Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.
These Corning® syringe filters have polypropylene copolymer housings, female Luer lock inlets and male Luer slip outlets. Regenerated cellulose (RC) membranes are the best choice for DMSO compatibility. 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards
Minimizes unnecessary transfers by filtering directly into 50 mL centrifuge tube. Includes two centrifuge tube stands with each case. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Polypropylene centrifuge tube is supplied with an individually wrapped cap for storage. Individually packaged, sterile, certified nonpyrogenic. Expiration date a…
Corning® 500 mL Bottle Top Vacuum Filter, 0.22 µm Pore 33.2cm2 PES Membrane, Fits 33mm Diameter Necks, Sterile, 12/CaseFits plastic or glass media bottles with 33mm neck sizes.Polyethersulfone (PES) membranes provide the fastest flow rates, the lowest protein binding and low extractables and are best for filtering cell culture media.Angled hose connector simplifies vacuum line attachment.Individually packaged, sterile and cert…
Fits plastic or glass media bottles with 45mm neck sizes. Polyethersulfone (PES) membranes provide the fastest flow rates, the lowest protein binding and low extractables and are best for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded…
Cell viability and cytotoxicity detection. Colourimetric microplate assay, one solution type, no washing required, no radioisotopes or organic solvents required.
These Costar® Spin-X® centrifuge tube filters have a 0.22 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Sterile and certified nonpyrogenic and DNase-/RN…
DNASpace provides a very flexible environment for creating custom bioinfomatics workflows. The beauty of this program is that you can tailor these workflows for both high throughput and specialized complex analyses. DNASpace allows you to perform several different analytical protocols simultaneously. For example, you can analyze a group of DNA fragments by performing a local BLAST search with a database on your server and perf…
Fits plastic or glass media bottles with 45mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…
The Jouan RC10 series of vacuum concentrators/centrifugal evaporators offers a wide range of product protection features allied to rapid and safe concentration of heat-labile samples. The RC10 modules can be combined with oil-free or high vacuum pumps, a choice of cold traps and a wide selection of rotors (eliminating sample loss by transfer), ensuring solvent recovery and sample concentration in the minimum time. Product d…
Minimizes unnecessary transfers by filtering directly into 50 mL centrifuge tube. Includes two centrifuge tube stands with each case. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Polypropylene centrifuge tube is supplied with an individually wrapped cap for storage. Individually packaged, sterile, certified nonpyrogenic. Expiration date a…
These Costar® Spin-X® centrifuge tube filters have a 0.45 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Sterile and certified nonpyrogenic and DNase-/RN…
These Corning® syringe filters have acrylic copolymer housings, female Luer lock inlets and male Luer slip outlets. Polyethersulfone (PES) membranes provide the fastest flow rates, low protein binding and low extractables 100% integrity tested, sterile and certified nonpyrogenic and noncytotoxic Manufactured in accordance with ISO 9001 standards
Gentronix has launched a new, accurate and fast in vitro mammalian cell genotoxicity assay - GreenScreen HC. The TK6 host cells are p53 competent and familiar to most genetic toxicology laboratories. A patented GFP reporter system exploits the proper regulation of the GADD45a gene. The assay delivers both high specificity and high sensitivity and detects all common mechanistic classes of genotoxin. The 96-well microplate for…
E-WorkBook is driving the revolution in laboratory notebooks and experimental data. The ability to share, search and query experimental data in real time, control access and issue task requests to other team members, allows E-WorkBook™ to offer an organization the opportunity to drive the research process with improved efficiency and enhanced security. Life science organizations invest considerable time and money on protecti…
BioBook (E-WorkBook for biology) delivers complete late stage discovery and early preclinical research data management. Offering a compliant environment with superior flexibility, BioBook (E-WorkBook for biology) simplifies the capture, analysis and reporting of complex, multi-dimensional experimental data, with interactive complex statistics and graphing. BioBook is a robust and easy to use application that controls every st…
The latest version of SARview combines a flexible and intuitive user interface for unparalleled usability with IDBS’ new visualization technology – making SARview 6.1 one of the most powerful SAR reporting tools currently available. Incorporating IDBS’ SmartViz technology, SARview delivers multiple data views (in addition to table, tile and profile) within one application – which removes the necessity for third-party reporting…
XLfit® is a powerful curve-fitting and data analysis package that integrates completely with Microsoft® Excel. XLfit offers an extensive selection of data analysis and calculation tools, including a superior range of fit and statistics models as well as charts and graphs to visualize, interpret and present experimental data, all in Excel.XLfit works within the familiar Excel spreadsheet environment to enable curve fitting an…
With the all new CLC RNA Workbench, CLC bio brings you complex analysis of RNA molecules in a fully integrated, user-friendly and graphically advanced bioinformatics framework. Advanced The CLC RNA Workbench gives the user easy access to a range of complex algorithms and options. RNA secondary structures can be predicted using state-of-the-art free energy minimization algorithms and parameters, thermodynamic and statistical d…
The new Guava Nexin® reagent monitors induction of apoptosis quickly and easily, with minimal chance for contamination. Annexin V is a calcium-dependent phospholipid binding protein with high affinity for phosphatidylserine (PS), a membrane component normally localized to the internal face of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Ann…
Fluorescein-conjugated anticoagulant for the detection of phosphatidylserine in the outer leaflet of apoptotic cellsProduct Description Detection: Annexin-V-FLUOS can be directly detected in FACS analysis and immunochemistry without a secondary detection system. Sample material: Cell lines and freshly isolated cells. Specificity: Annexin-V binds in a calcium-dependent manner to negatively charged phospholipid surfaces, and sho…
Biotin-conjugated anticoagulant for the detection of phosphatidylserine in the outer leaflet of apoptotic cellsProduct Description Detection: Annexin-V-Biotin can be used in immunohistochemistry with a secondary detection system (e.g., Streptavidin-POD conjugate). Sample material: Cell lines and freshly isolated cells Specificity: Annexin-V binds in a calcium-dependent manner to negatively charged phospholipid surfaces, and…
Alexa 568-conjugated anticoagulant for the detection of phosphatidylserine on the outer leaflet of apoptotic cellsBenefits Detection flexibility: Analysis of results with flow cytometry and/or fluorescence microscopy. Alexa is a red dye, which can be used for double or triple staining with other fluorescent markers (e.g., fluorescein-labeled surface markers). Accuracy: Accurately distinguish apoptotic cells from necrotic…
Kit for the detection and quantification of apoptosis and differentiation from necrosis at the single-cell level, based on Annexin-V-labelingProduct Description Detection: Annexin-V-FLUOS can be directly detected in FACS analysis and immunochemistry without a secondary detection system. Sample material: Cell lines and freshly isolated cells. Specificity: Annexin-V-FLUOS binds in a Ca2+-dependent manner to negatively charged ph…
Kit for the detection and quantification of apoptotic cell death on a single-cell level by light microscopy in immunocyto- and immunohistochemistry Benefits Sensitive: The maximum intensity of labeling (cell staining) of apoptotic cells is higher than the nick translation method. Fast: The use of fluorescein-dUTP allows analysis of the samples directly after the TUNEL reaction, but before the addition of the secondary d…
Kit for the detection and quantification of apoptotic cell death on a single-cell level by flow cytometry and fluorescence microscopy, and for double labeling with fluorescein-labeled cell markers (TMR red)Benefits Convenient: No secondary detection system required. Accurate: Identification of apoptosis at a molecular level (DNA-strand breaks) and identification of cells at the very early stages of apoptosis. Flexible:…
