Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Costar® Spin-X® Centrifuge Tube Filters, 0.45 µm Pore CA Membrane, Sterile, 96/Case

Corning Life Sciences

These Costar® Spin-X® centrifuge tube filters have a 0.45 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Sterile and certified nonpyrogenic and DNase-/RN…

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Corning® 96-well Clear V-Bottom Polystyrene Not Treated Microplate, Individually Wrapped, without Lid, Sterile

Corning Life Sciences

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm² Without lids, lids supplied separately Total volume is…

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Corning® 96-well Half Area Clear Flat Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Total volume is 190 µL; recommended working volume of up to 25 to 125 µL Conforms to standard microplate footprint and dimensions Without l…

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HistoChoice Clearing Agent

NBS Biologicals Ltd.

HistoChoice Clearing Agent is a much less hazardous replacemnt for xylene/toluene.  Ton-toxic, non-carcinogenic, non-flammable, vistually odourless and non-irritating to human skin, faster wax dissolution, slower evaporation than xylene.

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Corning® 1700cm² Expanded Surface Polystyrene Roller Bottle with Easy Grip Cap, 5 per Bag, 40 per Case

Corning Life Sciences

Ribbed design provides twice the surface area with the same exterior dimensions. Bottles are manufactured from virgin polystyrene, caps from high density polyethylene Both resins meet the USP Class VI requirements for plastic containers and closures Treated for optimal cell attachment One piece seamless construction with printed graduations Printed lot numbers to aid in product traceability Sterilized by gamma radiatio…

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Corning® 96 Half Area Well Solid White Flat Bottom Polystyrene TC-treated Microplates, 20 per Bag, with Lid, Sterile

Corning Life Sciences

This microplate has half the growth area of a standard 96 well plate Flat bottoms with 190 µL total volume White walled plates enhance luminescent signals and have low background luminescence and fluorescence Opaque walls to prevent well-to-well crosstalk Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Bulk packed 20 per bag

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Corning® 96-well Solid White Flat Bottom Polystyrene TC-treated Microplates, 25 per bag, without Lid, Sterile

Corning Life Sciences

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Flat bottoms with 360 µL total volume Recommended working volumes of 75 to 200 µL Treated for optimal cell attachment Without lids, lids supplied separately Sterilized by gamma radiation and nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 25 per bag

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Corning® 96-well White/Clear Flat Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Nonsterile

Corning Life Sciences

Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescent and enabling readings down to 340nm Designed to reduce well-to-well crosstalk during luminescent assays Can be used for both top and bottom reading instruments Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the i…

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Corning® 96-well Clear V-Bottom Polypropylene Not Treated Microplate, 25 per Bag, without Lids, Nonsterile

Corning Life Sciences

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Certified DNase- and RNase-free Total volume is 320 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately

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Corning® Large Cell Scraper

Corning Life Sciences

Useful for the mechanical harvesting of cells Blade design minimizes cell damage and ensures even contact with the growth surface Designed for use in large flasks and roller bottles Individually wrapped Sterilized by gamma radiation and certified nonpyrogenic

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HTRF® KinEASE™ TK

Cisbio Bioassays

Cisbio's HTRF® KinEASE™ platform has expanded to include a universal assay for tyrosine kinases. The HTRF KinEASE TK assay is based on our patented HTRF technology and uses a unique tyrosine peptide substrate in combination with a Europium-labeled monoclonal antibody. The HTRF KinEASE™ TK assay has been validated on 59 tyrosine kinases to-date including both receptor and cytoplasmic TKs. A proprietary substrate stabilizing buf…

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CLC Combined Workbench Software

CLC bio

CLC Combined Workbench includes all features and functions of CLC Free Workbench, CLC Protein Workbench, and CLC Gene Workbench. The program sets new standards for bioinformatics software with its overall graphical display and usability driven, user-friendly interface. In addition, it features a number of unique and innovative bioinformatics tools for supporting advanced biochemistry and molecular biology lab research. CLC Com…

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CLC MLST Module

CLC bio

CLC bio presents its new software module for Multilocus Sequence Typing (MLST). MLST is a portable and precise state-of-the-art technique for typing bacteria and yeast isolates. It is based on DNA sequence data from a number of house-keeping genes. For each gene, the experimental data is compared to a database of known alleles and a fi nal sequence type is assigned by combining information from all genes. Easy The CLC MLST Mod…

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GreenScreen HC

Gentronix Ltd.

