Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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TB Green Premix Ex Taq II (Tli RNase H Plus)

Takara Bio

This Takara Bio SYBR Green Master Mix is recommended for real-time PCR (qPCR) when high specificity is critical, because this reagent effectively suppresses amplification of primer-dimers and off-target products. Use this product when primer design has been optimized, but an increase in specificity of the qPCR assay is still needed. SYBR Premix Ex Taq II (Tli RNase H Plus) includes SYBR Green I, a reagent designed for interca…

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iMScope TRIO

Imaging Mass Spectrometry identifies what you see at the molecular level iMScope TRIO transforms your data from just "Observation" to "Analysis". The instrument is a combination of an optical microscope which allows the observation of high-resolution morphological images, with a mass spectrometer which identifies and visualizes the distribution of specific molecules. Superimposing the two images obtained based on these very d…

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CleanLaze

B&W Tek, Inc.

The CleanLaze® spectrum stabilized laser system is a narrow, spectral linewidth laser available in both OEM and end-user configurations. The CleanLaze® spectrum stabilized laser system is a narrow, spectral linewidth laser available in both OEM and end-user configurations. Specifically suited for Raman spectroscopy, it offers a hermetically sealed laser component integrated with a laser and a driver. The compact,rugged packag…

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FAM FLICA® Caspase 1 Assay Kit

Immunochemistry Technologies LLC

Detect caspase-1 activity with the FLICA® Caspase 1 Assay Kit. This in vitro assay employs the green fluorescent inhibitor probe FAM-YVAD-FMK to label active caspase 1 enzyme in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry. Caspase 1 (ICE):Members of the mammalian caspase family of cysteinyl aspartate-specific proteases play disti…

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Magic Red™ Caspase 3 & 7 Assay Kit

Immunochemistry Technologies LLC

Magic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…

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RetroNectin® Reagent

Takara Bio

Research and Clinical Grade RetroNectin Reagent for Retroviral or Lentiviral Transduction. RetroNectin Reagent for retroviral or lentiviral transduction significantly increases transduction efficiency and results in enhanced gene transfer, especially in suspension and hematopoietic stem cells. RetroNectin Reagent is a chimeric peptide composed of E. coli-derived recombinant human fibronectin fragment that contains three funct…

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Mouse ROSA26 safe harbor gene knock-in kit and clones

GeneCopoeia

Mouse ROSA26 safe harbor gene knock-in kit and clones. ROSA26 (also known as ROSAβgeo26 locus) in mice genome is first found in chromosome 6 in one particular strain of mice-named ROSAβgeo26-expressed β galactosidase from a randomly inserted transgene at high levels uniformly in nearly all tissues examined. This locus expresses one coding transcript and two noncoding transcripts, and only the non-coding transcripts are disrup…

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Flow Cytometer Calibration Beads

Takara Bio

Flow Cytometer Calibration Beads for AcGFP/EGFP and mCherry. Use these beads to calibrate your flow cytometer prior to analyzing cells that express the AcGFP1 or mCherry fluorescent proteins. The AcGFP Flow Cytometer Calibration Beads allow for easy calibration of any flow cytometer with a 488 nm laser line that excites the green fluorescent proteins AcGFP1 (Aequorea coerulescens GFP) and EGFP. [The AcGFP Flow Cytometer Calib…

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Thermo Scientific KingFisher Pure Kits

Thermo Fisher Scientific

The Thermo Scientific KingFisher Pure Kits are specially designed for use with the KingFisher nucleic acid purification system. These optimized reagent kits help you achieve rapid, high-quality results for a variety of applications – with minimal effort. KingFisher Pure Kits are now available for Cell and Tissue DNA, DNA Blood, DNA Plant, Plasmid, RNA Blood, RNA Plant, RNA Tissue, and Viral NA.Key Features: Developed spec…

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PureFlex™ process container film

Merck KGaA, Darmstadt, Germany

Designed to provide strength, flexibility (with maximum resistance to flex-crack), excellent gas barrier performance and inert contact. PureFlex™ Single-use process container films are flexible, robust and chemical resistant materials used in the construction of our single-use process containers, including Mobius® assemblies and NovaSeptum® sterile sampling products.PureFlex film is a high purity, medical grade, coextruded fi…

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CRISPR-Cas9 Custom Services

GeneCopoeia

GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…

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U-SPECT4 CT

MILabs BV

By far the best available SPECT resolution and sensitivity on the market. Patented 3D focusing capability for dynamic nuclear microscopy in organs and tumors. Ultra-fast imaging with multi-physiologic gating reveals dynamic processes with unprecedented time resolution, ideal for pharmacokinetic imaging.Patented M5™ collimation satisfies widest range of resolution, sensitivity and FOV needs. High reliability and long life due…

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Tissue-Tek® AutoSection® Automated Microtome

Sakura

Precision sectioning and consistent high quality, is now achievable for every technician, every single block and tissue type. The Tissue-Tek® AutoSection® automatically aligns, trims and sections your blocks, including Tissue-Tek® Paraform®. The combination of cutting edge technology and razor sharp Accu-Edge® Microtome Blades enables thin, consistent high quality sections. AutoAlign™ technology will precisely orient blocks a…

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ChIPettor™ System

Diagenode

The ChIPettor™ System has everything you need for high-quality, fast, and easy chromatin immunoprecipitation for either histones or transcription factor ChIP. Contains a full set of reagents for start-to-finish ChIP starting with 100,000 to 1,000,000 cells (ideal for histone pull down), purification reagents, and a semi-automated pipettor with special resin pipet tips. The ChIPettor™ is designed to stand independently on a 9…

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DEXPAT Reagent

Takara Bio

DEXPAT Reagent from Takara Bio is designed for one step DNA extraction from paraffin embedded tissue fixed in 10% formalin. DEXPAT Reagent eliminates the laborious deparaffinization, organic solvent extraction and enzymatic digestion steps required in most standard DNA extraction protocols. Furthermore, DEXPAT Reagent enables preparation of PCR-ready DNA in only 25 minutes versus 2-3 days using conventional DNA extraction met…

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EpiScope MSP Kit

Takara Bio

The EpiScope MSP Kit features a reagent designed exclusively for DNA methylation analysis via methylation specific PCR (MSP). This reagent contains a specific enzyme in an optimized buffer, allowing MSP analyses on bisulfite-treated uracil-containing DNA templates. This kit features high amplification efficiency and methylation specificity compared with standard PCR. The EpiScope MSP Kit is optimized for real-time monitoring…

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SMART cDNA Synthesis Kits

Takara Bio

SMART (Switching Mechanism at 5’ End of RNA Template) is a unique technology that allows the efficient incorporation of known sequences at both ends of cDNA during first strand synthesis, without adaptor ligation. The presence of these known sequences is crucial for a number of downstream applications including amplification, RACE, and library construction. While a wide variety of technologies can be employed to take advantag…

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