Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Mouse Geniom Biochip

febit holding GmbH

The biochip from febit enables up-to-date profiling and enrichment of genes and SNPs of interest using Gene Expression Profiling, SNP-Detection, ncRNA analysis as well as targeted enrichment of genes for Next-Generation Sequencing (NGS).

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Cell-based ELISA

Bio-Techne

R&D Cell-Based ELISA - Dual fluorescence detection of two biomolecules simultaneously in the context of a whole cell R&D Systems Cell-Based ELISAs permit the simultaneous detection of two proteins in the same microplate well without the need for lysate preparation. Cell-Based R and D ELISA Kits come in two formats: phospho-protein kits contain antibodies to measure both the phosphorylated and the total protein, while total p…

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ATPase or GTPase Assay Kits

Innova Biosciences Ltd.

Feel the need for speed in your lead development time? The Answer – High Through Put Screening ATPase or GTPase Assays from Innova Biosciences. Is your drug discovery program for ATPase or GTPase enzymes holding you back? Still searching for an inhibitor? Then you need Innova Biosciences easy to use, GTPase or ATPase assay kits. The non radioactive colorimetric assay kits use a 96 well format, and all the necessary reagents ar…

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Vision Life Science Spectrophotometer

Hoefer Inc. Europe

The Vision diode array spectrophotometer offers 16 predefined methodologies for nucleic acid quantification (DNA, RNA, and oligonucleotides), protein assays (BCA, Biuret, Bradford, and Lowry) and for cell culture density measurements. Additionally, the Vision can accomodate up to 90 custom protocols. The visualization of the nucleic acid scan with the full graphic display is particularly useful, especially for RNA samples wh…

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BlueScreen HC: The luminescent adaptation of GreenScreen

Gentronix Ltd.

BlueScreen HC is based on the fast, accurate GreenScreen HC genotoxicity assay from Gentronix Ltd. BlueScreen HC uses the same human-derived, p53-competent TK6 cells to host a patented reporter system that exploits the proper regulation of the GADD45a gene. However, in place of GFP, BlueScreen HC utilizes a luciferase from the marine copepod Gaussia princeps to generate a luminescent output. The BlueScreen luminescent assa…

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Thermo Scientific Synaptogenesis Kit

The Synaptogenesis Kit enables simultaneous detection of neuronal population, neurite, pre-synaptic vesicle, post-synaptic puncta and synapse using a fixed end-point assay based on immunofluorescence detection in cells grown on standard high-density microplates.

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TaqMan® Protein Expression Assays

Thermo Fisher Scientific

TaqMan® Protein Expression Assays help quantitate protein expression using gold standard TaqMan® 5' nuclease chemistry with a workflow and sample quantity similar to our TaqMan® Gene Expression and MicroRNA (miRNA) Assays. As the protein expression results are obtained on the same analytical platform, these revolutionary assays enable direct correlation of mRNA and/or miRNA expression to protein expression.

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Thermo Scientific ABgene Diamond Ultra 384-well PCR Plate

Thermo Fisher Scientific

The Thermo Scientific ABgene 384-well Diamond PCR Plate is the world's most rigid 384-well PCR plate and has specifically been developed for reliable performance on high-throughput robotic handling systems. The uniform thin-wall design has been optimized for use in PCR and QPCR applications but also offers the advantage of delivering superior resistance to warping during PCR cycling, thus reducing evaporation issues associat…

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Thermo Scientific Pinpoint software

Thermo Fisher Scientific

Thermo Scientific Pinpoint software is designed to simplify the transition from early-stage biomarker discovery to larger-scale, quantitative verification of putative biomarkers and general quantitative proteomics. It takes advantage of the power of Thermo Scientific TSQ triple quadrupole mass spectrometers to generate high-confidence quantitative data. Pinpoint software is in final stages of development; but for a limited t…

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VX-200 Vortex Mixer

Labnet International

Continuously variable speed makes the Vortex Mixer VX-200 useful for a variety of applications, from gentle mixing to resuspending pellets. The unit has a circular orbit, rather than the elliptical orbit found on many other vortexers. This allows a vortexing motion to be achieved even at low Many speeds, a task that cannot be accomplished with eliptical orbit units. Many vortex mixers prevent excessive vibration with added wei…

