Drug discovery > Target Discovery Products & Reviews

Ectodomain, stabilized prefusion conformation, resistant to furin cleavage

HEK293 expressed, high ACE-2 binding  

Tn5 insect cell expressed, high ACE-2 binding  

HEK293 expressed, high ACE-2 binding  

Sf21 insect cell expressed, over 95% purity  

SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that are commonly comprised of four structural proteins. One of the proteins, SARS-CoV-2 Spike Protein (S Protein), is a glycoprotein that mediates membrane fusion and viral entry, and as such is a crucial COVID-19 target.  R&D Systems SARS-CoV-2 Spike range of bioactive proteins are valida…

CHO expressed. GCN4-IZ trimerization domain. Prefusion Conformation. High ACE-2 binding  

South African Variant  

UK Variant. Resistant to Furin & Stabilized Prefusion Conformation

Brazilian Variant

Guaranteed editing with predesigned gRNA designs

Use our proprietary algorithms to design custom Cas9 guide RNAs

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Guide RNAs (gRNAs) contain the target-specific sequence for guiding Cas9 protein to a genomic location.

Hybridizes to crRNA to activate the Cas9 enzyme.

Hybridizes to crRNA to activate the Cas9 enzyme.

urified carrier DNA that improves delivery of Cas9 ribonucleoprotein (RNP) by electroporation.

Purified carrier DNA that is required for efficient delivery of Cpf1 ribonucleoprotein (RNP) by electroporation.

For detection of on-target or known off-target CRISPR events in cultured cells

An advanced data analysis pipeline for quantifying your genome editing results

Highly multiplexed, targeted amplicon sequencing for critical analysis of your CRISPR edits

NGS-ready amplicon libraries. Fast. Easy. Convenient.

A small molecule compound that has demonstrated an ability to increase the rate of homology-directed repair (HDR).

Deep, targeted amplicon sequencing with highly multiplexed panels for sequencing on Illumina platforms.