Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Venom Discovery Array (VDA)

Venomtech Limited

The Venom Discovery Array (VDA) is a naturally compressed, hit-to-tool screening library based on a 96-well automation compatible array. These VDA's can be customised to meet target specific needs, such as the 48 phylogenetically diverse tarantula species to target ion channels or snakes for cancer research amonst others.For further information please click on the company website link.

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SpeedVac Concentrator SPD131DDA

Thermo Fisher Scientific

The SPD131DDA enhanced performance SpeedVac concentrator is a simple to use, bench-top concentrator.  It is economical and is ideal for personal or low through-put evaporation of strong acids, bases and aggressive organic solvents, approved for combinatorial chemistry.  Digital programming enhances usability. Product Detail The SPD131DDA is designed to handle the rigors and solvents of combinatorial chemistry. It incorpo…

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Express SpeedVac Concentrator SC250

Thermo Fisher Scientific

High durability, heavy-duty design incorporates a ceramic bearing magnet assembly for maximum chemical resistance and reliability.  A high evaporation rate is achieved by extra-wide tubing and an extra large mouth glass condensation flask. Customize your concentrator configuration to your application. Product Detail The Express SC250 is a drug discovery modular SpeedVac concentrator designed for the rigors of industrial u…

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LightSwitch Single Gene GoClone Reporters

SwitchGear Genomics

The LightSwitch promoter reporter GoClone collection includes transfection-ready luciferase reporter constructs utilizing the novel RenSP luciferase technology for over 17,000 human promoters and highly optimized LightSwitch reagents. Measure the functional response of promoters to stimulus in nearly any cell-based system. Plus, advances in gene assay reagent and transfection technology eliminates the need for co-transfection…

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MultiPep RS

Intavis Inc.

The MultiPep RS is an automated multiple peptide synthesizer based on a pipetting robot operated by a dedicated PC software. Synthesis is being performed in 96 well filter plates, in disposable columns or on membranes (SPOT method).

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InsituPro VSi

Intavis Inc.

The InsituPro VSi is INTAVIS’ next generation instrument for automated in situ hybridization and immunohistochemistry – it represents the third generation of the InsituPro product line. The InsituPro VSi maintains the flexibility and versatility of the InsituPro VS but additionally features a number of functions often requested by our customers such as a buffer preheating for posthybridization washes and more flexibility in te…

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ResPep SL

Intavis Inc.

The ResPep SL is a fully automated tabletop peptide synthesizer. The chemistry is optimized for Fmoc-based peptide synthesis with standard activation by PyBOP, HBTU, DIC/HOBt or a similar protocol. Additional modules for large scales, micro scale and SPOT synthesis are available.

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DigestPro MSi

Intavis Inc.

Enzymatic digestion of proteins in polyacrylamide gel slices and subsequent analysis of the peptides by mass spectrometry has become a routine procedure in protein analysis. In solution digestion protocols for bottom-up proteomics complement it. The DigestPro MSi automates all those procedures to achieve high throughput under controlled and reproducible conditions.

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Immunoassay Microtiter Microplates

Thermo Fisher Scientific

Advanced features and careful design ensure the reliability of Microtiter microplates. In your immunoassays coating and washing are always even, and the recessed bottom keeps the surface clean and scratch free ensuring high optical performance. The microplates are available with different binding characteristics and formats.Product detail:Thermo Microtiter products have binding characteristics that include ImmulonTM hydrophobi…

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Luminescence Microtiter Microplates

Thermo Fisher Scientific

White Microtiter microplates are designed for use with light emitting markers. Pigments have been carefully selected to optimize assay performance. The white pigment eliminates cross talk while optimum reflection enables best performance in luminometric applications with low signals. These microplates are available in different formats and binding characteristics. Product detail: Thermo offers a selection of Microtiter micro…

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Fluorescence Microtiter Microplates

Thermo Fisher Scientific

Thermo black and white microplates help you to optimize your assay performance in fluorescent applications. These microplates are designed for use with light emitting markers, having carefully selected pigments to eliminate cross talk and reduce background signals of your assays. Different binding characteristics and formats are available. Product detail:Microtiter Microfluor microplates and universal/enhanced binding plates…

