Drug discovery > Target Discovery Products & Reviews

NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)

Epigenetic modifier; Inactivates O6-alkylguanine-DNA Alkyltransferase (AGT)

Inducer of OCT4 expression

Inhibitor of microtubule formation

MEK/ERK pathway inhibitor; Inhibits MEK

Tyrosine kinase inhibitor; Inhibits FGFR

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

PKC pathway activator; Activates protein kinase C

p53 inhibitor

PI3K and MEK/ERK pathway inhibitor; Inhibits RasGAP and ERK1

Oleic acid biosynthesis pathway inhibitor; Inhibits stearoyl-CoA desaturase (SCD1)

MEK/ERK pathway inhibitor; Inhibits B-RAF

Tyrosine kinase inhibitor; Inhibits LCK, FYN, HCK, and SRC

Prostanoid pathway activator; Activates prostaglandin receptors EP1, EP2, EP3 and EP4

Hedgehog pathway activator; Activates Smoothened (SMO)

Antibiotic; Protein synthesis inhibitor

Cyclin/CDK pathway inhibitor; Inhibits CDKs

Integrin and tyrosine kinase activator; Activates Integrin, FGFR, IGFR and HER2

NF-?B pathway inhibitor; Inhibits NF-?B

mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases

Immune modulator; TLR7 and TLR8 agonist

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