UHPLC and HPLC Products & Reviews

High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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SeQuant® ZIC®-HILIC HPLC Columns

Merck KGaA, Darmstadt, Germany

ZIC®-HILIC HPLC columns for the separation of all classes of polar and hydrophilic compounds. What is HILIC? HILIC or Hydrophilic Interaction Liquid Chromatography is a straightforward chromatographic technique for separation of many types of polar and hydrophilic compounds. To put it simple one can say that HILIC is a normal-phase (NPLC) type of separation but uses reversed-phase (RPLC) type eluents. In HILIC one has: A c…

3.9/5.0
|7 Reviews
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Purospher® STAR HPLC and UHPLC columns

Merck KGaA, Darmstadt, Germany

The base silica of Purospher® STAR columns is 99.999 % pure. Furthermore, meticulous care is given to quality control over all aspects of silica structure and chemistry. The excellent converge of the surface and the purity of the material ensures excellent peak symmetry for acidic, basic and even for chelating compounds. Accurate results with excellent peak shape for all types of analytes Outstanding resolution due…

4.3/5.0
|3 Reviews
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LiChrosolv® Hypergrade Solvents for LC-MS

Merck KGaA, Darmstadt, Germany

High purity solvents for LC-MS and trace analysis with UV and fluorescence detection: 0.2 µm stainless steel filtered – perfect for use in UPLC and UHPLC. Very high UV-transmittance. Excellent baseline stability in gradient elution. Very low total ionic current (TIC) in LC-MS. Low level of ionic background and ion suppression. High ionization efficiency in all ionization methods (electrospray ionization/atmospher…

4.0/5.0
|1 Review
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InertSustain C18

GL Sciences, Inc.

Silica-based columns are stable and efficient but unsuitable for alkaline analyses due to the silica matrix's weakness under high pH. InertSustain C18, with its novel surface-modified silica, overcomes this limitation. It retains Inertsil's benefits—low back pressure, superior inertness, high efficiency, consistent performance, and wide solvent compatibility—while enabling analyses over a broad pH range.

4.2/5.0
|3 Reviews
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Chromaster Analytical HPLC System

Hitachi High Technologies America, Inc.

The Chromaster Analytical HPLC System from Hitachi has established new limits in Performance, Ease-of-Use, and Robustness. Innovative low-pressure gradient mode, “High Frequent Mode,” and Hitachi’s proprietary real-time feedback control system greatly suppress liquid pulsation resulting in unparalleled retention time and gradient reproducibility. The Hitachi Chromaster is also available with 60 MPa maximum pressure.

3.9/5.0
|3 Reviews
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Hitachi LaChrom Elite® HPLC System

Hitachi High Technologies America, Inc.

Designed to meet the challenges of today's laboratory environment, fast results and demanding workload, LaChrom Elite® couples automated tasks with innovative design. Control by Empower™ 2 software facilitates regulatory compliance Features Innovation • System synchronization, Pump-Autosampler Synchronization (PASS) This unique feature means that each injection occurs at exactly the same point in every pump cycle ensuring the…

3.9/5.0
|12 Reviews
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Hitachi LaChromUltra® U-HPLC System

Hitachi High Technologies America, Inc.

Hitachi's Ultra High-Speed Liquid Chromatograph, LaChromUltra,delivers ultra-fast analysis, higher resolution, increased sensitivity and the flexibility to run both conventional and ultra-high resolution LC analyses on a single system. LaChromUltra is the practical next generation LC solution that meets your laboratory's changing needs AND fits your budget Features • 60 MPa (8700 psi) pressure max and 2.0 µm particle size colu…

4.3/5.0
|1 Review
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Ascentis® Express U/HPLC Columns

Merck

The Fused-Core ® particle technology behind Ascentis ® Express columns delivers maximum speed and efficiency on both HPLC and UHPLC systems. The novel superficially porous silica particles (SPP) are available in three different particle sizes and two different pore sizes for optimal suitability from micro over UHPLC and HPLC to semi-preparative use.

4.3/5.0
|1 Review
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