Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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INVIEW™ HUMAN EXOME

GATC Biotech

Highlights: Fastest exome sequencing, starting from one sample Applicable for genomic DNA from various sources (tissue, cells, blood and FFPE sample) Special protocol for low-input samples (≥ 10ng) Available under diagnostics standard (ISO17025) INVIEW™ stands for streamlined high-quality next generation sequencing (NGS) solutions for specific applications. Exome enrichment with the latest Agilent SureSele…

4.8/5.0
|3 Reviews

Ion PGM™ Dx System

Thermo Fisher Scientific

Introducing the next-generation sequencing system for the molecular diagnostic laboratory.   The Ion PGM™ Dx Instrument System* will deliver the speed and simplicity of the Ion Torrent™ platform, combined with key workflow advantages designed specifically for regulated laboratory environments and in vitro diagnostic applications. Used in conjunction with Ion PGM™ Dx library kits, Ion One Touch™ Dx template kits,…

5.0/5.0
|1 Review

Normal -(HUVEC) Human Umbilical Vein Endothelial Cells

Lonza Group Ltd

HUVECs cultured in EGM™-Plus Growth Media offer faster proliferation rates while maintaining the same high quality characterization as HUVECs in EGM™ Media. Cryopreserved Clonetics™ HUVEC are shipped as frozen primaries. They are guaranteed through 15* population doublings (*except HUVEC-XL™ guaranteed through 5 PD), express CD31/105, von Williebrand Factor VIII, and are positive for acetyated low density lipoprotein uptake.…

5.0/5.0
|1 Review

SNAP i.d. 2.0 IHC System

Merck

Issues with Your Tissues? Process all Your Slides in a SNAP for Streamlined IHC. The SNAP i.d.® 2.0 Protein Detection System for Immunohistochemistry (IHC) introduces a new capability to the innovative, vacuum-driven SNAP i.d.® 2.0 system. The IHC slide holders allow you to block, probe, and stain up to 12 tissue slides per side (24 slides if both sides are used). Reduced handling time and multiple-slide processing make this…

4.7/5.0
|1 Review

Source BioScience Sanger Sequencing

Source BioScience

Source BioScience have over 15 years of sequencing experience and a unique network of state of the art sequencing laboratories meaning we are perfectly placed to be your local provider for sequencing. Source BioScience have a reputation for providing the highest quality data combined with excellent turnaround times. Pre-paid sequencing vouchers are available for purchase which offer both cost and time savings.

4.8/5.0
|6 Reviews

Source BioScience Next Generation Sequencing

Source BioScience

Source BioScience are one of Europe’s leading providers of commercial sequencing offering services on the most prominent next generation sequencing platforms including the Illumina MiSeq and HiSeq. Source BioScience's next generation sequencing service is Illumina CSPro accredited and operates through a robust quality management system. Customers benefit from both excellent service and rapid turnaround times. Source BioScienc…

5.0/5.0
|1 Review

Thermo Scientific NE-PER Nuclear and Cytoplasmic Extraction Kit

Thermo Fisher Scientific

Prepare concentrated nuclear extracts for an EMSA and gel shift assays. The Thermo Scientific NE-PER Nuclear and Cytoplasmic Extraction Kit provides for efficient cell lysis and extraction of separate cytoplasmic and nuclear protein fractions in less than two hours. The NE-PER Kit is a nuclear protein extraction method that involves simple, stepwise lysis of cells and centrifugal isolation of nuclear and cytoplasmic protein f…

4.5/5.0
|4 Reviews

Evolution Purge and Trap Concentrator

EST Analytical

EST Analytical continues to be the innovator of purge and trap technology with the Evolution purge and trap concentrator. Designed to be robust, the system includes patented features to reduce carryover and dramatically improve sample throughput. EST Analytical provides complete application and hardware support with a team of chemists that are fully trained on the purge and trap system, as well as the GC/MS making EST Analyti…

5.0/5.0
|2 Reviews

E-Cube™ Culture System Kit (without CellCube® Module)

Corning Life Sciences

The E-Cube™ System is a simple bioreactor with 8,500 cm2 cell growth area for growing anchorage dependent cells in only a 25.4 cm x 35.6 cm footprint. Cells grow in Corning’s parallel-plate CellCube® Module on the same treated polystyrene used in Corning culture vessels. The E-Cube™ System kit consists of an oxygenator, medium reservoir, multiple access ports, and all required tubing and fittings; CellCube® Modules must be p…

4.7/5.0
|1 Review

Corning® CellBIND® Surface 35 mm Culture Dish

Corning Life Sciences

Approximate growth surface area is 9 cm2 Actual inside growth surface diameter is 34.4mm Height is 10mm Manufactured from optically-clear virgin polystyrene Corning® CellBIND® surface treated for optimal cell attachment Sterilized by gamma radiation and certified nonpyrogenic Have stacking beads to aid in handling Supplied with vents to provide consistent gas exchange

5.0/5.0
|1 Review


Corning® 384-well Low Flange Black Flat Bottom Polystyrene NBS Microplate, 10 per Bag, without Lid, Nonsterile

