Next Generation Sequencing Products & Reviews

Next-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Twist Mouse Exome Panel

Twist Bioscience

The mouse is an extremely important model system for studying genetic variation, tumor mutations, and phenotypic outcomes as well as the therapeutic effect of pharmaceutical agents. As genetic variant databases are continuously updated, the Twist Mouse Exome panel is thoughtfully designed and built from the most current databases

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Twist Human RefSeq Panel

Twist Bioscience

The superior performance of Twist Human Core Exome provides the optimal solution for sequencing of protein coding genes. The Twist Human Core Exome however focuses only on the most accurate curated subset—CCDS database. Twist now offers the Twist Human RefSeq Panel, which is designed to expand the content of the Twist Human Core Exome. When combining the two panels, greater than 99% of protein coding genes are covered.

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Twist Library Preparation MF Kit (Mechanical Fragmentation)

Twist Bioscience

Twist Library Preparation Kit (Mechanical Fragmentation) is designed for use with gDNA that has already been sheared mechanically. It combines the enzymes and reagents for end repair, dA-tailing, and adapter ligation into a single reaction: Accommodates a wide range of DNA input types, enables high-quality sequencing of low-quality samples and minimizes start / stop site artifacts

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Twist Library Preparation EF Kit (Enzymatic Fragmentation)

Twist Bioscience

Twist Library Preparation EF Kit (Enzymatic Fragmentation) incorporates the reagents and enzymes needed for DNA fragmentation with those for end repair, dA-tailing, and adapter ligation into a single reaction:  Ideal for automated, high-throughput library preparation, produces tunable, reproducible fragment sizes and minimizes sequence bias, maximizes coverage depth.

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