Drug discovery > Basic Research Products & Reviews

Purify High-Quality, Intact Nucleic Acids from FFPE Tissue WithoutHarsh Solvents or Overnight Digestions.

Ethanol-Free Purification for High-Quality gDNA Every Time

Quick, easy, phenol-free miRNA isolation from cells and tissues

The Wizard® SV 96 and SV 9600 Plasmid DNA Purification Systems provide a simple and reliable method for the rapid isolation of plasmid DNA using a silica-membrane, 96-well, high-throughput format. A single plate can be processed in 60 minutes or less. The purified plasmid can be used directly for automated fluorescent DNA sequencing as well as for other standard molecular biology techniques, including restriction enzyme digest…

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

The small size and bright luminescence of NanoLuc® luciferase bring exquisite sensitivity to many applications. From NanoBRET™ technology, a BRET-based method to study protein:protein and protein:small molecule interactions, to NanoLuc® Binary Technology (NanoBiT), NanoLuc is the cornerstone for studying genetic responses and protein dynamics in cells at physiologically relevant levels. The flexibility of NanoLuc® technologies…

High-Throughput Extraction of DNA from FFPE Samples Robust, precipitation-free protocol, no chance of lost pellets High yields of pure DNA from FFPE samples without using xylene or other hazardous chemicals Ideal for use in downstream applications including qPCR and next-generation sequencing (NGS)

The Wizard MagneSil Tfx™ System provides a simple, rapid method for isolating transfection-quality plasmid DNA in a 96-well, high-throughput format. The use of paramagnetic particles for lysate clearing as well as DNA capture circumvents the need for centrifugation or vacuum manifolds, allowing DNA purification to be completely automated.

The SV 96 Total RNA Isolation System provides a high-throughput technique to prepare intact RNA from tissue and cultured cells. Total RNA can be purified from 96 samples in less than an hour without centrifugation. The system incorporates a DNase treatment step that is designed to substantially reduce genomic DNA contamination, which can interfere with amplification-based methodologies. Purification is achieved without phenol:…