Drug discovery > Target Discovery Products & Reviews

The EarlyTox™ Cardiotoxicity Kit provides a fast, simple, and reliable fluorescence-based method for identifying cardiotoxic compounds in a biorelevant assay using stem-cell derived cardiomyocytes. Leveraging our proprietary masking technology with our novel calcium sensitive indicator, researchers can:• Eliminate cardiotoxic compounds and identify potential drug candidates• Measure 384 samples in minutes rather than h…

High-content image analysis software featuring time lapse analysis

For microplate reader validation  

Meet FDA guidelines in GMP/GLP labs with complete validation tools

High-throughput kinetic screening for lead compound identification and compound safety assessment

Perform your favorite applications including ELISA, DNA and protein quantitation, cell viability, gene expression with a user-friendly reader.  

Unique service that enables you to expand your own organoid lines to a scale large enough to suit your individual requirements. Generate more than six million assay-ready, reproducible organoid models to support your compound screening, cell model creation, or other applications. 

The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.

Celloger® Mini is an automated live cell imaging system that uses brightfield optics with fully motorized stages to provide a precise, consistent, and user-friendly solution for the users.

The first image-enabled spectral cell sorter

Siemens Healthineers offers the ELF test to help improve the assessment of NAFLD/NASH and chronic liver disease patients at risk of disease progression.

Monitor the effectiveness of TNF alpha inhibitors adalimumab, infliximab, and etanercept with one automated, cost-effective, and easily accessible assay.

CN Bio supports non-alcoholic steatohepatitis (NASH) therapeutic development via fast-track NASH Contract Research Services. NASH Services enable you to gain instant access to CN Bio’s expertise and one of the most advanced human in vitro models available. Submit lead candidates for screening and receive human translatable data for insightful preclinical candidate prioritization, clinical trial design and optimization.

Multi-chip Liver-12 consumable plates from CN Bio enable the advanced culture of 12 human 3D liver microtissues under perfusion/plate. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

Multi-chip Barrier (MPS-T12) consumable Plates from CN Bio are used to culture advanced in vitro barrier models under perfusion, such as gut-on-a-chip or lung-on-a-chip, to predict human drug responses more accurately.

CN Bio supports R&D efforts via fast-track Drug Metabolism and Safety Toxicity Testing Services that deliver human translatable insights from lead candidates in a few weeks and at lower cost than animal studies. By accessing the Company’s expertise and advanced in vitro liver-on-chip models, these Services enable researchers to step beyond standard in-house laboratory workflows for better informed pre-clinical decisions.

Multi-chip Dual-organ (MPS-TL6) consumable plates from CN Bio are used to culture interconnected 3D in vitro multi-organ-on-chip models under perfusion, such as Gut/Liver, or Lung/Liver, to generate clinically translatable data.

Multi-chip Liver-48 consumable plates from CN Bio enable the advanced culture of 48 miniaturized in vitro 3D liver microtissues under perfusion/ plate for comparative drug screens. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

It can be challenging to purify sufficient high-quality protein from mammalian cells. Boost protein recovery 30-60% with an optimized covalent protein tag, called HaloTag®. This complete kit offers strong improvements in recovery, purity, cost and protein functionality over historical FLAG® and poly-His tag purification strategies.

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to make these measurements in a single well of a plate, negating the need to run parallel assays. The first part of the assay is a nonlytic fluorescence assay (CellTiter-Fluor™ Cell Viability Assay) that measure…

Magne™ Protein G and Magne™ Protein A Beads are magnetic affinity beads with high specificity and high capacity for purification of immunoglobulins from cell culture media, ascites and serum samples.   These paramagnetic beads are composed of iron encapsulated in macroporous cellulose with low nonspecific binding. The magnetic beads use a novel attachment chemistry to immobilize recombinant Protein G or Protein A protein…

The MethylEdge™ System provides an efficient method to rapidly perform bisulfite conversion with minimal DNA fragmentation, giving you more intact, converted DNA for downstream applications.   Start with as little as 100pg of input DNA for those precious, limited samples. Use the MethylEdge™ System with other DNA Methylation Workflow reagents to perform sensitive DNA methylation analysis on many sample types. The rapi…

The BVC family of fluid aspiration systems is a compact and easy-to-use solution for cell culture work. With its portable design as well as the option of adding a second hand controller, the BVC makes working in the lab more convenient. Built-in features like a 0.2 µm hydrophobic filter and optional quick couplings increase safety while managing potentially harmful fluids. BVCs provide the flexibility to accommodate your decon…

The AttoPhos® AP Fluorescent Substrate System provides a highly sensitive fluorescent alkaline phosphatase substrate.   The system includes AttoPhos® Substrate, AttoPhos® Buffer and Calibration Solution. AttoPhos® Substrate (2′-[2-benzothiazoyl]-6′-hydroxybenzothiazole phosphate [BBTP]) is cleaved by alkaline phosphatase to produce inorganic phosphate (Pi) and the alcohol, 2′-[2-benzothiazoyl]-6´-hydroxybenzothiazole (BB…