Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Beacon® Optofluidic System

Bruker Cellular Analysis

With the Beacon system’s light-speed workflows, you’ll gain insights, iterate and innovate. Replace a roomful of equipment with the Beacon system Work fast with individual cells  Perform assays at any time, as often as you need Track phenotype and genotype of single cells or clones Automate and scale workflows beyond manual, time-intensive analysis Generate great insights through deep profiling of each cell or clone

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iLite® Functional Bioassays

Svar Life Science AB

The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.

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iLite® Fc Effector Activity Bioassays

Svar Life Science AB

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

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Anti-CCP Assay

Svar Life Science AB

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

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CRO Services

Svar Life Science AB

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

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Biomarker Discovery Services

Svar Life Science AB

Expert Biomarker Discovery Services using cutting-edge technologies such as high-quality proteomics with Proximity Extension Assay (PEA) technology from Olink, and ultra-sensitive detection with proven Simoa technology. We offer ideal broad screening-to-targeted biomarker discovery solutions in different therapeutic areas.

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Bioanalytical Services

Svar Life Science AB

A specialized and GxP-certified laboratory for Bioanalytical Service Solutions -with scientific expertise & advanced technologies. We offer assay development, validation, and sample analysis of pharmacokinetics, toxicokinetic, pharmacodynamics, immunogenicity, and biomarker analysis.

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Glass Block Manifold

UCT, Inc.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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traceCLEAN Acid steam cleaning system

Milestone

Cleaning various items used in ultra-trace analysis work is a critically important laboratory routine. traceCLEAN assures best cleaning quality of your TFM, glass and quartz parts for ICP/ICP-MS accessories. Any trace metal contaminants stay within the reservoir and do not come in contact with the cleaned trace accessories. The cleaning process with the traceCLEAN takes about an hour, enhancing the overall lab workflow. 

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ETHOS X for terpene extraction in cannabis labs

Milestone

ETHOS™ X microwave extraction line allows quick heating of the cannabis material for terpene isolation. Solvent-free extraction process takes only a few minutes and prevents any thermal degradation often noticed during use of conventional extraction methods. The fresh and characteristic taste of strain-specific cannabis is maintained, and high-quality terpenes are assured. The ETHOS X 2.0 is our latest generation of benchtop…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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HaloTag® Mammalian Protein Purification System

Promega Corp.

It can be challenging to purify sufficient high-quality protein from mammalian cells. Boost protein recovery 30-60% with an optimized covalent protein tag, called HaloTag®. This complete kit offers strong improvements in recovery, purity, cost and protein functionality over historical FLAG® and poly-His tag purification strategies.

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ONE-Glo + Tox Luciferase Reporter and Cell Viability Assay

Promega Corp.

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to make these measurements in a single well of a plate, negating the need to run parallel assays. The first part of the assay is a nonlytic fluorescence assay (CellTiter-Fluor™ Cell Viability Assay) that measure…

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Magne™ Protein A and Magne™ Protein G Beads

Promega Corp.

Magne™ Protein G and Magne™ Protein A Beads are magnetic affinity beads with high specificity and high capacity for purification of immunoglobulins from cell culture media, ascites and serum samples.   These paramagnetic beads are composed of iron encapsulated in macroporous cellulose with low nonspecific binding. The magnetic beads use a novel attachment chemistry to immobilize recombinant Protein G or Protein A protein…

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MethylEdge™ Bisulfite Conversion System

Promega Corp.

The MethylEdge™ System provides an efficient method to rapidly perform bisulfite conversion with minimal DNA fragmentation, giving you more intact, converted DNA for downstream applications.   Start with as little as 100pg of input DNA for those precious, limited samples. Use the MethylEdge™ System with other DNA Methylation Workflow reagents to perform sensitive DNA methylation analysis on many sample types. The rapi…

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