Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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PolyMag

OZ Biosciences

For all nucleic acids and all transfection conditions.The universal and powerful PolyMag formulation allows achieving very high transfection efficiency. It is composed by magnetic nanoparticles coated with cationic molecules. Exclusive and optimized PolyMag reagent has been successfully tested with:- All nucleic acids types: naked DNA, RNA, siRNA, ODN, etc…- Cell lines, primary and hard to transfect cells- Adherent and suspens…

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CombiMag

OZ Biosciences

CombiMag improves your transfection reagent efficiencyCombiMag reagent has been designed to be employed in association with all transfection reagents complexed with any types of nucleic acids. All cell types, even hard-to-transfect and primary cells, can be transfected using CombiMag associated to any working reagent, even if its original efficiency is low.CombiMag has been associated with many existing transfection reagents i…

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FlyFectin

OZ Biosciences

FlyFectin ™ is a specifically designed and very efficient transfection reagent for insect cells. Innovative and unique, FlyFectin ™ is: •  Highly efficient with excellent reproducibility•  Multipurpose (various types of nucleic acids)•  Ideal for recombinant protein production with Baculovirus expression system•  Simple, Ready-to-use and Rapid•  Compatible with and without serum-containing culture media•  Non toxic•  Economi…

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Corning® 96-well Clear Round Bottom Polypropylene Not Treated Microplate, 25 per Bag, without Lids, Sterile

Corning Life Sciences

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Sterile and DNase- and RNase-free Total volume is 360 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

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Bradford - Protein Assay Kit

OZ Biosciences

B-Pak, is a straightforward and rapid procedure for determining the concentration of protein in solution. Thanks to an optimized Bradford reagent formulation, B-Pak gives precise determination of protein concentration even in the presence of detergent, allowing the use of this kit for transfection experiments. In addition, this kit can be used for all protein concentration measurement due to a superior linearity of response: f…

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ViroMag

OZ Biosciences

Issued from Magnetofection™ technology, ViroMag is a specific formulation designed to be used in association with all viral vectors and for many transduction applications. For the first time, scientists will be able to increase transduction efficiency, infect non permissive cells, concentrate virus onto cells or in culture medium or synchronize infection without modification of the viruses, just by associating ViroMag reagent…

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miVac Concentrators

Genevac

miVac is a range of centrifugal vacuum concentrators and freeze driers capable of removing water and organic solvents from a variety of sample formats including tubes, microplates, and vials. miVac concentrators come in 2 sizes, the smaller Duo and a larger Quattro. There is a choice of vacuum pump and rotor according to application and sample format.  To speed concentration built-in special runs for working with water and…

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GST and 6HIS tag check kits

Cisbio Bioassays

An easy way to assess tag accessibilityThe production of fusion proteins often raises the issues not only of their structural integrity after isolation, but also of the accessibility of the associated tag. In the case of GST or 6HIS tagged proteins, this verification can be achieved with HTRF® GST and 6HIS check kits. These two assays are competitive immunoassays in which the anti-GST or anti-6HIS Cryptate conjugates bind dire…

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IP-One Assay Kit

Cisbio Bioassays

A new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic advantages of an HTRF® system: totally homogeneous, detection via fluorescence, signal stab…

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Assay Development Service

Cisbio Bioassays

A team of experts for outsourcing your assay developmentsOur Service Team at Cisbio international is highly trained in protein chemistry and fluorescent technology, and offers you its expertise in assay development to build HTRF® assays adapted to your specific targets or to convert existing assays to HTRF® technology.Assays may be developed using HTRF® toolbox reagents, custom labeled molecules or a combination of both. Most…

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DYMENSION 2

Syngene

Rapid Analysis of Multiple 2D Gel Sets DYMENSION 2 has all the features of DYMENSION 1 but has the added ability to detect and compare protein spot maps in multiple gel sets. The software offers many background correction and noise filtering features including a SYPRO® Ruby filter, which can detect and automatically remove spots caused by SYPRO® Ruby crystals adhering to the gel, thus saving users valuable time editing the…

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DYMENSION 3

Syngene

Quick and Easy Analysis of all 2D Gel Applications The exciting DYMENSION 3 software has all the functionality of DYMENSION 2, so can be used to analyse multiple gel sets. In addition, DYMENSION 3 is capable of analysing multi-stained fluorescent gel images stained with up to three contrasting fluorescent labels, for example, Cy™2, Cy™3 and Cy™5. This feature allows users to analyse multiple sets of any type of 2D protein…

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VeroFect

OZ Biosciences

VeroFect™ is a powerful reagent dedicated to the transfection of Vero cells. This lipid -based transfection reagent is issued from the revolutionary Tee-Technology and achieves up to 50-55% transfection efficiency. The complexes formed by DNA and VeroFect™ reagent have an exceptional capacity in destabilizing cell membranes, allowing the delivery of important DNA amounts into cells. VeroFect™ was specifically designed to obtai…

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Corning® 96-well Black/Clear Flat Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during fluorescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…

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Portrait Heat Sealer

REMP AG Laboratory Automation

The REMP Portrait Heat Sealer is a completely electro-mechanical, thermal sealing instrument that does not require any air or vacuum to operate. This versatile and efficient instrument accommodates deepwell, assay, PCR, and standard microplates with only a minor adapter change. The REMP Portrait Heat Sealer uses any of the various rolls of REMP’s Thermo-Seals, most of which are resistant to DMSO, as well as, other solvents and…

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Corning® 96-well EIA/RIA Clear Flat Bottom Polystyrene High Bind Microplate, Individually Wrapped, without Lid, Nonsterile

Corning Life Sciences

High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity of approximately 500ng of mouse IgG/cm2 Ideal for immunoassays Certification results for each lot are made available upon request by contacting local Corning Life Sciences office Recommended working volume of up to 75 to 200 µL Conforms to standard microplate footprint and dimensions Wi…

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SampleScan 1000

The SampleScan1000's combination of a 2D tube reader and LCD display, make this one of the most intuitive single tube scanners available.  Place a tube on top of this unit and it will display the tube's ID number on the easy to read LCD.   A linear bar code scanner is easy to integrate with the SampleScan 1000 software to capture additional 1D bar code data associated with 2D bar coded tubes.   In addition, the SampleScan1000'…

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Pressure Digestion DAB-2/3

Berghof Products + Instruments GmbH

digestec DAB-2/3, to Digest the Hardest Samples. The traditional “stainless steel bomb” with its PTFE insert is being increasingly replaced by the microwave for most routine applications. However, when it comes to difficult-to-digest samples such as silicon carbide or alpha-aluminium oxide, such systems remain of inestimable value to users. The great advantage of these systems lies in the fact that the digestion period can…

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Genom 2005

GSA - Software Development and Analytics

The program "Genom 2005" is a feature rich and user friendly tool to analyse array-experiments.Key Features:Analyse all AffyMetrix-Arrays (cDNA-Arrays or similar technologies could easily be integrated as well) Normalisation of Raw-Data Many additional gene information (official Gennames, Location, Function prediction, Sequences, Database-references (Gene-Ontology, InterPro, SwissPROT ,EMBL, ENSEMBL, LocusLink, OMIM, GeneBank.…

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UltraSpense 2000

KD Scientific

High Throughput Bulk Reagent Dispenser that is Accurate - Affordable - Flexible - Fast Dual plate dispenser for 96 and 384 well plates UltraSpense 2000 is the answer to the increasing demand for an automated yet affordable dispenser for 96 and 384 well microplates. High accuracy and precision dispensing into deep well or low profile microplates, coupled with low dead volume and easy programming makes UltraSpense 2000 the i…

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