Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Automated Pipetting - Neon 100 with Hood

Xiril AG

Enclosed – safe – sound: Xiril’s Neon100 with Hood Xiril liquid handling robots are ideally suited to perform a large number of liquid handling tasks in automation solutions. E.g. processes such as nucleic acid separation or PCR setup can easily be automated. The proven pipetting robot Neon is available with up to 36 positions on the worktable, carrying one or two robotic arms facilitating your daily pipetting routine. The bas…

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OneSource Instrument Services

PerkinElmer

Consolidating your laboratory services with one provider makes excellent business sense. You get one service contract instead of 20 or more for your instruments. You can locate any piece of equipment instantaneously and track every critical event, such as an instrument’s next scheduled service. Efficiencies of scale help you control lab costs and optimize lab operations. OneSource, our consolidated instrument service, is unpar…

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Finnigan™ vMALDI™

Thermo Fisher Scientific

The Finnigan vMALDI Ion Source system provides fast, automated MS and Data Dependent MS/MS analysis of digested protein mixtures in a single, rapid experiment. While LC/MS analysis times are typically 30 to 60 minutes, using the Finnigan LTQ with the vMALDI ion source generally requires less than a minute per sample enabling high throughput protein identification. Production: The Finnigan vMALDI Ion Source Thermo's new F…

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PathXL TMA

PathXL

Biomarker Discovery with Tissue Microarrays Using PathXL™ TMA, TMA experiments can be performed anytime, anywhere, reducing administrative costs and time. PathXL™ TMA is perfectly designed to support TMA scoring workflow and already used by pathologists worldwide, the system allows configuration of experiments in minutes. Access and view clinical metadata, the TMA core, scoring criteria and the TMA map all on a single interfac…

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IDS-iSYS Specialty Imunoassay System

Immunodiagnostics Systems Ltd (IDS)

The IDS-iSYS combines 50 years of instrumentation engineering experience with world-respected assay development skills into a compact, benchtop system that fully automates testing of the most challenging calcium, bone, growth and hypertension markers. Uncompromised Efficiency • Full, walk-away automation • Compact, benchtop design • Continuous loading with Batch, Random, and STAT flexibility • Easy operation with auto start-up…

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AutoMATE II

Rigaku Corporation

Highly accurate micro area residual stress with both iso- and side-inclination methods. In the past, if you wanted to make highly accurate residual stress measurements, you had to use an R&D diffractometer because of the accuracy of the goniometer. However this restricts the weight and size of the samples you can measure. On the other hand, dedicated laboratory and factory-floor residual stress analyzers suffer from reduced a…

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MicroMax-003

Rigaku Corporation

The MicroMax-003 is a third generation microfocus sealed tube X-ray generator for X-ray diffraction and crystallography. It is the perfect X-ray source for someone who wants the benefits of a microfocus X-ray source (low power consumption and long tube life) without the added maintenance that goes along with a more powerful rotating anode microfocus X-ray source.It consists of a tightly coupled microfocus generator and specia…

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AlumaSeal II™ Sealing Film for PCR and Cold Storage

J.G. Finneran Associates, Inc

A 38µm soft non-permeable aluminum foil sealing film with strong medical grade adhesive, AlumaSeal II™ sealing films eliminate the need for heat-sealing devices or mats during thermal cycling. Compared to other aluminum foils, AlumaSeal II™ has less tendency to roll back on itself when removing the backing paper and conforms well to the plate during applications. •   Easily pierceable with single or multi-channel pipettors and…

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6875 Freezer/Mill®

SPEX SamplePrep, LLC

The 6875 Freezer/Mill® is a large cryogenic mill that accommodates sample sizes ranging from 0.1 - 100 grams. Specifically designed for cryogenic grinding and pulverizing tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. The new high resolution display is user-friendly and shows the each stage of the grinding process. It also shows the Run history, Training videos and manuals and a…

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Shatterbox®

SPEX SamplePrep, LLC

The Shatterbox® is a heavy duty, Swing Mill that is designed for pulverizing dry, brittle samples and slurry grinding. It features a sound-proof enclosure and a timer display that counts down the minutes and seconds remaining in the process. It accommodates sample sizes ranging from 2 - 100 grams and is capable of grinding Cement, Soils, Ceramics, Slag, Rocks, Minerals, Ores, Pharmaceuticals, Sulfur Pellets, Dried Plant Ma…

