Next Generation Sequencing Products & Reviews

Digital DNA sequencing to confidently detect low-frequency variants

An expanding portfolio of NGS panels for research into haematological and solid tumour cancers, as well as library preparation kits for the accurate detection of a wide range of genetic aberrations

The SureSeq™ Myeloid Plus NGS Complete Workflow combines the rapid Universal NGS Workflow hybridisation-based target enrichment method together with OGT’s expert bait design to detect 49 key genes implicated in myeloid disorders.

The SureSeq™ CLL + CNV Panel has been designed in collaboration with recognised cancer experts to detect 13 key genes and 5 chromosomal regions implicated in CLL progression (Table 1). The SureSeq CLL + CNV Panel alleviates the burden of running multiple assays and streamlines your CLL research to deliver a comprehensive genomic profile for each CLL sample using a single workflow

Myeloproliferative neoplasms (MPNs) are a heterogeneous group of diseases characterised by the overproduction of one or more types of blood cells. The SureSeq™ Core MPN Panel has been designed in collaboration with recognised cancer experts to detect somatic variants in 3 clinically relevant MPN associated genes; JAK2, MPL and CALR.  

The complete library preparation solution for unparalleled next generation sequencing (NGS) results. Based on scientists’ feedback, we have redesigned our workflow to ensure scientists achieve the most optimal NGS libraries, with one library preparation workflow across both our SureSeq™ and CytoSure® Constitutional NGS products.

Interpret is OGT’s powerful and easy-to-use next-generation sequencing analysis solution.

SureSelect Cancer CGP assay offers comprehensive genomic profiling for solid tumors. This pan-cancer NGS panel enables detection of somatic variants, including single nucleotide variants (SNVs), copy number variants (CNVs), insertions/deletions (indels), translocations (TLs), gene fusions, and the immuno-oncology biomarkers TMB (tumor mutational burden) and MSI (microsatellite instability).

As the framework of stellar automation, Nucleus®  Automation Infrastructure combines (A) your choice of stationary or mobile mounted collaborative robotic arms; (B) mobile cart or stationary table work surfaces to house your preferred devices; and (C) powerful Cellario™ Whole Lab Automation software. Unique MicroDock technology lets you effortlessly roll workflow devices in and out for space efficiency and manual device use.

Reagents for normalization of NGS libraries containing intact P5/P7 sequences. 

QCI Interpret Translational is a NGS variant assessment software solution that enables rapid, evidence-powered variant annotation, filtering, and triage for human exome, genome, and large cohort sequencing data. Leveraging the QIAGEN Knowledge Base, QCI Interpret Translational improves research efficiency and accuracy by automating manual curation processes, dynamically and transparently assessing variants according to soci…

CLC Combined Workbench includes all features and functions of CLC Free Workbench, CLC Protein Workbench, and CLC Gene Workbench. The program sets new standards for bioinformatics software with its overall graphical display and usability driven, user-friendly interface. In addition, it features a number of unique and innovative bioinformatics tools for supporting advanced biochemistry and molecular biology lab research. CLC Com…

CLC bio presents its new software module for Multilocus Sequence Typing (MLST). MLST is a portable and precise state-of-the-art technique for typing bacteria and yeast isolates. It is based on DNA sequence data from a number of house-keeping genes. For each gene, the experimental data is compared to a database of known alleles and a fi nal sequence type is assigned by combining information from all genes. Easy The CLC MLST Mod…

With the all new CLC RNA Workbench, CLC bio brings you complex analysis of RNA molecules in a fully integrated, user-friendly and graphically advanced bioinformatics framework. Advanced The CLC RNA Workbench gives the user easy access to a range of complex algorithms and options. RNA secondary structures can be predicted using state-of-the-art free energy minimization algorithms and parameters, thermodynamic and statistical d…

SeqCap EZ Library is a solution-based capture method that enables enrichment of the whole exome or customer regions of interest in a single test tube. Built upon an optimized design algorithm, SeqCap EZ Library sets a new standard for a simple single-step enrichment method.

The Thermo Scientific Dye Terminator Removal Kit is designed to perform the essential removal of unbound fluorescently-labelled dideoxy-ribonucleotides (ddNTPs) and excess salt from sequencing reactions prior to sequence analysis. The kit includes a 96-well plate containing pre-hydrated gel separation matrix consisting of spheres with uniformly sized pores. Sequencing reactions are passed through the separation matrix, which r…

The Thermo Scientific Separation Plate can be used for gel filtration applications (eg. dye terminator removal) when a suitable matrix is added. Features • 96 wells containing polyethylene frits, pore size of 30–45µm • 0.6ml well volume • Ready-to-use microplate format • Suitable for centrifugation

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions offer the only available method for target enrichment of RNA, allowing you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment. • The only…

Specify the genes you want to capture, and ship your genomic DNA samples to febit. febit’s experts will capture your region of interest with our HybSelect technology and send back the captured DNA to you with suggestions for the sequencing run on your SOLiD 3 system or your Illumina GAII system. Benefits • Short turn around time • Fast probe design • Available catalog Biochips for detection of cancer genes • Excellent enrichme…