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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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ProteoSave™ Low Bind 96F Plate

S-Bio

Protein Low-binding Labware PROTEOSAVE™ series offer unique advantage over regular polypropylene or polystyrene tubes in reducing sample loss by preventing non-specific binding of sample (proetins, peptide, cells) to the plastic surface.

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PE/Cy7 Annexin V

BioLegend

Available in 25, 100 or 300 test packs. Annexin V (or Annexin A5) is a member of the annexin family of intracellular proteins that binds to phosphatidylserine (PS) in a calcium-dependent manner. PS is normally only found on the intracellular leaflet of the plasma membrane in healthy cells, but during early apoptosis, membrane asymmetry is lost and PS translocates to the external leaflet. Fluorochrome-labeled Annexin V can t…

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Chromatrap® DNA Extraction

Chromatrap

The Chromatrap DNA Extraction kit delivers a protocol to isolate superior quality DNA from a wide range of samples sources, including difficult cell and tissue types. With high volume binding capacity, DNA is efficiently lysed, captured and eluted from the unique spin column and 96 well plate designs. Quick and easy to use, the Chromatrap DNA Extraction kit ensures high quality and recovery of DNA during the first steps of fun…

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Chromatrap® Gel Purification

Chromatrap

The Chromatrap Gel Purification Kit contains spin columns and reagents to quickly and efficiently purify DNA from agarose gels. Elute high yield and ultra-pure DNA for downstream molecular biological applications.

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Chromatrap® DNA Size Selection

Chromatrap

Easily purify your preferred DNA fragments from a wide range of sample sources with the Chromatrap Size Selection kit. In 3 simple steps (bind, wash and elute) in under 5 minutes, elute superior quality DNA fragments of your desired size for downstream applications such as library preparation for next generation sequencing in under 5 minutes.

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Mixed Cortical Neurons

BrainXell

BrainXell's Mixed Cortical Neurons include glutamatergic neurons and GABAergic neurons that have been independently derived from iPSCs. Following generation of the highly pure cortical neurons, a mixture of 80% glutamatergic and 20% GABAergic neurons is created to mimic the ratio found in many regions of the cortex.

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AAV5 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 5. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK5a antibody is used as capture and detection antibody in the AAV5 Titration ELISA (PRAAV5). Academic discount available on request.

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AAV9 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV9 wt virions, AAV9 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 9. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK9 antibody is used as capture and detection antibody in the AAV9 Titration ELISA (PRAAV9). Academic discount available on request.

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Phage Titration ELISA

PROGEN

Kit allows fast titration of M13 particles by immunological recognition of protein VIII. Contains standard M13 titrated by electron microscopical method.

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AAV1 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 1. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.

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AAV6 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV6 wt virions, AAV6 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 6. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.  

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Baculo Expression Vector pAc-kappa-Fc

PROGEN

Baculovirus cassette vector pAc-kappa-Fc for the expression of human, humanized or chimeric IgG(kappa) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Baculo Expression Vector pAc-lambda-CH3

PROGEN

Baculovirus cassette vector pAc-lambda-CH3 for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain scFv antibody gene fragments.

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Baculo Expression Vector pAc-lambda-Fc

PROGEN

Baculovirus cassette vector pAc-lambda-Fc for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Human IgG / IgM Library Primer Set

PROGEN

PCR oligonucleotide primer sets consisting of 16  primers  for amplification and 16 primers  for cloning of human IgG and IgM heavy and light chain variable domain coding regions for generating universal, patient or antibody-specific scFv phage-display libraries. 

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Mouse IgG Library Primer Set

PROGEN

PCR oligonucleotide primer sets consisting of 25 primers for amplification and 25 primers for cloning of mouse IgG heavy and light chain variable domain coding regions for generating universal or antibody-specific scFv phage-display libraries.

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pOPE 101 Expression Vector

PROGEN

Cassette vector for the expression of functional recombinant single-chain Fv antibody fragments in Escherichia coli. Cloning of heavy and light chain variable domain genes of Fv antibody fragments selected from hybridomas, single B-lymphocytes or phage display libraries. Discover more about the hyperphage system here.

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