Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent…
3M bioanalytical's Empore c18 90 Disk-Commonly used for the solid phase extraction of analytes from complex sample matrices. A variety of functional groups, such as octadecyl (C18) and octyl (C8) can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular me…
SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction. SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction.
SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic. SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites. SDB-RPS is also u…
3M Bioanalytical's Anion-SR is a poly(styrenedivinylbenzene) copolymer that has been modified with quaternary ammonium groups. Note that the 3M Anion-SR is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The functional group imparts unique selectivity for anionic analytes, such as Endothall, Dalpon and haloacetic acids.
The Oil & Grease Disk was specifically designed for EPA Method 1664 (N-Hexane Extractable Materials (HEM) and Silica Gel Treated N-Hexane Extractable Material (SGT-HEM) by Extraction and Gravimetry). EPA Method 1664 Revision A was approved for use in the United States and published in the Federal Register on May 14, 1999. The Oil & Grease Disk incorporates C18 sorbent particles within a hydrophobic matrix. For EPA Method 16…
Empore Carbon Disks are designed for the extraction of volatile, highly polar, and water soluble compounds from aqueous solutions. The Empore Carbon Disk provides all the advantages of activated carbon in a compact and thin Empore Disk.
Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.
Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.
This mixed phase chemistry, in which two primary modes of attraction are present, allows for a more efficient and selective extraction compared to traditional reversed phase techniques. Neutral and ionized analytes can be simultaneously extracted from a complex mixture and eluted as separate fractions. A mixed phase sorbent offers the following advantages: Eluting acidic and neutral analytes separately from basic analy…
This chemistry promotes high retention of a wide range of analytes, reducing method development time and facilitating a generic approach to sample preparation.
Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.
Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.
This mixed phase chemistry, in which two primary modes of attraction are present, allows for a more efficient and selective extraction compared to traditional reversed phase techniques. Neutral and ionized analytes can be simultaneously extracted from a complex mixture and eluted as separate fractions. A mixed phase sorbent offers the following advantages: Eluting acidic and neutral analytes separately from basic analyt…
This chemistry promotes high retention of a wide range of analytes, reducing method development time and facilitating a generic approach to sample preparation.
The Empore™ High Performance Extraction Disk Plate differs in design from plates offered by other manufacturers and requires a specific vacuum manifold. Manifolds supplied by different plate manufacturers are specific to the design of their plates and cannot generally be used with plates from other manufacturers. In some cases, the use of spacers to raise/lower the height of a collection device inside the manifold may overco…
Replacement gaskets are available with the vacuum manifold assembly. The gasket can become worn over time and the seal between the plate and the manifold will be affected. This may result in poor vacuum pressure and negatively effect flow rates. The gasket should be checked regularly and replaced when it becomes worn.
EmporeTM Tape Pads are intended for sealing unused portions of a 96-well solid phase extraction plate during vacuum processing to enable vacuum to be uniformly applied to each well being used. Use a clean sheet each time for maximum sealing ability. Note: these tape sheets are not intended for sealing collection plates prior to sample injection because the adhesive may clog the injection needle.
Empore Filter Aid 400 has been shown to improve flow rates and recoveries for separation and filtration of water samples containing suspended solids. When placed on top of the Empore™ Extraction Disk at a depth of about 1 cm, Empore™ Filter Aid 400 acts as depth filter to inhibit the migration of suspended solids to the surface of the disk. This reduces extraction time and improves rates and recovery of analytes.
The Scorpion range offers the user the ability to step up to automated plate handling with a number of OEM liquid handling systems.
The PX Scanner is the revolutionary new product from Oxford Diffraction which has been designed specifically for the identification and analysis of protein crystals in situ within multi-well crystallisation plates. The PX Scanner is unique, having both an optical and an X-ray imager in one system. The optical imaging component allows the user to visually locate and select objects for X-ray analysis. Accepting a wide range of c…
Agilent Bio-Monolith HPLC columns provide high resolution and rapid separations of antibodies (IgG, IgM), plasmid DNA, viruses, phages and other macro biomolecules. The product family offers strong cation exchange, strong and weak anion exchange, and Protein A phases.