Corning Life Sciences

(This is the suggested replacement for 3654) Black wall plates have reduced autofluorescence, higher signal to background ratio and lower CV's. Nonbinding (NBS) surface is a Corning proprietary treatment technology used on polystyrene microplates to create a nonionic hydrophilic surface (polyethylene oxide-like) that minimizes molecular interactions Ideal for reducing protein and nucleic acid binding at low concentrations,…

4.7/5.0
|1 Review

Corning® 96-well Clear Flat Bottom Polystyrene NBS Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Nonbinding (NBS) surface is a Corning proprietary treatment technology used on polystyrene microplates to create a nonionic hydrophilic surface (polyethylene oxide-like) that minimizes molecular interactions Ideal for reducing protein and nucleic acid binding at low concentrations, and increasing assay signal to noise Without lids, lids supplied separately Recommended working volume of up to 75 to 200 µL Conforms to stan…

5.0/5.0
|2 Reviews

Corning® 1536-well White Polystyrene TC-treated Microplate, 10 per Bag, with Lid, Sterile

Corning Life Sciences

(This is the suggested replacement for 3855 and 353381)Excellent signal dynamic range due to low background fluorescence and enhanced signal intensitySuperior flatness minimizes variability within a plate and between platesFlat bottom wells are compatible with automated dispensers including the PerkinElmer FlexDrop™TC-treated for optimal cell attachmentWorking volume of up to 10 µL"

5.0/5.0
|1 Review

Corning® 384-well Black/Clear Round Bottom Ultra-Low Attachment Spheroid Microplate, Bulk Packed 10 per Bag, with Lid, Sterile

Corning Life Sciences

Ultra-Low Attachment microplates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation and cellular activation Surface is noncytotoxic, biologically inert and nondegradable Sterilized by gamma irradiation Black wall microplates have low background fluorescence, minimal light scatter and reduced crosstalk Opaque walls to prevent wel…

5.0/5.0
|1 Review

Corning® 96-well Clear Round Bottom Ultra-Low Attachment Microplate, Individually Wrapped, with Lid, Sterile

Corning Life Sciences

Ultra-Low Attachment surface with covalently bonded hydrogel that minimizes cell attachment, protein absorption, enzyme activation and cellular activation The surface is noncytotoxic, biologically inert and nondegradable Round bottoms with 330 µL total volume Recommended working volumes of 75 to 200 µL Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrog…

4.7/5.0
|2 Reviews

Falcon® 48-well Clear Flat Bottom TC-treated Cell Culture Plate, with Lid, Individually Wrapped, Sterile, 50/Case

Corning Life Sciences

Flat bottom, with low evaporation lid. Individually wrapped, sterile, 50/case. Unique labyrinth lid, condensation rings, and deep-well design control contamination, reduce evaporation, and minimize edge effects.Reliable vacuum-gas plasma tissue culture treatment provides well-to-well and plate-to-plate consistency. Crystal-grade virgin polystyrene Nonpyrogenic Standard tissue culture (TC)-treated Convenient, peel-open medi…

5.0/5.0
|1 Review

Corning® Primaria™ 75cm² Rectangular Straight Neck Cell Culture Flask with Vented Cap

Corning Life Sciences

Unique nitrogen-containing tissue culture surface chemistryImproves attachment, spreading, and growth for many primary cells or cell linesCrystal-grade polystyrene modified by proprietary vacuum gas plasma treatment processStable, permanent surface modificationOptically clearNo special storage requiredSamples from each lot of Corning Primaria products are analyzed by Electron Scanning for Chemical Analysis (ESCA)Packaged in re…

5.0/5.0
|2 Reviews

Corning® ITS Premix Universal Culture Supplement, 20 mL, 1/Pack

Corning Life Sciences

Corning® ITS Universal Culture Supplement, 20 mL, contains insulin, human transferrin, and selenous acid, the three most universally essential components of defined culture media. The concentrated supplement stimulates cell proliferation of a variety of cells under serum-reduced conditions. 20 mL (20L equivalent), 1/packThe ITS Premix (354350 and 354231) contains the following when used at the recommended dilution: Insulin (5u…

5.0/5.0
|1 Review

Corning® BioCoat™ Matrigel® Invasion Chamber with 8.0 µm PET Membrane in four 6-well Plates, 6/Pack, 24/Case

Corning Life Sciences

Corning® BioCoat™ Matrigel® Invasion Chamber with 8.0 µm PET Membrane in four 6-well Permeable Supports are packaged ready to use in Falcon® Companion Plates, 24/case. Corning BioCoat™ cell culture inserts are pre-coated with extracellular matrix proteins for applications requiring a protein-coated cell surface, such as cell adhesion, growth, invasion, migration and/or differentiation.Storage: -20°C; Shelf life: >= 3 months fr…

5.0/5.0
|1 Review

Corning® 2 mL Assorted Colors Internal Threaded Polypropylene Cryogenic Vial, Self-Standing with Round Bottom

Corning Life Sciences

2 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…

4.9/5.0
|3 Reviews