Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
A sterile, closed, disposable system for sampling fluids from sterile and aseptic processes The unique NovaSeptum sampling system is ideal for general fluid and cell culture sampling from aseptic and sterile processes. Both systems can be configured for high purity or autoclavable sampling applications and as single or multiple sampling units. A wide range of holders and connectors are also available. • Closed sampling elimin…
OneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling f…
The Vena8 Fluoro+™ biochip is ideal for studying cell receptor-ligand interaction and is compatible with confocal microscopy. As cells flow through the microcapillary of the Vena8 Fluoro+™ biochip, the cell surface receptors may interact with adhesion molecules or ligands which coat the microcapillary walls. Ideal for use with fluorescence immunostaining, confocal microscopy and for applications such as thrombosis.
The Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging an…
This is the suggested replacement for P-1ML-SQ-C. Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total volume is 1 mL
Prior to scanning a micro array slide, it is necessary to remove all wash buffer. This drying step is critical to obtain the best possible scanning results. The Slide Spinner dries 2 micro array slides within a 10 seconds - simply insert your slides into the cassettes and close the lid! The Slide Spinner quickly accelerates to 4800 RPM, the optimal speed for quick drying without any splashing. Open the lid and the rotor comes…
Lids are made of rigid polystyreneLids have a corner notch on the A1 corner to correspond to the corner notches found on all Corning® microplatesSterilized by gamma radiation
Safer alternative to formalin-based fixatives, contains no formaldehyde, mercury or gluteraldehyde, tissue retains a more natural look and feel enabling easier, smoother cutting and sectioning, no cross linking of tissues as experienced with formalin-based fixatives.
The K Series Cryogenic Systems provide reliable liquid nitrogen storage with controllable temperatures between -100ºC and -196ºC. The added safety of automatic filling, alarms, easy access to stored product, and the unique Temperature Gradient Suppression System significantly improves vapor phase storage temperature and recovery. K Series Cryogenic Systems Features: Temperature control standard Temperature monitor stan…
Revolutionary 2DGE Software Analysis of single 2D gels - Dymension 1 is ideal for users looking for software to analyse spots between samples containing one 2D gel only. It offers a range of automatic image correction features and methods for resolving and analysing spots on single gels. The software can be easily upgraded to Dymension 2 or 3 if the proteomics needs of the laboratory change.
(This is the suggested replacement for 355129) Made from optically clear polycarbonate Ideal for shaker culture applications Flat cap used for a closed liquid tight seal. Easy grip cap is designed to be more ergonomic. Sterilized by gamma radiation and certified nonpyrogenic RNase- and DNase-free
SOD or SOD-like activity detection. WST-1 based SOD inhibition assay, colourimetric microplate measurement, measures 100% inhibition by SOD, pH-independent IC50 determination, low background noise measurement.
Abasic site quantification in genomic DNA. Determine the number of abasic sites in genomic DNA samples, colourimetric microplate assay, detection range: 1-40 abasic sites per 1x10^5 base pairs DNA.
Ready-to-use dialysis device with a broad built-in range of precise MWCO's and all the needed accessory components built in for ultimate convenience. Features leak proof and re-sealable snap-on cap for sampling, colour coded dot for MWCO, broad floatation disk for buoyancy, 6 volume-specific size, 2 membrane types- biotech grade regenerated cellulose (RC) and biotech grade cellulose ester (CE).
Cellstain-Double Staining Kit is utilised for simultaneous fluorescence staining of viable and dead cells. Flurometric microscope detection, simultaneous determination of viable and dead cells.
GeneJuice® Transfection Reagent is a proprietary formulation optimized for maximal transfection efficiency, ease of use, and minimal cytotoxicity. This transfection reagent is a superior alternative to a wide variety of other techniques including calcium phosphate coprecipitation, electroporation, microinjection, biolistic particle delivery, and complex formation with DEAE-dextran. Whereas many available transfection reagents…
BugBuster® Master Mix combines BugBuster Protein Extraction Reagent with Benzonase® Nuclease and rLysozyme™ Solution in one convenient reagent. BugBuster Master Mix allows for maximum recovery of active soluble protein from both Gram-negative and Gram-positive bacteria. With the Master Mix, there is no need for dilution or separate addition steps. The two available package sizes provide sufficient reagents for protein extracti…
AVOID FREEZE/THAW CYCLES. The ProteoExtract Subcellular Proteome Extraction Kit is a tool for the differential extraction of proteins from adherent or suspension tissue culture cells according to their subcellular localization. The sequential extraction steps yield fractions containing cytosolic proteins, plasma membrane and organelle proteins, soluble nuclear proteins, and finally cytoskeletal and nuclear matrix proteins. To…
PhosphoSafe™ Extraction Buffer extracts cytosolic proteins from mammalian and insect cells while preserving their phosphorylation state. The reagent, an enhancement of the CytoBuster™ Protein Extraction reagent, includes four phosphatase inhibitors. PhosphoSafe is compatible with Western blotting, immunoprecipitations, and kinase assays.
Pellet Paint® NF Co-Precipitant* is a non-fluorescent dye-labeled carrier compatible with fluorescent sequencing. It facilitates rapid removal of BigDye™ Terminators (PE Corp.) during the alcohol precipitation of cycle sequencing reaction products. Cycle sequencing reactions can be precipitated rapidly with centrifugation times of 10 minutes. The easily visualized carrier provides a simple confirmation that precipitation has o…
Overnight Express™ Instant TB Medium is a complete granulated culture medium for high-level protein production without the need to monitor cell growth in the pET and other IPTG-inducible bacterial expression systems. Cell mass and target protein yield are often increased several-fold as compared with induction using IPTG. The method is based on media components that are metabolized differentially to promote growth to high dens…
White solid. Aminoglycoside related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3¡ä-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Intro…
Light brown lyophilized solid. Working concentration 50 mg/ml - 1 mg/ml for mammalian cell selection. Unique aminoglycoside antibiotic that inhibits the growth of prokaryotic (bacteria) and eukaryotic microorganisms (yeasts) and mammalian cells. Inhibits protein synthesis at the translocation step on the 70S ribosome and causes misreading of the mRNA. Hph, a gene from E. coli, encodes resistance to hygromycin B and can be isol…
The ProteoPlex™ 16-Well Murine Cytokine Array Kit is designed for multiplex detection and measurement of 10 important mouse cytokines in parallel from up to 15 experimental samples. The 10 analytes measured in the kit are pro- and anti- inflammatory cytokines important for the study of immune system regulation and diseases such as asthma and arthritis. Each well on the slide contains a microarray of spotted antibodies with fou…
