Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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IVARO Tube Handler AP

SARSTEDT AG

IVARO AP is more than just a liquid handler. It supports you in all types of sample preparation. Filling liquids into several identical tubes is just as easy as aliquoting samples into different containers and microtest plates, or creating dilution series.

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In vitro NASH Contract Research Services by CN Bio

CN Bio

CN Bio supports non-alcoholic steatohepatitis (NASH) therapeutic development via fast-track NASH Contract Research Services. NASH Services enable you to gain instant access to CN Bio’s expertise and one of the most advanced human in vitro models available. Submit lead candidates for screening and receive human translatable data for insightful preclinical candidate prioritization, clinical trial design and optimization.

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Drug Metabolism and Safety Toxicity Testing Services

CN Bio

CN Bio supports R&D efforts via fast-track Drug Metabolism and Safety Toxicity Testing Services that deliver human translatable insights from lead candidates in a few weeks and at lower cost than animal studies. By accessing the Company’s expertise and advanced in vitro liver-on-chip models, these Services enable researchers to step beyond standard in-house laboratory workflows for better informed pre-clinical decisions.

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Steripak™ Filter Units

Merck

Steripak-GP filter units are designed for larger scale pressure-driven filtration of tissue culture media with or without serum. They are single use and are not autoclavable. The filter units come in two sizes, with the smaller unit able to filter up to 10 L and the larger up to 20 L. Both sizes utilize the low protein binding, fast flow 0.22 µm EMD Millipore Express membrane.

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Steritop® Filter Units

Merck

Steritop bottle top filter units provide a large filter area for rapid sterile filtration of aqueous fluids into narrow-mouth (33 mm) or wide-mouth (45 mm) bottles. A small tab inside the funnel secures an optional prefilter in-place during filtration. For added protection against contamination, the threads for bottle attachment have been slightly recessed in case the funnel accidentally touches a work surface

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IRDye Click Chemistry Reagents

LICORbio

IRDye® Click Chemistry reagents (DBCO, Alkyne, and Azide) offer convenient, versatile and reliable methods for biomolecule labeling. With a variety of in vitro and in vivo applications, from biomarker isolation to assay development.

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Oxyntomodulin (OXM) ELISA

Ansh Labs

OXM causes weight loss via suppression of food intake and increase in energy expenditure. OXM administration was also reported to increase heart-rate in mice. Besides regulating glucose homeostasis in monogastric animals, OXM also increases the concentration of insulin and glucose in plasma of Holstein cattle under normal physiological conditions. It has been shown that Type 2 diabetes patients have lower levels of OXM and lev…

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Bioactive IGF-I ELISA

Ansh Labs

The Ansh Labs Bioactive IGF-I kit uses a highly sensitive two-site antibody method which allows detection of bioactive IGF-I. This assay enables accurate measurement and differentiation of bioactive IGF-I from total IGF-I levels. Assessment of bioactive to total IGF-I ratio will be informative and advance our understanding of IGF-I function and regulation in different physiological and disease states.

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IGFBP-4 (Total or Intact) ELISA

Ansh Labs

The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects.

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PAPP-A ELISA

Ansh Labs

During pregnancy, PAPP-A is produced in high concentrations by the trophoblast and released into maternal circulation. In addition to trophoblasts, PAPP-A expression has been reported in various tissues, including endometrium, testis, atherosclerotic arteries, kidney, bone, colon, and other adult and fetal tissue.

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Activin B ELISA

Ansh Labs

Activin B exhibits a wide range of biological activities, including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

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Glucagon ELISA

Ansh Labs

The Glucagon Enzyme Linked Immunosorbent Assay (ELISA) kit provides materials for the quantitative measurement of Glucagon in human plasma and other biological fluids.

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picoPAPP-A ELISA

Ansh Labs

The picoPAPP-A enzyme linked immunosorbent assay (ELISA) kit is useful in detection at low concentrations of Pregnancy Associated Plasma Protein A for studies of non-pregnant physiological states, pregnancy, dysfunctions of placental formation, certain cancers, and cardiovascular disease

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