HTS Libraries
EMD Millipore's cloned human S1P5-expressing cell line is made in the Chem-5 host, which supports high levels of recombinant S1P5 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between S1P5 and its ligands.
EMD Millipore's S1P5 membrane preparations are crude membrane preparations made from our proprietary stable recombinant cell lines to ensure high-level of GPCR surface expression; thus, they are ideal HTS tools for screening of S1P5 interactions with its ligands. The membrane preparations exhibit EC50s of 2.4 nM for S1P in a GTPγS binding assay.
EMD Millipore’s cloned human GPR92 -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant GPR92 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at GPR92.
EMD Millipore’s cloned human GPR91 -expressing cell line is made in the Chem-1 host, which supports high levels of recombinant GPR91 expression on the cell surface and contains high levels of the promiscuous G protein to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for agonists and antagonists at GPR91.
Chemicon's Wild-Type Chem-1 cell line is a control for Chemicon's GPCR-expressing Chem-1 calcium-optimized cell lines. The Chem-1 cell line is adherent to tissue culture-treated surfaces and contains high levels of the promiscuous G protein Galpha15 to couple many classes of GPCRs to the calcium signaling pathway.
The AdEasy system saves you a month of work over traditional methods by producing the recombinant adenoviral plasmid by homologous recombination in E. coli. The AdEasy XL system includes BJ5183 cells pre-transformed with the pAdEasy-1 plasmid, this feature dramatically decreases background caused by the non-recombinant shuttle plasmid.
The following pages contain an extensive range of commonly used peptides available from stock. If you can not see what you require in our inventory why not let us quote you for the synthesis. Just email us the sequence and we will get back to you within 48 hours with a competitive quote. Quality is our number one priority to ensure our peptides meet or exceed your specifications. All Peptides are HPLC purified and supplied wit…
New from Agtcbioproducts: Bio Integration Technology, Inc. Is dedicated to developing, manufacturing and marketing new chiral molecules for for Drug Discovery. There products include fluorinated amino acids the enhance protein stability, protein-protein as well as ligand-receptor interactions and the physical properties of protein-based or peptide-based biologically active molecules. They can also supply a range of synthetic p…
Recombinant Rubella (strain F-Therien) virus-like particles consisting of spike glycoprotein E1, spike glycoprotein E2 and Capsid protein, produced in mammalian HEK293 cells.
Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S1) is a recombinant antigen which contains the Spike protein amino acids 1-674. Spike S1 protein is manufactured in HEK293 mammalian cells, ensuring the most authentic post-translational modifications.
Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike S2 protein, amino acids 685-1211. Spike S2 is manufactured in mammalian HEK293 cells to ensure the most authentic post-translational modifications.
SARS-CoV-2 Nucleoprotein is a recombinant antigen manufactured in E. coli cells to high purity for use in vaccine research and immunoassay development. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike protein amino acids 685-1211 of subunit 2. Spike S2 protein is manufactured to high yield and purity using the Native Antigens baculovirus-insect cell platform. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
SARS-CoV-2 Spike-E-M Mosaic protein is a recombinant antigen manufactured in E. coli with greater than 95% purity, and containing the Spike (S), Envelope (E) and Membrane (M) immunodominant regions. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
Human Coronavirus 229E Nucleoprotein is a recombinant protein containing 359 amino acids derived from the nucleocapsid sequence, with a C-terminal 6xHis tag. It is manufactured in E. coli with greater than 95% purity.
DNA variant libraries for expression of antibodies, antigens and other proteins.
India Variant B.1.617 Spike Protein, as well as spike mutant proteins from the UK, South African, and Brazilian Variants. Available now!
Ectodomain, stabilized prefusion conformation, resistant to furin cleavage
Tn5 insect cell expressed, high ACE-2 binding
HEK293 expressed, high ACE-2 binding
Sf21 insect cell expressed, over 95% purity
SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that are commonly comprised of four structural proteins. One of the proteins, SARS-CoV-2 Spike Protein (S Protein), is a glycoprotein that mediates membrane fusion and viral entry, and as such is a crucial COVID-19 target. R&D Systems SARS-CoV-2 Spike range of bioactive proteins are valida…
CHO expressed. GCN4-IZ trimerization domain. Prefusion Conformation. High ACE-2 binding
