Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
Cisbio's cAMP HiRange kit is designed to address either the use of cell-based and cellular membranes-assays in GPCR activation and Adenylate Cyclase activity screening. The cAMP HiRange assay is highly robust and produces quality results while eliminating the need for a continuous supply of living cells.
IP1, a downstream metabolite of IP3, accumulates in cells following Gq recepetor activation and is stable in the presence of LiCl making it an ideal GPCR (Gq) functional assay. Cisbio developed and patented a highly accurate HTRF assay for measuring IP1 in 96-, 384- and 1536-well formats providing for a HTS compatible assay.
Cyclic GMP (Guanosine 3',5'-cyclic monophosphate) is a major second messenger that mediates cell activities by activating protein effectors such as protein kinase G (PKG), cGMP-regulated phosphodiesterases (PDEs), and cGMP-gated channels. Cellular cGMP is synthesized by soluble Guanylyl Cyclases and particulate Guanylyl cyclase, triggered by nitric oxide and atrial natriuretic peptide (ANP) binding respectively. Key processes…
Minimal Training - Easy to Use The large liquid-crystal display (LCD) has been incorporated with easy to follow prompts, large fonts, and graphics to help reduce the time needed to get your results. The description on the instrument's soft keypad quickly guides you through specific programs. Mighty Performance with Quantitative Methods Everything from simple concentration measurements up to sophisticated quantitative calibrati…
High Sensitivity The SolidSpec 3700/ 3700DUV is designed for the highest sensitivity. It is the first UV-VIS-NIR spectrophotometer with three detectors: a photomultiplier tube (PMT) detector for the ultraviolet and visible region, and furthermore InGaAs and PbS detectors for the near-infrared region. The use of the InGaAs and PbS detectors makes the sensitivity in the near-infrared region extremely high. Up to now, all convent…
SWING: automated reaction and sample preparation The Chemspeed‘s SWING is designed for high throughput automation of substance handling tasks. The instrument‘s unique design accommodates several tools that can be automatically exchanged during a run. The availability of both a solid dispensing unit and a 4-needle liquid handling unit on the same platform enables highly efficient, accurate and precise dispensing of more than 9…
SWEIGHER: for automated weighing, capping, crimping, de-capping The Chemspeed SWEIGHER automates all of the steps for you: - Tares each vial - Dispenses liquid and solid compounds - Caps and crimps the vials - Transfers each vial sequentially to the balance - Offers optional barcode identification - Weighs each vial - Acquires and stores data in your database Benefits:- Eliminate tedious manual filling and weighing, and pro…
ASW2000: Automated synthesis workstation The ASW platform enables you to do automated and unattended synthesis integrating work-up and analysis during or at the end of the synthesis. 1. Transfer your chemistry to an automated synthesizer without restrictions or compromises: reactors in glass (maximum temperature range) and reagent handling under completely inert conditions. 2. Automated and unattended synthesis with complet…
AutoPlant / MultiPlant: Solutions for Process R&D, Polymer Synthesis and Preparative Synthesis The Chemspeed MultiPlant and AutoPlant workstations offer targeted solutions for Process R&D, Polymer Synthesis and Preparative Synthesis. The leading edge MiniPlant technology allows scientists to truly mimic the final industrial production process and provides all the required flexibility to optimize integrated reaction sequences,…
Determining the Carbon, Hydrogen, Nitrogen, Oxygen, and Sulphur (CHNS-O) content of unknowns is one of the most basic and essential needs of any chemist. Clarity Elemental Analysis Software is based on proven Clarity Chromatography Software. This solution provides a simplified version of the Clarity user interface that speeds up the workflow with elemental analyzers equipped by autosamplers. Clarity Elemntal Analysis Softwar…
