ADME-toxicology (ADME-Tox) studies are used in pharmacology and pharmacokinetics to assess the activity/toxicity of drugs <i>in vivo</i> or <i>in vitro</i>. Find bioassays for absorption, distribution, metabolism, and excretion of drug molecules including cytotoxicity, transporter/permeability, metabolism and activity assays as well as hepatocytes and cell lines for ADME. Find the best ADME-toxicology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
CFSE Cell Division Tracker Kit is composed of 5 vials, 100 µg per vial of CFSE (formally known as 5-(and 6)-Carboxyfluorescein diacetate succinimidyl ester of CFDA SE), and 500 µl of anhydrous DMSO. CFSE is able to passively diffuse into cells. Inside the cell, its acetate groups are cleaved by intracellular esterases, and the molecules are converted to fluorescent esters. CFSE is retained within the cell and covalently couple…
HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%.
Agilent Seahorse XF HS Mini Analyzers measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells in an eight-well miniplate format. The quick and easy setup makes the Seahorse XF HS Mini Analyzer ideal for performing routine energy metabolism measurements of ex-vivo and other quantity-limited samples. Features Analyzer is compatible with XFp miniplates and XFp PDL miniplates for rout…
Get high quality cell viability results and instant time savings
V-PLEX validated immunoassays deliver reproducible, reliable results to support the most demanding long-term studies. Offering exceptional dynamic range, high sensitivity, and lot-to-lot consistency, V-PLEX assays are available as individual analyte kits and in preconfigured and custom multiplex panels.
Measure mitochondrial respiration, glycolysis, and ATP production rates in live cells in a 96-well forma t, providing a system-level view of cellular energy metabolism and mitochondrial health. It combines enhanced sensitivity and data consistency with intuitive software and advanced data analytics, enabling users to streamline assay workflow from start to finish and generate and interpret metabolic data easily.
The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. With the latest add-on fluorescence module, cell biologists benefit from minimizing light exposure and reducing photocytotoxicity when automatically obtaining accurate live-cell morphology, migration, proliferation data, and multi-well time-lapse videos down to a single-cell level in real-time.
Application The Cell Proliferation Reagent WST-1 is designed to be used for the nonradioactive, spectrophotometric quantification of cell proliferation and viability in cell populations using the 96-well-plate format. It can be used for: Measurement of cell proliferation in response to growth factors, cytokines, mitogens, and nutrients Analysis of cytotoxic and cytostatic compounds, such as anti-cancer drugs and other ph…