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Cellul'erk - HTRF assay

Cisbio Bioassays

Cisbio Bioassays has developed Cellul'erk, a highly accurate HTRF assay for measuring phosphorylated ERK1/2 in 96-, 384- and 1536-well formats providing for an HTS compatible assay. Features: • Simple assay protocols designed for research studies (96-well plates) for HTS (384-small vol. plates) • Cell-based functional assay • Antibody-based detection • Direct detection Applications: • Gi, Gs, or Gq coupled receptor activatio…

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Biocidal ZFTM

WAK-Chemie Medical GmbH

Effectiveness: Biocidal ZFTM is effective against bacteria, spores and enveloped viruses. Non-volatile: Active microbiocidal ingredients are non-volatile.  They protect cell cultures from microbial contamination and do not invade cell cultures via air. Thus cell cultures are protected against contamination and the disinfectant itself. Application for incubators • Empty incubator • Spray Biocidal ZFTM on all surfaces and let se…

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AcroPak™ 200 Capsules with Supor® Membrane

Pall Life Sciences - Laboratory, Food, Beverage

Efficient processing of liquid volumes up to 20 litres • Supor membrane has high flow rates and throughputs, and is ideal for solutions where low protein binding is required. Not recommended for use with some ketones. • Built-in prefilter extends filter life when viscous or particulate solutions such as serum-containing media are processed. • Upstream air vent prevents vapor lock. • Manufactured without the use of adhesives to…

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AcroPak™ 500, 1000, & 1500 Capsules with Supor® Membrane

Pall Life Sciences - Laboratory, Food, Beverage

Fast, final filtration and high throughputs for liquid volumes up to 150 litres • Provides higher throughputs and faster flow rates than similarly-sized competitive devices. • Ideal for solutions requiring low protein binding. • Saves money by increasing throughput with available built-in prefilter. • 100% integrity testing assures sterile filtrate. • 0.1 µm Supor membrane version ensures sterile, mycoplasma-free cell culture…

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Hybcell - DNA or protein microarray

Anagnostics Bioanalysis

Anagnostics' hybcell is the world's first DNA or protein microarray based on the use of cylinders instead of slides. hybcell technology is... KINETIC - by means of consecutive scans, FAST - with help of rotational sample agitation, FLEXIBLE - due to fixed starting temperatures, flexible temperature profiles and computer-controlled buffer exchange and EFFICIENT - by automated processing and electronically documenting of up to 9…

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HCA Assays Kits for Cell Damage

Merck

High Content Analysis (HCA) is rapid, automated microscopy providing quantitative image acquisition and analysis. Using Millipore’s superior-quality reagents in ready-to-use kits and cell-based assays that incorporate the power of HCA, researchers around the world are able to learn more about relevant functional cell biology in many different systems, including assessment of DNA damage and apoptosis. Millipore’s HCA kits inclu…

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Hyborg - cylindrical DNA and protein analysis

Anagnostics Bioanalysis

Hyborg is a fully automated device for processing and analysing hybcells (cylindrical DNA and protein microarrays). Hyborg integrates thermocycler, hybridisation station and scanner into a single device. All processing steps - from temperature profiles or exchange of liquids to multi-color scanning - are computer-controlled and documented. Hyborg's concept of totally integrated automation guarantees maximum reproducibility o…

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Thermo Scientific BindIt 3.1 software

Thermo Fisher Scientific

Thermo Scientific BindIt™ Software has been developed for easy and versatile protocol creation for the KingFisher, KingFisher ML, KingFisher Flex and KingFisher 96 instruments. BindIt Software is highly visual and logical and has been planned for maximum user-friendliness. BindIt Software is designed to allow you to develop custom-made protocols for your own applications and run them in the KingFisher instruments. Protocols ar…

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Lightning-Link™ Alkaline Phosphatase (AP) kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Allophycocyanin (A-PC) / C-Phycocyanin (C-PC) / R-Phycocyanin (R-PC) kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ R/B/C-Phycoerythrin (R-PE/B-PE/C-PE)

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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Lightning-Link™ Peridinin-Chlorophyll-Protein complex (PerCP) kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

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