Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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iMScope TRIO
Imaging Mass Spectrometry identifies what you see at the molecular level iMScope TRIO transforms your data from just "Observation" to "Analysis". The instrument is a combination of an optical microscope which allows the observation of high-resolution morphological images, with a mass spectrometer which identifies and visualizes the distribution of specific molecules. Superimposing the two images obtained based on these very d…
FAM FLICA® Caspase 1 Assay Kit
Immunochemistry Technologies LLCDetect caspase-1 activity with the FLICA® Caspase 1 Assay Kit. This in vitro assay employs the green fluorescent inhibitor probe FAM-YVAD-FMK to label active caspase 1 enzyme in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry. Caspase 1 (ICE):Members of the mammalian caspase family of cysteinyl aspartate-specific proteases play disti…
Magic Red™ Caspase 3 & 7 Assay Kit
Immunochemistry Technologies LLCMagic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…
RetroNectin® Reagent
Takara BioResearch and Clinical Grade RetroNectin Reagent for Retroviral or Lentiviral Transduction. RetroNectin Reagent for retroviral or lentiviral transduction significantly increases transduction efficiency and results in enhanced gene transfer, especially in suspension and hematopoietic stem cells. RetroNectin Reagent is a chimeric peptide composed of E. coli-derived recombinant human fibronectin fragment that contains three funct…
Mouse ROSA26 safe harbor gene knock-in kit and clones
GeneCopoeiaMouse ROSA26 safe harbor gene knock-in kit and clones. ROSA26 (also known as ROSAβgeo26 locus) in mice genome is first found in chromosome 6 in one particular strain of mice-named ROSAβgeo26-expressed β galactosidase from a randomly inserted transgene at high levels uniformly in nearly all tissues examined. This locus expresses one coding transcript and two noncoding transcripts, and only the non-coding transcripts are disrup…
PureFlex™ process container film
Merck KGaA, Darmstadt, GermanyDesigned to provide strength, flexibility (with maximum resistance to flex-crack), excellent gas barrier performance and inert contact. PureFlex™ Single-use process container films are flexible, robust and chemical resistant materials used in the construction of our single-use process containers, including Mobius® assemblies and NovaSeptum® sterile sampling products.PureFlex film is a high purity, medical grade, coextruded fi…
CRISPR-Cas9 Custom Services
GeneCopoeiaGeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…
MWave 5000 Microwave Synthesis System
Buck Scientific, Inc.The MWave-5000 multifunctional microwave is truly a robust system. The 5000 Integrates microwave synthesis, distillation,concentration, pressurized or non-pressurized reaction, and low temperature microwave reaction into one system. Features: The 5000 has three modes of reaction, under pressure, Normal pressure, and decompressed. Three different sample vessel volumes 300ml, 500ml, and 1 Liter. Variable magnetron outp…
ChIPettor™ System
DiagenodeThe ChIPettor™ System has everything you need for high-quality, fast, and easy chromatin immunoprecipitation for either histones or transcription factor ChIP. Contains a full set of reagents for start-to-finish ChIP starting with 100,000 to 1,000,000 cells (ideal for histone pull down), purification reagents, and a semi-automated pipettor with special resin pipet tips. The ChIPettor™ is designed to stand independently on a 9…
SMART cDNA Synthesis Kits
Takara BioSMART (Switching Mechanism at 5’ End of RNA Template) is a unique technology that allows the efficient incorporation of known sequences at both ends of cDNA during first strand synthesis, without adaptor ligation. The presence of these known sequences is crucial for a number of downstream applications including amplification, RACE, and library construction. While a wide variety of technologies can be employed to take advantag…
PluraScan 2D Bar Code Reader
WHEATONFeatures: Works with WHEATON KeepIT 81 & 100 Boxes and WHEATON CryoELITE Cryogenic Vials and Cryule Ampules Integrated frost reduction system allows multiple racks to be read Flexible software integration Capable of reading bar codes from wide range of manufacturers and label printers Conformance to CE standards 1 year warranty
Magnetic Work Unit
PrimaDiagModule for handling of magnetic beads combining simplicity and efficiency. This innovative module allows replacing the common gripping systems thanks to its patented technology APIM (Attraction Point by Induced Magnetization). Moreover it is provided with a retaining flange allowing using directly your microplates twisted by the heat of the thermal cycler and avoiding any move.The main goal is to focus the magnetic field gene…
The Master 40 Microwave Digestion System
Buck Scientific, Inc.The master 40 will drop kick your samples from the "to be prepped" rack, to the "ready for analysis" rack in no time! Backed by Buck Scientific's legendary customer service, this import from Shanghai is ready to digest samples, and take care of your extractions with the push of a button.
