ADME-Toxicology Products & Reviews

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ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Trypan Blue

Bio-Rad

10 x 1.5 ml, sufficient for 1,500 counts (10 µl/count), 0.4% in 0.81% sodium chloride and 0.06% potassium phosphate dibasic solution, sterile filtered, for use with TC10™ or TC20™ automated cell counter.

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CFDA-SE

Bio-Rad

Use the CFDA-SE (5[6]Carboxyfluorescein diacetate, succinimidyl ester) cell-permeable dye to monitor cell population health.

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ReadiDrop™ Propidium Iodide

Bio-Rad

Commonly used in flow cytometry experiments for excluding dead cells, the propidium iodide solution enters a compromised cell and binds to double-stranded DNA/RNA by intercalating between base pairs.

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ReadiDrop™ 7-AAD

Bio-Rad

The ReadiDrop™ 7-aminoactinomycin D (7-AAD) cell viability assay is designed as a ready-to-use 7-AAD solution, which binds double-stranded DNA with a high-affinity intercalation between GC base pairs.

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ADAM-SCC2 Automated Somatic Cell Counter

NanoEntek

ADAM-SCC2, a fast, easy and accurate automated somatic cell counter, is composed of fluorescence optic and image analysis software. It can be useful equipment for dairies, smaller labs and veterinary establishments working with somatic cell analysis. It is helpful to the implementation of milk quality control.

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NucSpot Nuclear Stains

Biotium

Cell membrane-impermeant, nuclear-specific counterstains. Suitable for fixed cells or staining dead cells in live cultures. Available in a variety of colors from green to near-infrared (near-IR).

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StarDrop 5 - Drug Discovery Software

Optibrium

StarDrop is a suite of software that helps you to deliver optimally balanced, effective drugs - fast StarDrop works by evaluating complex data, which is often uncertain because of experimental variability or predictive error. In scoring this data, it brings confidence and intuitive simplicity to decision-making: guiding and validating the direction you take and which compounds you prioritise. Its instantly interactive tools t…

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Apo-Direct TUNEL Assay Kit

Merck

The CHEMICON APO-DIRECT™ Kit is a single-step staining method for labeling DNA breaks to detect apoptotic cells by flow cytometry (Li et al. 1995). The kit contains all the reagents required for measuring apoptosis in cells including positive and negative control cells; washing, reaction, and rinsing buffers; and propidium iodide/RNase A solution for counter staining the total DNA.

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MitoLight® Mitochondrial Apoptosis Detection Kit

Merck

The MitoLight™ Apoptosis Detection Kit utilizes a lipophilic cation, termed as MitoLight™, as a mitochondrial activity marker. MitoLight™ is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. The monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential. MitoLight™ partitions differently i…

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