ADME-Toxicology Products & Reviews

A novel cellular probe that can enter both INTACT and compromised cells.

A novel, far-red fluorescing dye that reveals hypoxic experience of individual cells.

Get the full picture of cell behavior over time. 

BC001 - 2-channel biochip with narrow cavities for organ-on-chip models by Dynamic42

BC002 - 2-channel biochip with wide cavities for organ-on-chip models by Dynamic42

BC003 - 3-channel biochip with cavities for spheroid/ organoid-on-chip models by Dynamic42

BC005 - 2-channel biochip with thin channels for organ-on-chip models with limited cell material by Dynamic42

Service for toxicology screening,  lead identification/ optimization and in vitro model development using organ-on-chip technology by Dynamic42

Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.     

Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.

The only kit you’ll need to build your own organ-on-chip

The open organ-on-chip platform

Afla-V AQUA Strip Tests utilize the proven sensitivity and selectivity of VICAM's monoclonal antibodies to accurately detect and measure total aflatoxins (B1, B2, G1 & G2) at levels as low as 2.5 ppb and as high as 50 ppb. Afla-V AQUA eliminates the need for hazardous solvents using a water-based, dilution-free extraction procedure that develops in just 5 minutes. Results are displayed on the digital screen and may also be pr…

for Latex Agglutination and Latex Turbidimetry Immunoassay

Differentiates live cells from dead cells via fluorescent labeling

The EarlyTox™ Cardiotoxicity Kit provides a fast, simple, and reliable fluorescence-based method for identifying cardiotoxic compounds in a biorelevant assay using stem-cell derived cardiomyocytes. Leveraging our proprietary masking technology with our novel calcium sensitive indicator, researchers can:• Eliminate cardiotoxic compounds and identify potential drug candidates• Measure 384 samples in minutes rather than h…

CN Bio supports non-alcoholic steatohepatitis (NASH) therapeutic development via fast-track NASH Contract Research Services. NASH Services enable you to gain instant access to CN Bio’s expertise and one of the most advanced human in vitro models available. Submit lead candidates for screening and receive human translatable data for insightful preclinical candidate prioritization, clinical trial design and optimization.

CN Bio supports R&D efforts via fast-track Drug Metabolism and Safety Toxicity Testing Services that deliver human translatable insights from lead candidates in a few weeks and at lower cost than animal studies. By accessing the Company’s expertise and advanced in vitro liver-on-chip models, these Services enable researchers to step beyond standard in-house laboratory workflows for better informed pre-clinical decisions.

The Glucose-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glucose in biological samples.

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.