from a diverse donor pool or any commercially available species.

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In Vitro ADME-Tox Test Systems

BioIVT

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

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Isolated Immune Cells

BioIVT

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

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Clinically-Collected Specimens

BioIVT

BioIVT has the expertise in the processes required for ethical acquisition of biospecimens that cover a wide range of disease states and the protocols needed to produce reliable data. With over 425 IRB-approved clinical sites, BioIVT provides clinical specimens for nearly all disease states.

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Blood, Plasma and Serum

BioIVT

BioIVT supplies high quality, ready to ship or custom plasma, serum, and whole blood—both normal and disease-state—collected from a diverse pool of consented donors under IRB-approved protocols or a wide variety of species.

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Neuroscience Research Specimens

BioIVT

As the world's largest private repository of human cerebrospinal fluid, BioIVT’s Center for NeuroExcellence offers 35,000+ healthy and 113,000+ diseased donor samples allowing for comparative studies and precise control matching. The samples are ethically collected following strict quality standards and feature detailed clinical data and matching blood, plasma, or sera.

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In Vitro ADME/DMPK Studies

BioIVT

With decades of drug metabolism, drug-drug interactions (DDI) and related expertise, BioIVT’s experts can provide you with the right studies to understand the properties and potential risks of your compound when it’s most critical for your program.

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Target Sufficiency

Inotiv

Target Sufficiency® is the ability of a target system to respond to a therapeutic. It reflects the abundance and forms of the drug target protein, as well as other key system proteins that connect the target to disease phenotypes and enable response. Assessment of the target system requires an analysis platform that can simultaneously capture multiple precise protein measurements.

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eXTReme™ FoilSeal™ Microplate Sealing Film for PCR and Long-Term Storage, Light Sensitive Assays & Robotics

Excel Scientific, Inc.

A 48 um soft non-permeable aluminum foil sealing film with 30 um layer of strong acrylic adhesive. FoilSealTM sealing foils remove cleanly from plate surfaces with no adhesive stringing, residue or contamination. Each sealing foil measures 78.3 x 129 mm and offers sufficient sealing area for all plate types (e.g. flat top and raised-rim). Chamfered corners result in no plate overhang for robotics applications. Features one end…

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ThermalSeal™ RTS, Optically Clear, Silicone Adhesive Microplate Sealing Film for Real-Time PCR

Excel Scientific, Inc.

The encapsulated silicone adhesive is non-tacky until pressed against the sealing surface, at which time adhesive is released only in sealing areas to form the strongest available heat-resistant seal around each well on the plate. Adhesive on non-sealing areas of the film, such as directly over sample wells, remains encapsulated and inert. Excel ThermalSeal RTS films are sized to fit within the edges of raised-rim 96-well plat…

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X-Pierce™ Microplate Sealing Film for Automation

Excel Scientific, Inc.

X-PierceTM sealing films are 89 µm thick vinyl with a 18 µm thick adhesive layer, designed for temporary protection from contamination and evaporation for samples in 96-well plates. A precut "X" over each well creates four flaps that easily bend downward when pushed by a robotic probe or pipet tip, allowing sample access without coring or adhesive fouling. A thin adhesive layer and special hairline cuts separating the X-Pierce…

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AeraSeal™ Microplate Sealing Film for Cell & Tissue Culture

Excel Scientific, Inc.

A 140 µm thick hydrophobic porous rayon sealing film including medical-grade adhesive for tissue culture plates, bio-blocks, and 96-well plates where gas exchange is necessary for cell or bacterial growth. AeraSeal sealing films minimize cross-contamination, spillage and evaporation. They allow uniform air and CO2 exchange for all wells, unlike plate lids which favor exchange for wells near the plate edges. Dimensions: 82.6 by…

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SealMate™ Starter Kit with SealPlate Elisa/Storage Film

Excel Scientific, Inc.

Excel Scientific's unique SealMate™ system provides a convenient new method for sealing standard-format microplates with adhesive films. The system includes a molded polypropylene dispenser with a hinged “clamshell” design and sealing films supplied in a novel sheeted-roll configuration.Features:environmentally friendly green product: no protective backing to remove and discardconvenient, easy film application for microplatest…

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SealMate™ Starter Kit with AeraSeal Breathable Film

Excel Scientific, Inc.

Excel Scientific's unique SealMate™ system provides a convenient new method for sealing standard-format microplates with adhesive films. The system includes a molded polypropylene dispenser with a hinged “clamshell” design and sealing films supplied in a novel sheeted-roll configuration.Features:environmentally friendly green product: no protective backing to remove and discardconvenient, easy film application for microplatest…

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AeraSeal™ Film in Roll-Seal™ Format for Automated Sealers

Excel Scientific, Inc.

Excel Scientific now offers adhesive sealing films on Roll-Seal™ rolls for use with high-throughput automated microplate sealers. Film rolls, constructed on three-inch-diameter plastic cores, are compatible with most common adhesive sealers (Brandel, Thermo-Fisher/Abgene, FluidX, KBiosystems). The Roll-Seal format provides reliable and efficient sealing at a lower cost per plate with minimal user intervention. Robust static-fr…

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AlumaSeal™ Film in Roll-Seal™ Format for Automated Sealers

Excel Scientific, Inc.

Excel Scientific now offers adhesive sealing films on Roll-Seal™ rolls for use with high-throughput automated microplate sealers. Film rolls, constructed on three-inch-diameter plastic cores, are compatible with most common adhesive sealers (Brandel, Thermo-Fisher/Abgene, FluidX, KBiosystems). The Roll-Seal format provides reliable and efficient sealing at a lower cost per plate with minimal user intervention. Robust static-fr…

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ThermalSeal RTS™ Film in Roll-Seal™ Format for Automated Sealers

Excel Scientific, Inc.

Excel Scientific now offers adhesive sealing films on Roll-Seal™ rolls for use with high-throughput automated microplate sealers. Film rolls, constructed on three-inch-diameter plastic cores, are compatible with most common adhesive sealers (Brandel, Thermo-Fisher/Abgene, FluidX, KBiosystems). The Roll-Seal format provides reliable and efficient sealing at a lower cost per plate with minimal user intervention. Robust static-fr…

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SealPlate® Microplate Sealing Film for ELISA, EIA, Incubation & Storage, Sterile

Excel Scientific, Inc.

SealPlate® 50 µm thickness polyester sealing films minimize evaporation, prevent spillage and contamination between wells, and provide a secure seal, not just a cover. Secure sealing of all wells eliminates "edge effects" in sensitive ELISA assays. SealPlate sealing films can also be used with tissue-culture plates for short-term storage, incubation, and containment of biohazards. SealPlate sealing films are non-pierceable. Ea…

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