Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Comet Assay IV - scoring system

Perceptive Instruments

Comet Assay IV's unique single-click scoring method and ultra-fast live video picture make it the most efficient and easy-to-use system available for measuring DNA damage using single cell gel electrophoresis. There are no complicated parameters to adjust and no hardware to install - simply connect the camera and start scoring. Working closely with leading experts in the field, Perceptive Instruments have released Comet Assa…

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Ames Study Manager

Perceptive Instruments

The AMES STUDY MANAGER is an integrated suite of software for conducting Ames tests according to regulatory guidelines. It has been designed to fulfil the requirements of safety assessment laboratories in pharmaceutical, medical device and chemical companies as well as Contract Research Organisations. The system is highly flexible, accomodating almost any experiment design and allowing sharing of controls between experimen…

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STP 420ES Rotational Tissue Processor

Thermo Fisher Scientific

As the leader in the innovation of stains, reagents, and instrumentation, the next generation of the tissue processor has been created– Thermo Scientific STP 420ES. This truly revolutionary instrument can accommodate overnight processing, same-day processing, or just about anything in between—with this dual chamber processor, the choice is really yours. Performance STP 420ES tissue processor features continuous movement o…

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Histostar

Thermo Fisher Scientific

Today's embedding centers can be uncomfortable, hot, or poorly illuminated, leading to fatigue and potential errors. The new Thermo Scientific HistoStar Embedding Workstation allows users to embed comfortably and efficiently. With brightly illuminated work surfaces, cool and contoured arm rests and high throughput capacity, this workstation delivers significant improvements in ergonomics and efficiency. Brightly illuminated…

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NanoFlow Metering System

Eksigent Technologies

Handle small volume samples with unprecedented precision at flow rates from 1 nL/min to 10 µL/min and backpressures to 3,000 psi Integrates easily into your workflow Simple interfaces make the NanoFlow Metering System an easy plug-in solution. standard low-volume capillary fittings for connection to detectors, chips, and standard liquid handing equipment, including autosamplers. Ideal for applications such as reagent met…

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SilicoCyte

CytoGenomics Inc

SilicoCyte™ is an advanced, modular, flexible and highly integrated microarray analysis platform designed for automated image analysis, comprehensive data annotation, elaborate data analysis and advanced data visualization.It has superior data management and data mining capabilities along with effective project management features that include organizing, assigning and monitoring projects at different levels.SilicoCyte™ suppor…

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SpeedVac Concentrator SPD131DDA

Thermo Fisher Scientific

The SPD131DDA enhanced performance SpeedVac concentrator is a simple to use, bench-top concentrator.  It is economical and is ideal for personal or low through-put evaporation of strong acids, bases and aggressive organic solvents, approved for combinatorial chemistry.  Digital programming enhances usability. Product Detail The SPD131DDA is designed to handle the rigors and solvents of combinatorial chemistry. It incorpo…

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Express SpeedVac Concentrator SC250

Thermo Fisher Scientific

High durability, heavy-duty design incorporates a ceramic bearing magnet assembly for maximum chemical resistance and reliability.  A high evaporation rate is achieved by extra-wide tubing and an extra large mouth glass condensation flask. Customize your concentrator configuration to your application. Product Detail The Express SC250 is a drug discovery modular SpeedVac concentrator designed for the rigors of industrial u…

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InsituPro VSi

Intavis Inc.

The InsituPro VSi is INTAVIS’ next generation instrument for automated in situ hybridization and immunohistochemistry – it represents the third generation of the InsituPro product line. The InsituPro VSi maintains the flexibility and versatility of the InsituPro VS but additionally features a number of functions often requested by our customers such as a buffer preheating for posthybridization washes and more flexibility in te…

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Quantikine® ELISA Kit for Measuring High Molecular Weight Adiponectin

Bio-Techne

R&D Systems now offers a Quantikine ELISA Kit for measuring high molecular weight (HMW) Adiponectin/Acrp30 in serum or plasma. This is the first commercially available ELISA designed to measure HMW Adiponectin without the need for proteolytic pretreatment of the sample. HMW Adiponectin is the primary bioactive form with insulin-sensitizing activity. Its circulating levels negatively correlate with obesity, insulin resistance,…

