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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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GFAP Simoa Assay Kit

Quanterix

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…

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NEUROLOGY 4-PLEX E (Aβ40, Aβ42, GFAP*, Nf-L)

Quanterix

The Simoa Human Neurology 4-Plex E (N4PE) assay simultaneously measures four biomarkers in EDTA plasma and CSF. The targets are Abeta 40 (Aβ40), Abeta 42 (Aβ42), Glial Fibrillary Acidic Protein (GFAP™), and Neurofilament light (Nf-L). Each biomarker has been demonstrated to have significance for the investigation of neurodegeneration and brain injury, and to have utility for monitoring effectiveness of drug discovery and devel…

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NEUROLOGY 2-PLEX B (Nf-L, GFAP*)

Quanterix

The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…

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