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Clear Bottom Microtiter Microplates

Thermo Fisher Scientific

These clear bottom microplates are sterile and thus ready to cultivate bacteria and fungi. TC treatment makes them perfect for mammalian tissue culture with no need for chemical treatments. They are individually packaged with lid and their unique design helps to eliminate cross-talk. The microplates are perfect for microscopic viewing and also suitable for top and bottom reading instruments. Low background fluorescence and lum…

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UV Microtiter Microplates

Thermo Fisher Scientific

Thermo UV microplates are designed specially for your applications adapted for the UV wavelength area. The performance is optimal down to at least 220 nm with fairly low absorbance background. Thus nucleic acid and protein determinations using this microplate made of UV light transmitting material are enabled at 260/280 nm. The microplate is also compatible with any standard microplate reading or liquid handling device. Produ…

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Coated Microtiter Microplates

Thermo Fisher Scientific

Streptavidin coated wells of the BioBind microplate offer biotin mediated binding for small or hydrophilic molecules. This surface is ideal for e.g. peptides, oligonucleotides and DNA hybridization assays. The streptavidin-biotin bond is extremely strong and stable, and utilizing this system problems associated with steric hindrance during the binding procedure can be avoided. Product detail: BioBind - Streptavidin Coated…

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SeqSolve Integromics

Integromics

SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data. By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is the only software able to provide scientists with such a combination of both cutting edge and intuitive user experience. Its Click And Go® technology enables the automatic processing of the data, whi…

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Corning® 5 mL Internal Threaded Polypropylene Cryogenic Vial, Self-Standing with Round Bottom

Corning Life Sciences

5 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

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Arrayed BAC library

Bio S&T

An arrayed or non-arrayed BAC library is the preferred choice for downstream applications such as hybridization screening; full-genome sequencing; BAC end sequencing or physical mapping projects. Amount of clones received is based on a guaranteed coverage and 120Kb average insert size. HMW DNA isolation and QC by HMW DNA enzymatic digestion are included. Deliverables for ARRAYED BAC library: Clones will be arrayed and amplifie…

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Screened BAC library

Bio S&T

A pooled BAC library is an invaluable tool for PCR-screening. It allows for the easy retrieval of BAC clones of interest. This type of library is especially useful when genome size is large and creating an arrayed library is cost-prohibitive. We typically construct a minimum 5X BAC library and BAC clones are then pooled and distributed in 96-well plates. Each well will contain about 400-500 original BAC clones. HMW DNA isolati…

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Normalized cDNA libraries

Bio S&T

Our cDNA libraries feature full-length-enriched and high quality size-fractionated cDNA. cDNA library construction is usually done in slightly-modified versions of pBluescript or pcDNA3.1. Insert sizes will range from about 0.5Kb to 4Kb. Concerning QC steps, we evaluate the average insert size, empty clone rate and clone concentration/tube before shipping out. We always provide a gel picture of randomly selected clones showing…

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APAgene™ GOLD Walking Kits

Bio S&T

APAgene™ GOLD Genome Walking Kits are designed to rapidly and reliably amplify unknown genomic DNA using our patented APA technology: 1. Isolate unknown genomic sequences flanking transgenes (including T-DNAs, gene traps, transposons), sequence-tagged sites (STSs) or expressed sequence tags (ESTs). 2. Isolate localized sequences flanking known sequences from large clones and genomic DNAs. 3. Sequence insert ends of large clone…

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ASH cDNA Subtracted Library

Bio S&T

ASH is APA-based, full-length-enriched, single-stranded cDNA subtraction hybridization library. - ASH cDNA subtraction is full-length-enriched and independent of PCR suppression. - ASH cloning is directional and does not involve normalization. - ASH method provides non-exponential amplification before subtraction because double-stranded cDNA is not required. - ASH method has a better subtraction effect because 1) a high ratio…

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x-tremeGENE DNA Transfection Reagents

Improve your cell analysis and use our powerful new transfection reagents: Efficiently transfect a broad spectrum of cells, including difficult-to-transfect cell lines and tumor cell lines. Generate physiologically relevant results using low cytotoxic reagents. Avoid time-consuming optimization using fast, reliable protocols.

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