Gentronix has launched a new, accurate and fast in vitro mammalian cell genotoxicity assay - GreenScreen HC. The TK6 host cells are p53 competent and familiar to most genetic toxicology laboratories. A patented GFP reporter system exploits the proper regulation of the GADD45a gene. The assay delivers both high specificity and high sensitivity and detects all common mechanistic classes of genotoxin. The 96-well microplate for…

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Demecolcine

CHEMOS GmbH

Demecolcine Synonyms: N-Deacetyl-N-methylcolchicine 6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)benzo[a]heptalen-9(5H)-one N-Methyl-N-desacetylcolchicine Colchamine Santavy’s substance F CAS No.: 477-30-5 Molecular formula: C21H25NO5 Physical Appearance:Slightly yellow powder Purity: >98% (sum of enantiomers by HPLC) Soluble in: acidified water, alcohol, ether, chloroform Product Description: Used to immobilize chromosome…

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IP-One ELISA assay kit

Cisbio Bioassays

IP-One ELISA assay kit from Cisbio Bioassays - Simple and highly accurate measurement of IP1 IP1, a downstream metabolite of IP3, accumulates in cells following activation of Phospholipase C (PLC) coupled receptors. Among them, the Gq coupled GPCRs represent the most important family of receptors which can activate the β subtype of the PLC family. Other receptor types, like protein tyrosine kinase receptors, antigen or immuno…

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TV200 Standard Twin-Plate Wide Format Mini-Gel Electrophoresis Unit

Scie-Plas Ltd

The TV200 twin-plate 20.5 x 10cm (W x H) wide format mini-gel units are designed specifically for PAGE techniques requiring tape-cast gels or gels cast within the TV200-MC2 2-gel and TV200-MC10 10-gel multicasters, which are also available through Scie-Plas.A 20.5cm gel width allows the user to separate twice the number of samples within a single gel, thereby eliminating the problems borne from comparing samples resolved in 2…

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TV200Y Standard Twin-Plate Wide Format Mini-Gel Electrophoresis Unit

Scie-Plas Ltd

The TV200Y twin-plate 20.5 x 10cm (W x H) wide format mini-gel unit includes, as standard, a precision engineered casting base, which acts in conjunction with our recently modified TV200-GRM to provide simple, leak-free casting.Twin screws, located on each gel clamp within the GRM, work in tandem with a dovetailed silicone gasket to distribute pressure evenly along the height and breadth of the gel, while glass plate stops loc…

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CLC RNA Workbench Software

CLC bio

With the all new CLC RNA Workbench, CLC bio brings you complex analysis of RNA molecules in a fully integrated, user-friendly and graphically advanced bioinformatics framework. Advanced The CLC RNA Workbench gives the user easy access to a range of complex algorithms and options. RNA secondary structures can be predicted using state-of-the-art free energy minimization algorithms and parameters, thermodynamic and statistical d…

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Sample Vials and Accessories

Waters

Waters offers a broad range of vials, each one is held to tight dimensional tolerances and the certified products have cleanliness measured by LC and MS.LC/GC Certified vials are tested by LC/UV for residues of chemicals used in processing and packaging vials. The septa are tested by headspace GC to ensure low levels of low molecular weight polymer. These vials are suited for analyte concentration in the µg/mL concentration; t…

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IdentityE High Definition Proteomics system

Waters

The Waters IdentityE High Definition Proteomics system defines the new standard for rigorous protein identification. The IdentityE High Definition Proteomics System is an UltraPerformance LC® (UPLC)/High-Bandwidth Mass Spectrometry (MS E) system solution suitable for confident protein identification designed to meet stringent requirements as outlined by leading scientific journals.The new Waters IdentityE High Definition Pro…

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