Drug discovery > Target Discovery Products & Reviews

Beads containing sufficient covalently-linked Protein A for a binding capacity of 20+/-2 milligrams human IgG per 1 milliliter.

This unique formulation of cell culture freezing media is for cryopreservation of a broad spectrum of mammalian cells (see viability data). The reagents used in these products are certified to be virus and mycoplasma free. Contains 10% DMSO, calf & fetal bovine serum

This unique formulation of cell culture freezing media is for cryopreservation of a broad spectrum of mammalian cells (see viability data). The reagents used in these products are certified to be virus and mycoplasma free. Contains 10% DMSO, calf & fetal bovine serum

GLP-1 is secreted from gut endocrine cells in response to nutrient ingestion and plays multiple roles in metabolic homeostasis.

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Sterivex filter units work with syringes, peristaltic pumps or pressure vessels. They eliminate the risk of contamination associated with decanting or pipetting.Sterivex units are designed to dispense into virtually any storage container. The devices are available with different outlet connectionsSterivex filter units can process volumes up to 1,000 mL or 2,000 mL, depending on the type of membrane used in the device. A choice…

The Steriflip filter unit is designed to work with standard 50 mL centrifuge tubes, which eliminates sample transfer. To filter, just attach the unit to a 50 mL centrifuge tube containing your sample, flip it over, and apply the vacuum. When finished, the filtrate collects in the attached 50 mL centrifuge tube.Steriflip Nylon Net filters are now available in 40, 60 and 100 µm pore sizes, making them ideal for stem cell, cardio…

The Stericap ™ PLUS Universal Bottle-Top Filter Device provides fast, large-volume filtration into any sized bottle.

With their vertical membrane design, Amicon Ultra 0.5 mL filters deliver great performance and lower spin timesConcentrates 500 µL down to 15 µLConcentration factor 25 x to 30 xHigh sample recovery (greater than 90% of dilute starting solution)Fast processing time - 10 to 30 minutesConsistent recoveries thanks to the reverse spin capabilityReverse spin capability provides consistent recoveries

4 mm syringe filter with a Hydrophilic PVDF membrane, for non-sterile filtration, has a 0.22 µm pore size used in fine particle removal from aqueous & mild organic solutions.

The MILLIPLEX® MAP Mouse Cytokine/Chemokine Magnetic Bead Panel II - Premixed 12 Plex, MCP2MG-73K-PX12is used for the simultaneous quantification of the following Mouse analytes: Epo, Exodus-2, Fractalkine, IL-16, IL-21, IL-22, IL-25, IL-28B, MCP-5, MIP-3α, MIP-3β, TARC

The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel - Premixed 14 Plex is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-18, GM-CSF, GRO/KC, IFN-γ, MCP-1, TNF-α

Thermo Scientific Nunclon Vita is a unique energy-treated polystyrene surface that enables growth of most cell lines directly on the surface without using matrix coatings or feeder cells. Thermo Scientific Nunclon Vita is the latest addition to an exceptional portfolio of cell culture surface products, including the Thermo Scientific Nunclon Delta surface, and joins an extensive range of technologies and products for all basic…

PC or Mac, includes incubator, Microplate Manager 6 software (#168-9520), USB2 cable

4 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

The DPPIV-Glo™ Protease Assay is a homogeneous, luminescent assay that measures dipeptidyl peptidase IV (DPPIV) activity. DPPIV is a serine protease that cleaves N-terminal dipeptides from polypeptides with L-proline or L-alanine at the penultimate position. The DPPIV-Glo™ Assay provides a proluminescent DPPIV substrate, Gly-Pro-aminoluciferin, in a buffer system optimized for DPPIV and luciferase activities. The addition of a…

Assay Analysis and Management

The ONE-Glo™ Luciferase Assay System provides a highly sensitive, robust, homogeneous assay for detection of firefly luciferase reporter gene expression in mammalian cells. Ideally suited for high- and ultrahigh-throughput applications, the ONE-Glo™ Assay contains a new luciferase substrate, resulting in a reagent that is more stable, more tolerant to sample components, and has less odor than standard luciferase assay reagents…

jetPRIME™ is a new versatile and powerful DNA and siRNA transfection reagent for day-to-day experiments. jetPRIME™ ensures high DNA transfection efficiency and excellent gene silencing in a variety of adherent cells and is ideal for DNA/siRNA co-transfection. jetPRIME™ is very gentle to cells since it requires low amounts of reagent and nucleic acid during transfection. Effective and nontoxic DNA and siRNA delivery is essentia…

Roche NimbleGen provides the most sensitive and specific DNA Methylation microarrays and services on the market. Methylated DNA regions are accurately mapped using a combination of affinity-based enrichment, such as Methylated DNA Immunoprecipitation (MeDIP) or the Methylated CpG Island Recovery Assay (MIRA), followed by microarray analysis. Roche NimbleGen offers several types of DNA Methylation arrays for a variety of organi…

Use the Millicell® EZ SLIDE to culture, fix, stain and view your cells all in one device. There’s no need to tediously move cover slips from your culture dish to a slide. Leave the wells intact to fix and stain and acquire data simply and quickly with Millicell EZ SLIDES. Features of the the Millicell® EZ SLIDE:  •  Breakable tabs for easy well removal   •  No tools required to remove wells from slide   •  No adhesive used to…

The ApoTox-Glo™ Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well. First, viability and cytotoxicity are determined by measuring two differential protease biomarkers simultaneously with the addition of a single nonlytic reagent containing two peptide substrates. The live-cell protease activity is restricted to intact viable cells and i…

The TPP tissue culture flasks stand for high quality aspects. Advantages of the tissue culture flask: uniform even surface of the growth area crystal clear transparency stable, slip-free stacking of several flasks bilateral marking area accurate volume scale for optic control of the filling volume For optimum tissue growth, the growth area is opto-mechanical treated. This enhances cell adhesion and cell growth. T…

shRNAmir-GFP: Visualize RNAi Thermo Scientific GIPZ Lentiviral shRNAmir advantages: shRNAmir design for specificity and increased knockdown efficiency TurboGFP marks cells expressing shRNAmir Efficient low copy knockdown- Important for pooled screens Genome-wide human and mouse coverage Perform efficient RNAi in primary and non-dividing cells Guaranteed* knockdown Please note that the pGIPZ and pTRIPZ vectors a…

Kit Summary: • Detection method- Absorbance (450 nm) • Sample type- Cell and Tissue culture supernatants, urine, plasma and serum, as well as many other biological fluids etc. • Species reactivity- Mammalian • Application- The G6PDH Assay Kit can detect as low as 0.04mU G6PDH per well. Features & Benefits: • Simple procedure; takes ~ 30-60 minutes • Fast and convenient Kit components: • G6PDH Assay Buffer • G6PDH Substrate • G…