Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Human Protein S-Nitrosylation Array G1

RayBiotech Inc.

The RayBiotech G-Series Human Protein S-Nitrosylation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of cystein s-nitrosylation of 507 different human proteins cell lysate, culture supernatant, serum, plasma and other biological samples.

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Human Protein Oxidation Array G1

RayBiotech Inc.

The RayBiotech Human Protein Oxidation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of oxidation of 507 different human proteins in cell lysate, culture supernatant, serum, plasma and other biological samples.

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Human Protein S-Acylation Array G1

RayBiotech Inc.

The RayBiotech Human Protein S-Acylation Antibody Array 1 is a multiplex assay on glass slide for the relative detection of cystein s-acylation of 507 different human proteins cell lysate, culture supernatant, serum, plasma and other biological samples.

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Assay development and screening

Selvita

Selvita provides its clients with effective drug discovery support based on broad capabilities and deep expertise in small molecule drug discovery. The in vitro pharmacology support offering at Selvita covers drug discovery phases from target validation through to preclinical candidate selection. We provide a versatile protein-to-cell approach for the development of pharmacologically active compounds and biologics.

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ICPMS-2040/2050 Series

Shimadzu Corporation

The ICPMS-2040 Series and ICPMS-2050 Series inductively coupled plasma mass spectrometers (ICP-MS) provide approximately twice the sensitivity of conventional models through the use of a uniquely designed plasma torch (a mechanism to generate plasma). 

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AD3220 Aspirate / Dispense Platform

BioDot Inc.

BioDot’s AD3220 system is designed for high-speed aspirating and dispensing applications to glass slides, microtiter plates, membranes or any custom surface. This tabletop platform is ideal for R&D environments, but still provides enough dispense area for pilot scale production. Dispensing technology, number of channels and deck options enable customization to meet multiple application needs.

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CellWriter™S

BioDot Inc.

The CellWriter™ S robotic workstation produces slides for Karyotyping, FISH and FFPE. Utilizing BioDot’s nanoliter dispensing technology (BioJet) with temperature and humidity control, the CellWriter S simplifies and automates the dropping process to efficiently deliver quality spread interphase and metaphase nuclei for analysis. FISHArray™ enables multiplexed FISH assays and eliminates the need for rubber cement when prepari…

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BioJet™

BioDot Inc.

This proprietary, quantitative, non-contact technology couples the BioJet “Drop-on-Demand” valve with a high-resolution syringe pump. The BioJet meters precise amounts of reagent, incorporating the benefits of non-contact dispensing and the ability to program exact drop volumes.

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Raimaker™

BioDot Inc.

The Rainmaker features BioDot’s proprietary non-contact piezoelectric low volume dispensing technology and allows users to select a wide range of volumes as a single drop or high-frequency burst. Liquid volumes, from picoliters to nanoliters, can be dispensed On-the-Fly or in Step-and-Repeat mode. Rainmaker’s On-the-Fly printing supports multiple tip dispensing to discrete locations for true high-speed arraying.

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PURASPIN®

FILTROX AG

PURASPIN ® depth filtration units are designed for small scale filtration trials. They allow efficient and cost-effective depth filtration of up to 20 mL. They can be used as a depth filter unit in a centrifuge or by applying vacuum.

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PURACAP® and PURACAP® BIO SD

FILTROX AG

PURACAP ® and PURACAP ® BIO SD are filter capsules for lab and pilot scale filtration trials. The capsules are used as a tool to generate the data needed for a propper scale-up. PURACAP ® is used for standard depth filtration (sheet filtration), PURACAP ® BIO SD for alluvial filtration (e.g. clarification of cell broth).

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ACTIVASORB® sheets, modules and caps

FILTROX AG

ACTIVASORB ® depth filter sheets are used in various applications such as decolorization, deodorization or catalyst removal. This type of filter sheets contains immobilized activated carbon which allows a easy and clean handling. In addtion, treatment with immobilized activated carbon is much more efficient compared to loose carbon powder due to a forced contact of the impurities with the activated carbon.

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PURASPIN® Test Kit

FILTROX AG

The PURASPIN ® Test Kit contains 5 different filter sheet types for laboratory filtration tests for coarse, fine, clarifying and sterile filtration. A practical and easy-to-use tool to define the right filtration solution at an early stage in the development process.

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Scale-up Test Kit

FILTROX AG

The SCALE-UP Test Kit is a tool to find the ideal depth filter at an early stage of the process development. The test kit contains 10 different PURASPIN ® for 20 mL trials, a 2" capsule with a selection of filter sheets for verification and the necessary information for a proper scale-up calculation.

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AAV Ratio Kit

Gator Bio

The Gator ® AAV Ratio Kit enables empty vs full determination of AAV serotypes 1-10 and chimeric serotypes in crude and purified samples. The AAV Ratio Kit includes: AAVX probes (96 probes/tray) SSB probes (96 probes/tray) Lysis Buffer DNA Detection Solution AAV Ratio Substrate Q Buffer SS DNA Standard Lysis tubes ** Contains temperature sensitive components. Must be shipped overnight. **

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In vivo pharmacology and toxicology

Selvita

Selvita’s in vivo team has long standing experience in the areas of infection, inflammation and fibrosis and has contributed to numerous  preclinical and clinical candidates.  Over 60 animal models in mice, rats, and rabbits are fully characterized and validated with clinically relevant pharmacological controls whereas in-depth expertise in translational biomarker selection and validation gives confidence in the smooth transi…

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