Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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MILLIPLEX® MAP Non-Human Primate Cytokine Magnetic Bead Panel

Merck

The MILLIPLEX®MAP Non-Human Primate Cytokine Magnetic Bead Panel is used for the simultaneous quantification of the following Non-human Primate analytes: G-CSF, GM-CSF, IFN-γ, IL-1ra, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12/23 (p40), IL-13, IL-15, IL-17, IL-18, MCP-1, MIP-1α, MIP-1β, sCD40L, TGF-α, TNF-α, VEGF

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MILLIPLEX® MAP Mouse Cytokine/Chemokine Magnetic Bead Panel

Merck

The MILLIPLEX® MAP Mouse Cytokine/Chemokine Magnetic Bead Panel is used for the simultaneous quantification of the following Mouse analytes: G-CSF, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-9, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, IP-10, KC, MCP-1, MIP-1α, MIP-1β, MIP-2, RANTES, TNF-α

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MILLIPLEX® MAP Mouse Cytokine/Chemokine Panel

Merck

The MILLIPLEX® MAP Mouse Cytokine/Chemokine Panel is used for the simultaneous quantification of the following Mouse analytes: Eotaxin, G-CSF, GM-CSF, IFN-γ, IL-10, IL-12 (p40), IL-12 (p70), IL-13, IL-15, IL-17, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IP-10, KC, LIF, LIX, M-CSF, MCP-1, MIG, MIP-1α, MIP-1β, MIP-2, RANTES, TNF-α, VEGF

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MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 22 Plex

Merck

The MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 22 Plex is used for the simultaneous quantification of the following Mouse analytes: GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12 (p70), IL-13, MCP-1, TNF-α, G-CSF, IL-1α, IL-9, IL-15, IL-17, IP-10, KC, MIP-1α, RANTES

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MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 32 Plex

Merck

The MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 32 Plex is used for the simultaneous quantification of the following Mouse analytes: RANTES, MIP-1α, KC, IP-10, IL-17, IL-15, IL-9, IL-1α, G-CSF, TNF-α, MCP-1, IL-13, IL-12 (p70), IL-10, IL-7, IL-6, IL-5, IL-4, IL-2, IL-1β, IFN-γ, GM-CSF, Eotaxin, IL-2, IL-12 (p40), LIF, LIX, M-CSF, MIG, MIP-1β, MIP-2, VEGF

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MILLIPLEX® MAP Mouse Soluble Cytokine Receptor Panel

Merck

The MILLIPLEX®MAP Mouse Soluble Cytokine Receptor Panel is used for the simultaneous quantification of the following Mouse analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4)

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MILLIPLEX® MAP Rat Cytokine/Chemokine Panel

Merck

The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel is used for the simultaneous quantification of the following Rat analytes: Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IP-10, Leptin, MCP-1, MIP-1α, RANTES, TNF-α, VEGF

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MILLIPLEX® MAP Rat Cytokine/Chemokine Panel - Premixed 23 Plex

Merck

The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel - Premixed 23 Plex is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, Leptin, MCP-1, MIP-1α, IP-10, RANTES, TNF-α, VEGF

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MILLIPLEX® MAP Rat Cytokine/Chemokine Magnetic Bead Panel

Merck

The MILLIPLEX® MAP Rat Cytokine/Chemokine Magnetic Bead Panel is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, Leptin, MCP-1, MIP-1α, IP-10, RANTES, TNF-α, VEGF

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Millicell® μ-Angiogenesis Activation and Inhibition Assay Kits

Merck

The Millicell μ-Angiogenesis activation and inhibition kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution.Continuous, live monitoring of cells as tubules formEven, flat slide surface prevents any liquid meniscus from forming, eliminating out-of-focus areasFull well visualization at low magnificationOptimized assay conditions in a miniatur…

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PTEN, active

Merck

PTEN hydrolyzes phosphate at the 3 position on the inositol ring of PtdIns(3,4,5)P3, and Ins(1,3,4,5)P4. Although PTEN has the consensus sequence of a protein tyrosine phosphatase, it dephosphorylates p-nitrophenylphosphate and other synthetic and protein substrates poorly. The greatest catalytic activity has been observed with the highly negatively charged, multiply phosphorylated polymer of (Glu-Tyr)n.

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Staurosporine

Merck

Suitable for use as a potent inhibitor of PKC and other protein kinases in vitro and in cultured cells.

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