Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that are commonly comprised of four structural proteins. One of the proteins, SARS-CoV-2 Spike Protein (S Protein), is a glycoprotein that mediates membrane fusion and viral entry, and as such is a crucial COVID-19 target. R&D Systems SARS-CoV-2 Spike range of bioactive proteins are valida…
CHO expressed. GCN4-IZ trimerization domain. Prefusion Conformation. High ACE-2 binding
UK Variant. Resistant to Furin & Stabilized Prefusion Conformation
Agilent Bio-Monolith Protein A LC columns are designed for analytical separation of most of IgG subclasses (human and mouse). It delivers fast and accurate quantitation of mAb titer and purification of small amounts of mAb for further characterization. These monolithic column enables extremely fast separations to speed up method development time and decrease costs. They are compatible with HPLC and UHPLC systems.
The 1260 Infinity II Prime Online LC System is a process analysis system enabling automated process monitoring, providing real-time data for greater control and faster understanding of processes.
The 1260 Infinity II Online Sample Manager is an online sampling module that connects the analytical world with the process world. The module provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, as well as upstream bioreactors and downstream purification devices.
Bioinformatics and Protein Array Services
Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.
Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…
The 1260 Infinity II Prime Bio LC System is a versatile HPLC for bioseparations and offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.
The 1290 Infinity II Bio High-Speed Pump is a binary UHPLC pump consisting of biocompatible material for use in biopharma and other applications utilizing high salt and extreme pH conditions. It uses high-pressure blending from up to two solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.
The 1260 Infinity II Bio Flexible Pump is a UHPLC pump comprising biocompatible components, developed for biopharma applications and for other analyses requiring high-salt and extreme-pH conditions. This pump enables quaternary solvent delivery at pressures up to 800 bar and flow rates up to 5 mL/min.
The 1290 Infinity II Bio Multisampler, with its biocompatible sample flow path, is perfectly suited for biomolecule analysis, ensuring integrity of biomolecules and minimizing unwanted surface interaction. For temperature-sensitive samples, a compressor-based thermostatting device can be added.
(6aR,9R)-Δ10 -THC (CRM) (Item No. 33011) is a certified reference material that is structurally similar to known phytocannabinoids and has been found as a byproduct in Cannabis processing. It is regulated as a Schedule I compound in the United States and is provided as a DEA exempt preparation. Also available are (6aR,9S)-Δ10 -THC (CRM) (Item No. 33012), 9(R)-Δ6a,10a -THC (CRM) (Item No. 33013), and 9(S)-Δ6a,10a -THC (CRM) (I…
Looking to Replace REACH-Restricted NMP? Go Green!
Phytocannabinoid Mixture 8 (CRM) (Item No. 34043) is a certified reference material mixture that contains neutral, non-acid, forms of compounds that can be isolated from plants in the genus Cannabis. Included are Δ9-THC, Δ8-THC, cannabinol, cannabidiol, (±)-cannabichromene, cannabidivarin, cannabigerol, and tetrahydrocannabivarin. It is provided as a DEA exempt preparation in an amber ampule in which the headspace has been p…
AdvanceBio Peptide Plus columns are reversed phase, superficially porous particle LC columns optimized for the separation of target peptides, impurities, and post translational modifications.
Uv-Vis double beam scanning spectrophotometer with 1nm bandpass
UV-Vis double beam scanning spectrophotometer with GMP compliancy
