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Monoclonal Anti-Vinculin antibody produced in mouse

Merck KGaA, Darmstadt, GermanyV9131Available: Worldwide

clone hVIN-1, ascites fluid  

Merck KGaA, Darmstadt, Germany

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Monoclonal Anti-Vinculin (mouse IgG1 isotype) is derived from the hVIN-1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from immunized BALB/c mice. Vinculin is localized in the fascia adherens of the intercalated disk (cardiac muscle), myotendinous junctions (skeletal muscle), neuromuscular junctions and the membrane-associated dense bodies of smooth muscle. In many cell types undergoing viral transformation, vinculin becomes redistributed to rosettes or podosomes.

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