Combinatorial Chemistry Products & Reviews

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Combinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.

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Supercritical Reactors/ Reaction Systems

Waters

Thar's SuperReactor/Extractor systems are built to enable the user to rapidly react multiple compounds with supercritical CO2, video record it occuring, then extract materials of interest. The user can operate in a static, pressure control mode or a dynamic flow control mode. No other company in the world produces off-the-shelf, automated SFR/SFE kits for use in pharmaceutical, chemical and food research laboratories. Superc…

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High Pressure Pumps

Waters

Thar designs and manufactures high pressure pumps ideally for high pressure and high temperature applications, such as supercritical fluid chromatography (SFC), HPLC, supercritical fluid extraction (SFE), particle formation, reactions, solvent extractions. The pumps can be controlled using a hand-held display (included) or PC via the built-in RS232C interface. The high pressure pump can be used in conjunction with additional…

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PoraPak Rxn

Waters

Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…

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Biotage® PeptiPEC-96 High Throughput Kit

Biotage

Biotage® PeptiPEC-96 High Throughput Kits streamline peptide purification with the automated PurePep® Easy Clean (PEC™) catch-and-release strategy. Purify 96 peptides simultaneously while removing impurities efficiently for cleaner, higher-quality peptide libraries.

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Biotage® PeptiRen-96 Well-plate

Biotage

Biotage® PeptiRen-96 well plates streamline peptide library workflows by enabling simultaneous post-synthesis clean-up of 96 crude peptides. Featuring reversed-phase media optimized for peptide SPE, they provide an efficient, automatable solution for rapid enrichment and preliminary screening.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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Nucleic Acids Reference Standards

Cambridge Isotope Laboratories

Nucleic acids are necessary biomolecules of living systems being fundamentally important to a multitude of cellular processes. Its basic building blocks are nucleobases (e.g., adenine, cytosine, xanthine), nucleosides (e.g., adenosine, guanosine, inosine), and nucleotides (e.g., ATP, CDP, dGTP). The qualification/quantification of these compounds, and their synthetic analogs (e.g., 5-fluorouracil), in biosamples, is performed…

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SynPhase Lanterns

Mimotopes

SynPhase Lanterns are the latest generation of grafted products optimized for small organic molecule and peptide synthesis.The SynPhase Lantern is cylindrical in appearance and is available in three different sizes, L-series, D-series and A-series with physical dimensions as shown in the table below. These properties make the SynPhase Lantern compatible with a wide range of reaction vessels and synthesizers.

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ASINEX Unique Building Blocks

Asinex Ltd

Do you need interesting and unique building blocks for you small molecule combinatorial program? If you look at our 3500 In-House designed and externally acquired building blocks (from contract chemists) we are sure you will agree that this is a unique collection. These building blocks cannot be found in the major catalogues.

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