Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Precellys® 24 Touch

Bertin Technologies

Precellys ® 24 Touch is the ideal lab homogenizer to prepare any kind of biological sample, from the softest to the hardest. It can treat up to 24 samples at a time and has been validated on more than 1,500 different samples. The intuitive touchscreen interface of Precellys ® 24 Touch makes it really easy to use. Thanks to its exclusive vacuum-based tube locking system and its specific design, Precellys ® 24 Touch is compl…

4.8/5.0
|5 Reviews
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Transferpette® S

BRANDTECH® Scientific, Inc.

BRAND Transferpette® S pipettes offer superior performance, comfort, and value. Constructed with innovative composite materials, the Transferpette® S pipettes are lightweight and fully autoclavable.  The 4-digit display is easy to read for precise volume settings, and is always visible during pipetting. Adjustable and fixed-volume single channel pipettes from 0.1µL to 10mL, multichannels from 0.5µL to 100µL. Features:…

4.7/5.0
|11 Reviews

BRANDplates Immunology Microplates - immunoGrade, hydroGrade™ and lipoGrade™

BRANDTECH® Scientific, Inc.

NEW immunoGrade™, hydroGrade™, and lipoGrade™ BRANDplates® from BrandTech Scientific feature specially treated surfaces for use in a variety of immunological assays, such as ELISA, RIA, FIA and more. Available in a full range of well shapes and colors in 96-, 384-, and 1536-well formats. 96-well BRANDplates® immunoassay microplates feature blue alphanumeric embossing for easy well identification. immunoGrade™ — High Binding Ca…

4.7/5.0
|1 Review

Cyto-Mine®

Sphere Bio

Cyto-Mine® - The Single Cell Analysis and Monoclonality Assurance System. Cyto-Mine®  is a fully automated platform which integrates high-throughput and selective single cell screening, sorting, isolation and monoclonality assurance using high quality imaging.

4.9/5.0
|2 Reviews
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Cytek® Aurora

Cytek Biosciences

The Cytek® Aurora offers unprecedented assay flexibility and panel complexity thanks to our unique, full-spectrum optical design. With up to 5 lasers and 64 fluorescent detectors, the Cytek® Aurora can capture the entire emission spectrum from each fluorochrome. This makes it possible to now run 40 colors in one tube, a first for 40 fluorescence-based flow cytometry.

4.8/5.0
|14 Reviews
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FastDNA SPIN Kit for Soil™

MP Biomedicals

Isolate Pure DNA from Cells Present in Soil or Other Environmental Samples! Thorough lysis in seconds of any microorganism present in environmental samples. Ready-to-use DNA for quantitative and qualitative characterization of microbial soil communities. Excellent reproducibility for an optimum assay-to-assay consistency. Total removal of humic acids and PCR inhibitors for a successful investigation of microbial di…

4.6/5.0
|16 Reviews
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Pipette tips - ep Dualfilter T.I.P.S.

Eppendorf

There are certain situations in the lab in which suitable safety precautions must be taken in counteract any potential risks and to prevent any unpleasant surprises. It must be possible to anticipate in advance the dangers presented by carryover effects from radioactive, highly toxic or infectious sample material as well as the contamination risk caused by foreign DNA (e.g. as a result of aerosol formation).Our ep Dualfilter T…

5.0/5.0
|5 Reviews
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MixMate from Eppendorf - a compact and amazingly versatile benchtop mixer

Eppendorf

Compact and amazingly versatile, benchtop MixMate can be used for virtually any mixing application. It accommodates micro test tubes, PCR plates, deepwell plates and MTPs. It features an integrated vortex ing function and an operating concept that is as simple as it is intelligent. 2DMix-Control: uniquely fast and controlled mixing movement Current findings show that rpm speed is not the only determining factor in effici…

4.5/5.0
|4 Reviews

ThermoMixer®

Eppendorf

The new generation of Eppendorf ThermoMixer® and ThermoStat incubator raise sample preparation to the next level Ever since the launch of the company’s first performance-defining Mixer and the first Thermostat in 1964 Eppendorf has been at the forefront of mixing and temperature control technology for µL volumes. Thanks to Eppendorf’s continuous development, an exciting new generation of Temperature Control and Mixing Instrume…

4.5/5.0
|16 Reviews
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ETHOS X microwave extraction system for fat determination

Milestone

The process of fat determination in food and feed matrices is a routine analysis still relies on outdated and matrix-dependent methods which use obsolete and time-consuming technologies. The ETHOS X offers a new approach to gravimetric fat determination, moving toward a more modern, greener and more efficient approach to total fat, Fatty Acid Methyl Ester (FAME) and free fat determinations in food and feed matrices.

5.0/5.0
|1 Review
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ApoTox-Glo™ Triplex Assay

Promega Corp.

The ApoTox-Glo™ Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well. First, viability and cytotoxicity are determined by measuring two differential protease biomarkers simultaneously with the addition of a single nonlytic reagent containing two peptide substrates. The live-cell protease activity is restricted to intact viable cells and i…

4.6/5.0
|3 Reviews
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Griess Reagent System

Promega Corp.

The Griess Reagent System measures nitrite (NO2–), which is one of two primary stable and nonvolatile breakdown products of nitric oxide (NO). Nitric oxide is an important physiological messenger and effector molecule in many biological systems, including immunological, neuronal and cardiovascular tissues. This assay relies on a diazotization reaction that was originally described by Griess in 1879. Through the years, many mod…

4.7/5.0
|1 Review
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ROS-Glo™ H2O2 Assay

Promega Corp.

The ROS-Glo™ H2O2 Assay is a homogeneous, fast and sensitive bioluminescent assay that measures the level of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), directly in cell culture or in defined enzyme reactions.   This assay allows identification of conditions or test compounds, such as small molecule inhibitors or inducers, that alter ROS levels. The scalable multiwell format couples a stable luminescent si…

5.0/5.0
|2 Reviews
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CellTiter-Glo® Luminescent Cell Viability Assay

Promega Corp.

The CellTiter-Glo® Luminescent Cell Viability Assay(a,b) is a homogeneous method of determining the number of viable cells in culture based on quantitation of the ATP present, an indicator of metabolically active cells. The CellTiter-Glo® Assay is designed for use with multiwell formats, making it ideal for automated high-throughput screening (HTS), cell proliferation and cytotoxicity assays. The homogeneous assay procedure in…

4.7/5.0
|22 Reviews
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CellTiter-Glo® 2.0 Assay

Promega Corp.

The CellTiter-Glo® 2.0 Assay provides a homogeneous method for determining the number of viable cells in culture by measuring the amount of ATP present, which indicates the presence of metabolically active cells. The CellTiter-Glo® 2.0 Assay is based on the original CellTiter-Glo® Assay chemistry but with improved storage convenience for easy implementation. The CellTiter-Glo® 2.0 Assay is provided as a single, ready-to-use re…

4.9/5.0
|2 Reviews
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Lactate-Glo® Assay

Promega Corp.

The Lactate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of L-lactate in biological samples. Lactate is produced by glycolysis, a major metabolic pathway responsible for glucose homeostasis and energy production (1,2). Once considered merely a byproduct of glycolysis, lactate is now considered an important regulatory molecule of intermediate metabolism involved in cancer development, diabet…

5.0/5.0
|1 Review
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Digitonin

Promega Corp.

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

5.0/5.0
|1 Review
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CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS)

Promega Corp.

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

5.0/5.0
|2 Reviews
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