Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Normalized cDNA libraries

Bio S&T

Our cDNA libraries feature full-length-enriched and high quality size-fractionated cDNA. cDNA library construction is usually done in slightly-modified versions of pBluescript or pcDNA3.1. Insert sizes will range from about 0.5Kb to 4Kb. Concerning QC steps, we evaluate the average insert size, empty clone rate and clone concentration/tube before shipping out. We always provide a gel picture of randomly selected clones showing…

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APAgene™ GOLD Walking Kits

Bio S&T

APAgene™ GOLD Genome Walking Kits are designed to rapidly and reliably amplify unknown genomic DNA using our patented APA technology: 1. Isolate unknown genomic sequences flanking transgenes (including T-DNAs, gene traps, transposons), sequence-tagged sites (STSs) or expressed sequence tags (ESTs). 2. Isolate localized sequences flanking known sequences from large clones and genomic DNAs. 3. Sequence insert ends of large clone…

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ASH cDNA Subtracted Library

Bio S&T

ASH is APA-based, full-length-enriched, single-stranded cDNA subtraction hybridization library. - ASH cDNA subtraction is full-length-enriched and independent of PCR suppression. - ASH cloning is directional and does not involve normalization. - ASH method provides non-exponential amplification before subtraction because double-stranded cDNA is not required. - ASH method has a better subtraction effect because 1) a high ratio…

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x-tremeGENE DNA Transfection Reagents

Improve your cell analysis and use our powerful new transfection reagents: Efficiently transfect a broad spectrum of cells, including difficult-to-transfect cell lines and tumor cell lines. Generate physiologically relevant results using low cytotoxic reagents. Avoid time-consuming optimization using fast, reliable protocols.

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SeqCap EZ Human Exome Library v3.0

Discover More, Sequence Less Built upon the NimbleGen Sequence Capture empirically optimized probe design algorithm with high efficiency uniformity of capture1, and now with expanded coverage of coding exons, SeqCap EZ Exome v3.0 offers increased performance. Capture the most comprehensive picture of the human exome with SeqCap EZ Exome Library v3.0. Based on the latest database builds and offering a 64Mb sequence capture, Seq…

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DILI Assay

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

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EPP (Endocrine Profiler Panel)

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…

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Advanced High Resolution 2-colour Fluorescence Microarray Scanner: InnoScan 910

Innopsys

Performance, Resolution, Speed. With its new detection system, the InnoScan 910 has the highest resolution and reading speed on the market. This user-friendly, two-color scanner is the ideal tool for reading current and future high-density microarrays.With outstanding sensitivity and signal-to-noise ratio derived from its highly regarded photometric properties, the InnoScan 910 is a confocal detection scanner fitted with 2 ex…

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Analysis Software for Microarray Images: Mapix

Innopsys

Simple, User-friendly, High performance.Mapix is characterised by its ease-of-use. It is a standard in the field of segmentation (automatic searching for microarray spots). Mapix has the most up to date requirements to browse data from microarray experiments quickly, with a high level of reliability and optimised productivity.Mapix can be customized, allowing users to add their own functions using its exclusive plug-in system.…

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TIGRIS® DTS™ System

GEN-PROBE Inc.

Absolute Automation Is True Walk-Away Freedom for: ■ Sample Preparation ■ Sample Processing ■ Results Analysis Only the TIGRIS® DTS™ System, with Absolute Automation, automates all phases of molecular diagnostics testing from sample preparation, amplification, and detection to reporting results. Integrating the TIGRIS DTS System with APTIMA® assay kits for nucleic acid testing (NAT) offers true freedom from hands-on processing…

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