Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Bacterial Gene Editing with CRISPR

Merck

CRISPR/Cas9-mediated recombineering is the most powerful bacterial genome engineering method to date. In addition, Cas9-mediated recombineering overcomes the dependence on a second recombination step, avoids the creation of destabilizing scar sites, can be used in multiplexing, and is less time-consuming than previous protocols.

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CRISPR Vectors and Controls

Merck

Compare and contrast the features of a wide variety of guide RNA (gRNA) and Cas9 products for in vitro and in vivo CRISPR experiments. Select the best formats for your mammalian or plant applications: SygRNA ® synthetic gRNA, plasmid DNA, lentiviral particles, and proteins.

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i-Ome® Discovery Protein Array

Standard BioTools Inc.

The i-Ome Discovery Protein Array uses the patented KREX® protein folding technology to enable accurate and reproducible profiling of patient samples against more than 1800 carefully selected full-length, properly folded proteins. Curated content focused on known and potential autoantigens helps facilitate biomarker discovery with significantly lower false discovery rates and smaller sample sizes than other technologies. The…

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AAV9 Probes

Gator Bio

The Gator ® AAV9 Probes are high specificity nanobody-based biosensors that enable direct capture and quantitation of AAV9 in crude lysates, column eluates, cell lysates and cell culture supernatants. The Gator ® AAV9 probe uses proven CaptureSelect™ (Thermo Fisher Scientific) high affinity and high specificity anti-AAV9 nanobody.

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Refeyn TwoMP

Refeyn

Refeyn's TwoMP mass photometer measures the mass of single biomolecules in solution and without labels - for studies of protein interactions, oligomerisation and macromolecular assembly, and assessment of sample purity.

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TwoMP Auto

Refeyn

The TwoMP Auto combines the ease and efficiency of automation with the unmatched sensitivity and simplicity of Refeyn’s molecular mass measurement technology. It frees up operator time and offers enhanced precision, enabling rapid measurement of multiple samples with low sample consumption.

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Supelco® Smart SPME Fibers

Merck

Our Smart SPME fibers are equipped with a unique Smart chip that offers traceability, ease-of-use, and increased productivity. The smart SPME fibers are an extension of our expertise and innovation from traditional SPME coatings to smart SPME format for accurate, reliable, and consistent results.

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Supelco® Overcoated (OC) SPME Fibers

Merck

The over coating of fibers is a new technology in fiber coating to protect the SPME fiber from matrix components. This allows for immersion of the fiber directly into complex samples ensuring a more efficient extraction (e.g. of semivolatile compounds). Polydimethylsiloxane (PDMS) is used to overcoat a PDMS/divinylbenzene (DVB) fiber. The resulting fiber is more physically robust and resistant to chemical fouling and allows f…

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Supelco® Nitinol Core SPME Fibers

Merck

The nitinol-core of SPME fibers enhances the fiber performance and the precision of chromatographic results to enhance lot-to-lot and fiber-to-fiber reproducibility, increase fiber durability, and maintain selectivity and inertness compared to fused silica core fibers.

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Nitric Acid, Ultratrace

Spectrum Chemical

The cannabis industry uses ICP-MS and AA to test for heavy metals. Nitric Acid, Ultratrace from Spectrum Chemical is a strong, highly corrosive mineral acid with extremely low metal content (over 50 with levels less than 100 PPT) ideal for this purpose due to its primary use as an analytical reagent in elemental analysis determinations using ICP and AA techniques, digestion of water samples, and as a doping agent for organic…

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Cryo Vial External

Abdos

Description- Abdos Cryo Vial external thread are manufactured using high purity virgin USP Class VI Medical grade polypropylene (PP) conforming to US FDA 21 CFR, free from natural rubber & heavy metal. Abdos Cryo Vial is designed for long-term cryogenic storage of biological samples, all type of cells and any enzymes or reagents. It’s leak-proof cap design and strong wall thickness makes it an ideal product for transpo…

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Cryo Box (Polycarbonate)

Abdos

Made of strong polycarbonate and designed to be used at a temperature between -196°C to 121°C. Can be used in gas phase of liquid nitrogen with appropriate safety procedure in place. Transparent lids permit viewing of contents. These boxes create small, space-efficient storage system within a large mechanical freezer. Lids have numbered grid for sample identification. The surface of the lid has a frosted area suitab…

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