Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Thermo Scientific Mitotic Index Reagent Kit

The Mitotic Index HCS Reagent Kit provides high-content screening (HCS)-quality fluorescence reagents and a validated protocol for measurement of mitotic index, or the fraction of cells undergoing cell division within a population.

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Black Phenolic Cap with TFE Liner

WHEATON

Autoclavable caps that are designed to ensure the ultimate in product safety. The liners are made of a nontoxic white styrene-butadiene rubber and are faced with Teflon®, which offers excellent chemical resistance. Models available in range are the; • 13-425 Black Phenolic Cap with TFE Liner • 15-425 Black Phenolic Cap with TFE Liner • 22-400 Black Phenolic Cap with TFE Liner • 24-400 Black Phenolic Cap with TFE Liner For mor…

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OpenArray® Pathways Human Transcription Factors Panel Kit

BioTrove

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Transcription Factors and related genes reformatted onto an OpenArray plate. Kit includes: Open…

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OpenArray® Pathways Mouse Inflammation Panel Kit

BioTrove

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Mouse Inflammation and related genes reformatted onto an OpenArray plate. Kit includes: OpenArr…

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OpenArray® Pathways Mouse Transcription Factors Panel Kit.

BioTrove

OpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Mouse Transcription Factors and related genes reformatted onto an OpenArray plate. Kit includes…

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EPSON RS3 Robot

EPSON Robots

The EPSON RS robots are a unique new SCARA design built to reduce cycle times and maximize work envelope usage. By designing the arm so that Joint 2 can go under Joint 1, the RS3 utilizes the entire workspace underneath the arm. There is no dead space as with other SCARA models. This allows the RS3-351 model to work on pallets as large as 494mm x 494mm. A size which normally requires a 700mm SCARA arm or larger. Speed - Ne…

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Accela™ PDA Detector

Thermo Fisher Scientific

The Accela PDA is optimized for the detection of high speed chromatographic separations. The short 1 cm path length, combined with the incredibly minimized cell volume of 2 μL, renders this LightPipe flowcell as the premium choice for fast separations. The extremely low level of dispersion in the LightPipe enables the flowcell to retain the excellent peak shape and chromatographic resolution from the column. Patented LightP…

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Geniom Biochips

febit holding GmbH

febit offers a broad variety of Geniom® Biochips useable with a Geniom RT Analyzer or febit’s Analytical Services. Customers can choose from the growing portfolio of Geniom Biochips or order Custom Geniom Biochips manufactured exactly to precise specifications. Geniom Biochips are available with validated and optimized probe design for specific applications such as: • microRNA Profiling • mRNA Profiling • HybSelect, sequence c…

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Mouse Geniom Biochip

febit holding GmbH

The biochip from febit enables up-to-date profiling and enrichment of genes and SNPs of interest using Gene Expression Profiling, SNP-Detection, ncRNA analysis as well as targeted enrichment of genes for Next-Generation Sequencing (NGS).

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Cell-based ELISA

Bio-Techne

R&D Cell-Based ELISA - Dual fluorescence detection of two biomolecules simultaneously in the context of a whole cell R&D Systems Cell-Based ELISAs permit the simultaneous detection of two proteins in the same microplate well without the need for lysate preparation. Cell-Based R and D ELISA Kits come in two formats: phospho-protein kits contain antibodies to measure both the phosphorylated and the total protein, while total p…

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ATPase or GTPase Assay Kits

Innova Biosciences Ltd.

Feel the need for speed in your lead development time? The Answer – High Through Put Screening ATPase or GTPase Assays from Innova Biosciences. Is your drug discovery program for ATPase or GTPase enzymes holding you back? Still searching for an inhibitor? Then you need Innova Biosciences easy to use, GTPase or ATPase assay kits. The non radioactive colorimetric assay kits use a 96 well format, and all the necessary reagents ar…

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Vision Life Science Spectrophotometer

Hoefer Inc. Europe

The Vision diode array spectrophotometer offers 16 predefined methodologies for nucleic acid quantification (DNA, RNA, and oligonucleotides), protein assays (BCA, Biuret, Bradford, and Lowry) and for cell culture density measurements. Additionally, the Vision can accomodate up to 90 custom protocols. The visualization of the nucleic acid scan with the full graphic display is particularly useful, especially for RNA samples wh…

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BlueScreen HC: The luminescent adaptation of GreenScreen

Gentronix Ltd.

BlueScreen HC is based on the fast, accurate GreenScreen HC genotoxicity assay from Gentronix Ltd. BlueScreen HC uses the same human-derived, p53-competent TK6 cells to host a patented reporter system that exploits the proper regulation of the GADD45a gene. However, in place of GFP, BlueScreen HC utilizes a luciferase from the marine copepod Gaussia princeps to generate a luminescent output. The BlueScreen luminescent assa…

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Thermo Scientific Synaptogenesis Kit

The Synaptogenesis Kit enables simultaneous detection of neuronal population, neurite, pre-synaptic vesicle, post-synaptic puncta and synapse using a fixed end-point assay based on immunofluorescence detection in cells grown on standard high-density microplates.

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TaqMan® Protein Expression Assays

Thermo Fisher Scientific

TaqMan® Protein Expression Assays help quantitate protein expression using gold standard TaqMan® 5' nuclease chemistry with a workflow and sample quantity similar to our TaqMan® Gene Expression and MicroRNA (miRNA) Assays. As the protein expression results are obtained on the same analytical platform, these revolutionary assays enable direct correlation of mRNA and/or miRNA expression to protein expression.

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Thermo Scientific ABgene Diamond Ultra 384-well PCR Plate

Thermo Fisher Scientific

The Thermo Scientific ABgene 384-well Diamond PCR Plate is the world's most rigid 384-well PCR plate and has specifically been developed for reliable performance on high-throughput robotic handling systems. The uniform thin-wall design has been optimized for use in PCR and QPCR applications but also offers the advantage of delivering superior resistance to warping during PCR cycling, thus reducing evaporation issues associat…

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Thermo Scientific Pinpoint software

Thermo Fisher Scientific

Thermo Scientific Pinpoint software is designed to simplify the transition from early-stage biomarker discovery to larger-scale, quantitative verification of putative biomarkers and general quantitative proteomics. It takes advantage of the power of Thermo Scientific TSQ triple quadrupole mass spectrometers to generate high-confidence quantitative data. Pinpoint software is in final stages of development; but for a limited t…

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VX-200 Vortex Mixer

Labnet International

Continuously variable speed makes the Vortex Mixer VX-200 useful for a variety of applications, from gentle mixing to resuspending pellets. The unit has a circular orbit, rather than the elliptical orbit found on many other vortexers. This allows a vortexing motion to be achieved even at low Many speeds, a task that cannot be accomplished with eliptical orbit units. Many vortex mixers prevent excessive vibration with added wei…

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SureSelect DNA Capture Arrays

Agilent Technologies

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

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Cellul'erk - HTRF assay

Cisbio Bioassays

Cisbio Bioassays has developed Cellul'erk, a highly accurate HTRF assay for measuring phosphorylated ERK1/2 in 96-, 384- and 1536-well formats providing for an HTS compatible assay. Features: • Simple assay protocols designed for research studies (96-well plates) for HTS (384-small vol. plates) • Cell-based functional assay • Antibody-based detection • Direct detection Applications: • Gi, Gs, or Gq coupled receptor activatio…

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