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Systat 13

Systat Software Inc

SYSTAT 13 is a versatile and comprehensive statistical software package. It employs a staggering range of powerful techniques to help conduct many types of research. Novice statistical users can use SYSTAT’s menu-driven interface to conduct simple analyses and produce beautiful 2D and 3D graphics for presentations or reports. Those in need of advanced analysis can use SYSTAT’s more sophisticated statistical routines, and creat…

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DILI Assay

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

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EPP (Endocrine Profiler Panel)

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…

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BluePippin Size Selection System

Sage Science

The BluePippin is a preparative electrophoresis platform for collection of size-selected DNA or protein samples. The system automates DNA or protein size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries, or upstream of p…

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Human Multipotent Mesenchymal Stromal Cell Multi-Color Flow Cytometry Kit

Bio-Techne

Product Description This kit contains four conjugated antibodies (and corresponding isotype controls) that can be used for single-step staining of human multipotent mesenchymal stromal cells (hMSCs) (1 - 4): Positive Markers • CD105-PerCP (Clone 166707; mouse IgG1) • CD146-CFS (Clone 128018; mouse IgG1) • CD90-APC (Clone Thy-1A1; mouse IgG2A) Negative Marker • CD45-PE (Clone 2D1; mouse IgG1) This kit also contains Staining Buf…

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VERSA 10 Workstation

Aurora Instruments Ltd

The VERSA 10 addresses the needs of research groups requiring high throughput liquid handling automation from a small bench top workstation. By combining an 8-channel manifold with a compact, 6 position deck, this workstation enables researchers to carry out large projects even when located in a fume hood or other similar areas with limited space. The VERSA 10 is the ideal solution for large research facilities, as multiple sy…

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Automated Pipetting - Neon 100 with Hood

Xiril AG

Enclosed – safe – sound: Xiril’s Neon100 with Hood Xiril liquid handling robots are ideally suited to perform a large number of liquid handling tasks in automation solutions. E.g. processes such as nucleic acid separation or PCR setup can easily be automated. The proven pipetting robot Neon is available with up to 36 positions on the worktable, carrying one or two robotic arms facilitating your daily pipetting routine. The bas…

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PathXL Simulator

PathXL

PathXL™ Simulator is a comprehensive diagnostic training package aimed at supporting early stage training for residents in pathology. We call this unique approach “learning by simulation” since trainees can work through real cases and assess how well they have performed. This approach to training has been completely embraced by numerous laboratories across the world including the Thames and Medway Training Schools, Liverpool t…

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6875 Freezer/Mill®

SPEX SamplePrep, LLC

The 6875 Freezer/Mill® is a large cryogenic mill that accommodates sample sizes ranging from 0.1 - 100 grams. Specifically designed for cryogenic grinding and pulverizing tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. The new high resolution display is user-friendly and shows the each stage of the grinding process. It also shows the Run history, Training videos and manuals and a…

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Shatterbox®

SPEX SamplePrep, LLC

The Shatterbox® is a heavy duty, Swing Mill that is designed for pulverizing dry, brittle samples and slurry grinding. It features a sound-proof enclosure and a timer display that counts down the minutes and seconds remaining in the process. It accommodates sample sizes ranging from 2 - 100 grams and is capable of grinding Cement, Soils, Ceramics, Slag, Rocks, Minerals, Ores, Pharmaceuticals, Sulfur Pellets, Dried Plant Ma…

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6875D Freezer/Mill®

SPEX SamplePrep, LLC

The 6875D Freezer/Mill® is a high-throughput, dual chamber cryogenic grinder with a self-contained liquid nitrogen tub and insulated case. Specifically designed for cryogenic grinding and pulverizing of tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. This mill chills samples in liquid nitrogen then pulverizes them with a magnetically driven impactor. The new high resolution displa…

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8000D Mixer/Mill®

SPEX SamplePrep, LLC

The 8000D Mixer/Mill® is a dual clamp, high-energy ball mill that grinds dry, brittle samples such as Rocks, Minerals, Sand, Cement and Slag. It can also be utilized for mechanical alloying, slurry grinding, blending powders and mixing emulsions. It accommodates sample sizes ranging from 0.2 - 10 grams per vial and has a figure eight motion that has been proven to be more efficient than side-to-side or planetary motion fou…

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