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6875D Freezer/Mill®

SPEX SamplePrep, LLC

The 6875D Freezer/Mill® is a high-throughput, dual chamber cryogenic grinder with a self-contained liquid nitrogen tub and insulated case. Specifically designed for cryogenic grinding and pulverizing of tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. This mill chills samples in liquid nitrogen then pulverizes them with a magnetically driven impactor. The new high resolution displa…

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8000D Mixer/Mill®

SPEX SamplePrep, LLC

The 8000D Mixer/Mill® is a dual clamp, high-energy ball mill that grinds dry, brittle samples such as Rocks, Minerals, Sand, Cement and Slag. It can also be utilized for mechanical alloying, slurry grinding, blending powders and mixing emulsions. It accommodates sample sizes ranging from 0.2 - 10 grams per vial and has a figure eight motion that has been proven to be more efficient than side-to-side or planetary motion fou…

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LH96 Automated Homogenizer Workstation

OMNI International Inc.

The LH96 can be configured to combine multiple sample prep steps into one versatile, efficient and automated device. Quite literally, what used to take hours or days can now be completed in a matter of minutes, and without attendance. The LH96 integrates a core homogenizing platform, capable of efficiently processing a wide variety of samples from 5mL to 50mL tubes, with fully customizable liquid handling capabilities. Patent…

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VersaMAP™ Development System

Bio-Techne

The VersaMAP Development System offers our widest selection of potential analytes for Luminex-based multiplexing. The diluent supplied is suitable for most cell culture supernate samples. Samples with complex matrices, such as serum and plasma, may need further optimization. For multiplex kits validated by R&D Systems for use in complex matrices, please see our Fluorokine® MAP products. VersaMAP Development System product data…

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Fluorokine® Multianalyte Profiling (MAP) Kits

Bio-Techne

Fluorokine MAP Kits for the Luminex platform are highly efficient multiplex assays that have been validated for the quantification of factors in complex matrices and require little or no optimization. For a wider selection of analytes, please see our VersaMAP™ line of development kits validated for use with cell culture supernatants. Features Simultaneously detect multiple analytes Requires small sample volume (Undergoes simil…

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VersaMAP™ Magnetic Custom Multiplex Kits

Bio-Techne

The VersaMAP™ Magnetic Custom Multiplex Kits are our most efficient Luminex-based multiplex assays. These homogeneous, no wash assays utilize analyte-specific antibodies conjugated to superparamagnetic microparticles to simultaneously detect up to 25 user-defined phosphorylated receptor tyrosine kinases (RTKs) in a single sample. Available Kits VersaMAP Magnetic Human RTK Kit A VersaMAP Magnetic Human RTK Kit B Features • Comp…

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PGN003 PureGenome™ Next Generation Sequencing Library Amplifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN002 PureGenome™ Next Generation Sequencing Library A-Tail Enhancer

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN001 PureGenome™ Next Generation Sequencing Library DNA Modifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN004 PureGenome™ Next Generation Sequencing Library Validator Kit

Merck

The quality of sequence obtained from Next Generation sequencing platforms such as Illumina, Inc. requires the accurate determination of input library DNA. Loading too much DNA can lead to overlapping clusters and loss of read counts whereas too little input can lead to poor read lengths and lower sequence output. The PureGenome™ NGS Library Validator Kit measures the absolute amount of adapter-ligated, sequence ready DNA in I…

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NovaSeptum Sampling System

Merck

A sterile, closed, disposable system for sampling fluids from sterile and aseptic processes The unique NovaSeptum sampling system is ideal for general fluid and cell culture sampling from aseptic and sterile processes. Both systems can be configured for high purity or autoclavable sampling applications and as single or multiple sampling units. A wide range of holders and connectors are also available. •  Closed sampling elimin…

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OneTRAC™ combined service

Plexpress

OneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling f…

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Vena8 Fluoro+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Fluoro+™ biochip is ideal for studying cell receptor-ligand interaction and is compatible with confocal microscopy. As cells flow through the microcapillary of the Vena8 Fluoro+™ biochip, the cell surface receptors may interact with adhesion molecules or ligands which coat the microcapillary walls. Ideal for use with fluorescence immunostaining, confocal microscopy and for applications such as thrombosis.

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Vena8 Endothelial+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging an…

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