Source BioScience Clones
Source BioScienceWith over 20 million pre-made clones representing nearly every known gene for most common organisms, Source BioScience are your perfect partner for quick and easy solutions for gene and protein expression research. Source BioScience customers can choose from individual pre-made clones or entire clone libraries from many of the most well-known and cited clone consortia and research groups for mammalian and non-mammalian specie…
Source BioScience Antibodies
Source BioScienceSource BioScience have an extensive range of over 200,000 primary and secondary antibodies, recombinant and purified proteins, peptides, ELISA kits, detection kits, western blotting controls, reagents and more. Source BioScience customers can choose from an extensive collection of primary and secondary antibodies assisted by an easily accessible and experienced technical support team. Source BioScience have a reputation for s…
Source BioScience Reagents and Kits
Source BioSciencereSource™ PCR Reagents from Source BioScience offer a range of best-in-class kits and reagents for End Point PCR. By combining enhanced polymerases with highly-developed reaction buffers Source BioScience products deliver optimal results from the simplest to the most challenging of reactions.
Source BioScience Gene Expression
Source BioScienceSource BioScience are a trusted provider of outsourced services for gene expression projects. Source BioScience work with three major microarray platforms (Affymetrix, Agilent and Illumina) and optimise the most suitable array technology for each project.
Source BioScience Stability Storage
Source BioScienceSource BioScience storage suites provide all ICH and unique conditions for stability during storage long term, intermediate and accelerated testing. As manufacturers of the equipment Source BioScience have no limitation on the size or volume of product they can store. Choosing to outsource your stability storage to Source BioScience is a simple process and can reduce your costs and eliminate the need for extra space. Source B…
Source BioScience Stability Storage Equipment
Source BioScienceSource BioScience supply the highest quality environmental equipment including cabinets, chambers, walk-in and reach-in rooms, fridges and freezers which can be manufactured either in the factory or on-site. Source BioScience stability and bio storage equipment is of the highest quality and is suitable for all temperatures and humidity controlled conditions.
Source BioScience Stability Storage Validation
Source BioScienceSource BioScience offer full on-site validation services for environmental rooms and chambers, incubators, refrigerators, freezers and all associated monitoring equipment such as data logging systems and chart recorders. Source BioScience have provided initial and on-going validation services to the pharmaceutical industry for over 12 years and are working with some of the largest pharmaceutical companies in the world. Using…
Master 15 Microwave Digestion System
Buck Scientific, Inc.The Master 15 Microwave digestion system from Sineo with XP-100 Vessels. Here at Buck we love innovative design, the folks at Sineo Microwave (in Shanghai China) have been hard at work for the past 5 years developing the Master 15, which is the most versatile Microwave digestion platform on the market.The Master 15 is able to read all vessel temperatures with it's advanced infrared thermometer. One master vessel is equipped w…
Jupiter Microwave Digestion system
Buck Scientific, Inc.The Jupiter Microwave Digestion systems comes equipped with 1300 Watt of power, 10 100ml vessels and a small footprint. The Jupiter's Safety features are at the top of it's class. The JUPITER series microwave is the culmination of over 20 years of constant innovation in the microwave field. The Jupiter has 1800 watts of variable magnetron power and patented vessels rated at 2250 PSI with a maximum temperature of 300 degrees…
Protective Enclosure
PrimaDiagPrimaDiag provides its ACSIA products line with a protective enclosure. It is available with a ventilated device with HEPA filter for the protection of your samples and a UV radiation device for the decontamination of your workspace.The PrimaDiag enclosure exists in two sizes for the ACSIA and ACSIA XS platforms. It can be customized by adding, in according to your needs, a ventilated device, a UV radiation device or the comb…
PrimaDiag Racks and Accessories
PrimaDiagRacks and accessories for an optimized use of your ACSIA. PrimaDiag provides, with "its turnkey solutions", many racks and accessories allowing optimizing the efficiency and the flexibility of your protocols with ACSIA line platforms. They have been designed and validated by our team to fit with all the requirements of the automation with ACSIA.