Combinatorial Chemistry Products & Reviews

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Combinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.

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Supercritical Reactors/ Reaction Systems

Waters

Thar's SuperReactor/Extractor systems are built to enable the user to rapidly react multiple compounds with supercritical CO2, video record it occuring, then extract materials of interest. The user can operate in a static, pressure control mode or a dynamic flow control mode. No other company in the world produces off-the-shelf, automated SFR/SFE kits for use in pharmaceutical, chemical and food research laboratories. Superc…

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High Pressure Pumps

Waters

Thar designs and manufactures high pressure pumps ideally for high pressure and high temperature applications, such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, solvent extractions. The pumps can be controlled using a hand-held display (included) or PC via the built-in RS232C interface. The high pressure pump can be used in conjunction with additional…

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PoraPak Rxn

Waters

Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…

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Biotage® PhyPrep System

Biotage

Biotage® PhyPrep automates the purification of plasmid DNA from cell pellets at the Maxi, Mega and Giga scales. The result is highly pure, endotoxin-free plasmid DNA – the optimal starting point for downstream applications, such as transient transfection. Biotage® PhyPrep comes with everything needed to generate highly pure plasmids, from a simple sample preparation step to a fully automated purification procedure, freeing up…

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SynPhase Lanterns

Mimotopes

SynPhase Lanterns are the latest generation of grafted products optimized for small organic molecule and peptide synthesis.The SynPhase Lantern is cylindrical in appearance and is available in three different sizes, L-series, D-series and A-series with physical dimensions as shown in the table below. These properties make the SynPhase Lantern compatible with a wide range of reaction vessels and synthesizers.

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ASINEX Unique Building Blocks

Asinex Ltd

Do you need interesting and unique building blocks for you small molecule combinatorial program? If you look at our 3500 In-House designed and externally acquired building blocks (from contract chemists) we are sure you will agree that this is a unique collection. These building blocks cannot be found in the major catalogues.

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StarDrop 5 - Drug Discovery Software

Optibrium

StarDrop is a suite of software that helps you to deliver optimally balanced, effective drugs - fast StarDrop works by evaluating complex data, which is often uncertain because of experimental variability or predictive error. In scoring this data, it brings confidence and intuitive simplicity to decision-making: guiding and validating the direction you take and which compounds you prioritise. Its instantly interactive tools t…

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Gigapack III Packaging Extracts

Agilent Technologies

The single-tube format of Gigapack III packaging extract simplifies the packaging procedure and increases the efficiency and representation of libraries constructed from highly methylated DNA. The ability of Gigapack III packaging extracts to preserve methylated DNA makes it ideal for use in epigenetic studies where DNA methylation may be associated with heritable changes in gene expression or cellular phenotype.

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Markers & Restriction Enzymes

Agilent Technologies

Restriction Enzymes Dpn I is an ideal enzyme for cloning and Southern blot analysis High purity enzyme preparation Includes 10X universal reaction buffer Glogos II Autorad Markers Luminescent peel-off stickers used for accurately marking and aligning autoradiographs. Easily affixed to plastic wrap or paper, these convenient markers emit low-level luminescence rather than radioactivity, making the Glogos II m…

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FIAstar™ 5000 Systems

Foss Tecator AB

The FIAstar™ 5000 System is used for the automatic wet chemical analysis of nutrients and other parameters in water, soil and wine, as well as in meat or other food products. Single or multiple parameters can be analysed sequentially using just one Analyser module and Plug & Analyse Method Cassettes. The modular system can be expanded for the simultaneous determination of up to three parameters.The Plug & Analyse concept ensur…

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Catalysts

Alfa Aesar

Alfa Aesar offers a full range of precious metal salts and solutions manufactured to stringent specifications. Homogeneous catalysis provides an excellent choice where highly specific reactions are desired including chiral transformations. Our homogeneous catalysts can be used in a wide range of chemical transformations. Supported (heterogeneous) precious metal catalysts are used in a variety of reactions including hydrogena…

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