Drug discovery > Lead Discovery Products & Reviews

A range of 0.01 to 50 ml/minute, used to create a high pressure mixing gradient.

SR7500DC pushes the limits of detection and sensitivity in label-free interaction analysis.

The Atlas chromatography data system controls hundreds of instruments from a variety of vendors in compliance with FDA regulations, including 21 CFR Part 11. Atlas was developed in partnership with leading chromatographers to easily configure to any laboratory’s workflow while providing the flexibility to integrate with LIMS and other data management systems for a scalable, compliant solution. The Atlas chromatography data sy…

Autoclavable caps that are designed to ensure the ultimate in product safety. The liners are made of a nontoxic white styrene-butadiene rubber and are faced with Teflon®, which offers excellent chemical resistance. Models available in range are the; • 13-425 Black Phenolic Cap with TFE Liner • 15-425 Black Phenolic Cap with TFE Liner • 22-400 Black Phenolic Cap with TFE Liner • 24-400 Black Phenolic Cap with TFE Liner For mor…

Versatile polymeric material for retention of polar and non-polar analytes • Exceptional recoveries for polar and non-polar analytes • High and consistent recoveries • High capacity material • Fast and easy sample preparation method development • pH stable 0-14 HyperSep Retain PEP (polar enhanced polymer) is a high purity, highly porous polystyrene DVB material modified with urea functional groups to give balanced retention of…

Septa are an important part of the GC instrument, providing a leak-free seal at the inlet, and require good durability, resealability and low bleed to optimize the performance of your instrument.Septa from Thermo Fisher Scientific are available in several types of materials, described below, to fit Thermo Fisher Scientific's GC and GC/MS instruments as well as other manufacturers’ instruments, matching different application ne…

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Transcription Factors and related genes reformatted onto an OpenArray plate. Kit includes: Open…

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Mouse Inflammation and related genes reformatted onto an OpenArray plate. Kit includes: OpenArr…

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Mouse Transcription Factors and related genes reformatted onto an OpenArray plate. Kit includes…

HPLC Columns

The EPSON RS robots are a unique new SCARA design built to reduce cycle times and maximize work envelope usage. By designing the arm so that Joint 2 can go under Joint 1, the RS3 utilizes the entire workspace underneath the arm. There is no dead space as with other SCARA models. This allows the RS3-351 model to work on pallets as large as 494mm x 494mm. A size which normally requires a 700mm SCARA arm or larger. Speed - Ne…

Mr. M software facilitates targeted proteomics experiments by assisting during design, data collection, and result visualization. The software supports a new, more flexible targeted proteomics technique by using mass spectrometry.

The Accela PDA is optimized for the detection of high speed chromatographic separations. The short 1 cm path length, combined with the incredibly minimized cell volume of 2 μL, renders this LightPipe flowcell as the premium choice for fast separations. The extremely low level of dispersion in the LightPipe enables the flowcell to retain the excellent peak shape and chromatographic resolution from the column. Patented LightP…

The Accela 600 LC pump offers a maximum operating pressure of 600 bar and involves the use of unique and innovative Force Feedback Control (FFC), enabling the delivery of accurate and precise flow and gradients under all operating conditions. This pump is able to deliver unmatched compositional and flow rate accuracy and precision over the entire operating range resulting in exceptional reproducibility. Designed for configurat…

The Accela 1000 LC pump offers a maximum operating pressure of 15,000 psi and involves the use of unique and innovative Force Feedback Control (FFC), enabling the delivery of accurate and precise flow and gradients under all operating conditions. This pump is also able to deliver unmatched compositional and flow rate accuracy and precision over the entire operating range resulting in exceptional reproducibility making it an un…

Thermo Scientific Online SPE Products have been designed to clean-up and concentrate target analytes in minutes. The products are available in different formats and utilize popular HyperSep SPE materials such as the HyperSep™ Retain polymeric range of materials and HyperSep Hypercarb™ for polar analyte retention.

Symbiosis™ Pharma is Spark Holland's unique solution for integrated online SPE-LC-MS automation (XLC-MS). The heart of the matter in XLC-MS, is where the autosampler injects at a controlled temperature, raw bio-fluids directly on a fresh disposable SPE cartridge. The small particle sorbent assures a clean extract, a very high sensitivity and reliable results. Online elution to the LC-MS cuts the number of sample prep steps in…

A new member of the HyPURITY® family introduced at Pittcon 2003, HyPURITY AQUASTAR™ columns are a new silica-based polar end-capped C18 which is designed to offer superior retention of polar compounds and increased sensitivity in 100% aqueous conditions. The robust nature of the bonded phase results in a silica-based column that is unsurpassed for LC and LC/MS applications. This next generation column also offers enhanced perf…

The Vision diode array spectrophotometer offers 16 predefined methodologies for nucleic acid quantification (DNA, RNA, and oligonucleotides), protein assays (BCA, Biuret, Bradford, and Lowry) and for cell culture density measurements. Additionally, the Vision can accomodate up to 90 custom protocols. The visualization of the nucleic acid scan with the full graphic display is particularly useful, especially for RNA samples wh…

The ASIC1a gene encodes the pore-forming subunit of a proton-gated, non-selective cation channel. ASIC1a channels expressed in neurons are therapeutic targets for treatment of pain and depression. Synonyms: Acid-sensing (proton-gated) ion channel Host cell: CHO-K1, division-arrested Gene name: ACCN2 Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 ce…

The ACCN1 gene encodes the pore-forming subunit of a proton-gated, non-selective cation channel. ASIC2a channels expressed in neurons are therapeutic targets for treatment of pain. Synonyms: Acid-sensing (proton-gated) ion channel Host cell: CHO-K1, division-arrested Gene name: ACCN1 Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 cells total) Growt…

The ACCN31 gene encodes the pore-forming subunit of a proton-gated, non-selective cation channel. ASIC3 channels expressed in neurons are therapeutic targets for treatment of pain. Synonyms: Acid-sensing (proton-gated) ion channel Host cell: CHO-K1, division-arrested Gene name: ACCN3 Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 cells total) Growt…

Human Cav2.2/β3/α2δ1 ion channel-expressing, division-arrested cells (CHO-K1). Cat#: CT4159. Three vials of Cyropreserved irradiated cells, 2x10E6 cells/vial (6x10E6 cells total). Platform validation: PatchXpress®

The human CACNA1B gene encodes the pore-forming subunit of voltage-gated N-type Ca2+ channels. Co-expression with the β3 and α2δ1 auxiliary subunits recapitulates function in heterologous expression (CHO cells). Cav2.2 channels, widely distributed in neurons, are therapeutic targets in neuropathic and inflammatory pain. Synonyms: N-type calcium channel Host cell: CHO-K1, division-arrested Gene name: CACNA1B/CACNB3/CACNA2D1 My…

The HCN4 gene encodes the pore-forming subunit of a hyperpolarization-gated, cyclic nucleotide-sensitive, non-selective cation channel. HCN4 channels expressed in the heart contribute to the pacemaker current (Ih) and are therapeutic targets for treatment of cardiac ischemia and angina. Synonyms: hyperpolarization-activated, cyclic nucleotide-gated channel Host cell: CHO-K1, division-arrested Gene name: HCN4 Mycoplasma status…